Results 171 to 180 of about 2,205,919 (212)

ANK1 and EPB41 Variants and The Risk of Glucocorticoid‐Induced Osteonecrosis

Arthritis &Rheumatology, EarlyView.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, EarlyView.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

MDL‐800‐induced SIRT6 activation decreases age‐associated osteoarthritis in mice

Arthritis &Rheumatology, Accepted Article.
Objective SIRT6 is a nuclear‐localized histone deacetylase that regulates multiple pathways associated with aging. This study aimed to determine whether systemic administration of a small molecule activator of SIRT6, MDL‐800, decreases the severity of age‐associated osteoarthritis (OA) in mice.
Matheus Moreira Perez, Pranay Ramteke, Bahiyah Watson, Owen Haslam, Eirene Choi, Susan Chubinskaya, Mandy J. Peffers, William R. Davis, Jacqueline Shine, Brian O. Diekman, Richard F. Loeser, Theresa A. Freeman, Makarand V. Risbud, John A. Collins   +13 more
wiley   +1 more source

Departing from standard practices: Strategic application of value engineering in the anatomy laboratory to enhance formaldehyde extraction using high‐impact, low‐cost, and low‐maintenance solutions

Anatomical Sciences Education, Volume 18, Issue 3, Page 241-253, March 2025.
Abstract This study describes the process of developing a high‐impact, low‐cost, and low‐maintenance air ventilation system for anatomy facilities. It employed the strategic application of Value Engineering (VE), assuring that the air ventilation system meets contemporary threshold limit values (TLVs) for formaldehyde in the working zone of dissection ...
Jürgen Russ, Niels Hammer
wiley   +1 more source

From classroom to clinic: Evaluating the educational utility of two Thiel embalming methods

Anatomical Sciences Education, EarlyView.
Abstract Over three decades since its introduction, the Thiel embalming method remains a widely used and praised technique in anatomical education and clinical training. This study compared for the first time the Thiel original protocol (TO) and a Modified version (TM) across user groups—undergraduate medical students, student demonstrators in anatomy,
Veronica Antipova, Martin Siwetz, Simone Manhal, Niels Hammer   +3 more
wiley   +1 more source

Accurate Measurement in All‐inside Posterior Cruciate Ligament Reconstruction: A Technical Note

Arthroscopy Techniques, EarlyView.
Abstract With the increasing rate of posterior cruciate ligament reconstruction (PCLr) and growing adoption of the all‐inside PCLr, the existing literature lacks an optimal surgical protocol for this technique. It is well recognized that variations in knee size and intraoperative positioning pose challenges in determining the key parameter—the length ...
Daoliang Xu, Wei Yu, Zelin Jiang, Jianxia Wen, Xiaoyun Pan   +4 more
wiley   +1 more source

Suture Augmented Ulnar Collateral Ligament Reconstruction: A Detailed Technique

Arthroscopy Techniques, EarlyView.
Abstract Suture augmentation is frequently being used for medial ulnar collateral ligament (UCL) repair and many surgeons now augment UCL reconstructions with a high strength suture. This article and video describe the technique of suture augmented UCL reconstruction.
Carson H. Gardner, Seena Sebt, Kenneth H. Akizuki   +2 more
wiley   +1 more source

Modified Transtibial Pullout Repair for Medial Meniscus Posterior Root Tear Using a Barbed Suture: A Technical Note

Arthroscopy Techniques, EarlyView.
Abstract This technical note describes a modified transtibial pullout repair for medial meniscus posterior root tear incorporating a barbed suture to improve fixation strength and load distribution. The technique combines 2 simple sutures placed near the torn root with a circumferential barbed suture passed through the posteromedial meniscocapsular ...
Nam Jun Baek, Wonchul Choi, Jae‐Young Park, Jae Youn Yoon, Jonghyun Park, Jun‐Bae Kim   +5 more
wiley   +1 more source

Arthroscopic Dynamic Anterior Stabilization and Augmentation of Bony Bankart Lesions With Transfer of the Long Head of the Biceps

Arthroscopy Techniques, EarlyView.
Abstract Bony Bankart fractures treated arthroscopically with conventional suture anchor fixation are often complicated by fragment displacement and nonunion because of inadequate reduction. This technical report introduces a novel technique using the long head of the biceps (LHB) tendon transfer for elevating bony fragment and augmenting suture anchor
Wei Su, Xiaokang Wei, Jinzhong Zhao, Guoming Xie   +3 more
wiley   +1 more source

The “McFL‐LARS” Hybrid Technique: Fascia Lata Autograft and Synthetic Reinforcement for Combined Revision Anterior Cruciate Ligament Reconstruction and Lateral Extra‐articular Tenodesis

Arthroscopy Techniques, EarlyView.
Abstract Anterior cruciate ligament reconstruction using fascia lata autograft is a validated technique but remains limited by graft diameter or by the need to harvest a hamstring tendon. This report describes a novel hybrid approach, the “McFL‐LARS” hybrid technique, combining fascia lata autograft with a ligament advanced reinforcement system ...
Bernard de Geofroy, Adeniran Ogou, Olivier Barbier, Matthieu Peras, Paul Teixeira, Louis‐Marie Pessey, Camille Choufani   +6 more
wiley   +1 more source