Results 51 to 60 of about 18,250 (170)
Development of a three‐step synthesis and replacement of the cycloheptyl moiety in cycloheptathiophene‐3‐carboxamide derivatives revealed how thiophene C‐5 substitutions modulate PA–PB1 inhibition, antiviral potency, and water solubility. The phenyl analog 9 delivered sub‐µM potency across multiple IV strains, while the methyl analog 5 achieved the ...
Tommaso Felicetti +8 more
wiley +1 more source
MVP Inhibits Influenza A Virus‐Induced Ferroptosis by Targeting IRF1 and Increasing FSP1 Activity
During IAV infection, MVP inhibits IRF1 polyubiquitination, thereby relieving IRF1‐mediated transcriptional inhibition of FSP1. Consequently, this leads to an upregulation of FSP1 expression, thereby reinforcing the inhibition of ferroptosis. In addition, the MVP can promote myristoylation and ubiquitination of FSP1, enabling its membrane localization ...
Yingbo Chen +12 more
wiley +1 more source
Influenza D Virus Infection in Feral Swine Populations, United States
Influenza D virus (IDV) has been identified in domestic cattle, swine, camelid, and small ruminant populations across North America, Europe, Asia, South America, and Africa. Our study investigated seroprevalence and transmissibility of IDV in feral swine.
Lucas Ferguson +13 more
doaj +1 more source
Natural Extracts as Candidate Influenza Vaccine Adjuvants. Seasonal influenza vaccines face limitations due to viral mutations and low efficacy in vulnerable populations. Traditional adjuvants often have safety or immune‐activation constraints, leading to increased interest in natural extracts from plants, marine organisms, and fungi.
Thi Len Ho, Eun‐Ju Ko
wiley +1 more source
Walsh & Hoyt: Orthomyxoviridae
The viruses in the family Orthomyxoviridae were once grouped together with several other viruses, including the mumps and measles viruses, in a single family, Myxoviridae.
Paul W. Brazis, MD, Neil R. Miller, MD
core
Development of an influenza virus vaccine using the baculovirus-insect cell expression system : implications for pandemic preparedness [PDF]
Key word Influenza, rHA, vaccine, baculovirus, insect cells, production, pandemic preparedness Influenza (or flu) is a highly contagious, acute viral respiratory disease that occurs seasonally in most parts of the world and is caused by influenza ...
Cox, M.M.J.
core
A novel broad-spectrum treatment for respiratory virus infections : influenza-based defective interfering virus provides protection against pneumovirus infection in vivo [PDF]
Respiratory viruses represent a major clinical burden. Few vaccines and antivirals are available, and the rapid appearance of resistant viruses is a cause for concern.
Edworthy, Nicole Lynn +11 more
core +1 more source
This study presents a portable, smartphone‐linked multi‐channel magnetoelastic sensor for the simultaneous detection of three airborne livestock viruses (H1N1, CSFV, FMDV). The multi‐channel sensor demonstrates linear, virus‐specific frequency shifts over its detection range, and the accuracy of this device is comparable with that of vector network ...
Yunxuan Zhang +9 more
wiley +1 more source
Unusual Influenza A Viruses in Bats
Influenza A viruses infect a remarkably diverse number of hosts. Two completely new influenza A virus subtypes were recently discovered in bats, dramatically expanding the host range of the virus.
Andrew Mehle
doaj +1 more source
ABSTRACT Background Epidemiological surveillance of influenza D virus (IDV) has gained increased priority following recent serological findings indicating its potential zoonosis in humans. In this context, it is crucial to develop strong, reproducible, reliable and scalable immunological assays that can be quickly implemented in the surveillance of new
Maria Giovanna Marotta +10 more
wiley +1 more source

