Results 181 to 190 of about 2,205,919 (212)

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Real‐time biosensing of Parkinson's disease biomarkers via NIR‐activated upconversion nanoparticles

open access: yesBMEMat, EarlyView.
Schematic illustration of the luminescence resonance energy transfer‐driven core‐shell‐shell UCNPs (cssUCNPs@Fluo4) nanoprobe for simultaneous monitoring of Ca²⁺‐temperature dynamics in Parkinson's disease models. Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with incompletely understood pathophysiology, necessitating ...
Jialin Liu   +9 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

open access: yesBMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma   +8 more
wiley   +1 more source

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

open access: yesBMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu   +9 more
wiley   +1 more source

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

open access: yesBMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu   +8 more
wiley   +1 more source

Multifunctional polycaprolactone‐based composite fibers with icariin and glutathione for effective repair of critical‐sized bone defects

open access: yesBMEMat, EarlyView.
A multifunctional PCL‐based scaffold co‐delivering Icariin and Glutathione synergistically enhances osteogenesis, angiogenesis, and oxidative stress resistance, achieving near‐complete repair of critical‐sized bone defects in vivo. This cell‐free platform represents a promising strategy for accelerated bone regeneration.
Abdurohman Mengesha Yessuf   +11 more
wiley   +1 more source

Innovation in the Face of Necessity: A Mixed‐Method Study of Student's Experience From an Anatomy Education Program Focused on a Near‐Peer Tutoring Module

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Following institutional changes that reduced access to cadaveric dissection, Paris‐Saclay University developed a two‐year elective anatomy pathway serving as a longitudinal progression toward near‐peer tutoring (NPT). Designed as a complement to the core curriculum, the program preserves engagement with human dissection while promoting ...
Maud Creze   +5 more
wiley   +1 more source

Vascularization of the Ulnar Nerve: Anatomical Feasibility as a Vascularized Nerve Graft for Contralateral C7 Transfer

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Recent advances in brachial plexus reconstruction have highlighted the potential advantages of vascularized nerve grafts for functional recovery in high‐priority nerve injuries. This anatomical study evaluated the extrinsic vascular supply of the ulnar nerve based on the superior ulnar collateral artery (SUCA) in the arm, aiming to assess its ...
M. Rosa Morro‐Martí   +7 more
wiley   +1 more source

A Novel Anatomical Description of the Normal Terminal Fibular Artery and the Terminal Fibular Window: Radiological Findings and Surgical Implications

open access: yesClinical Anatomy, EarlyView.
ABSTRACT A novel anatomical description and radiological finding, related to the anatomical course of the terminal fibular artery (FibA) was recently reported. In the article, the authors found the terminal FibA to change its course, from being posterior and medial to the fibula to surface anteriorly and laterally before residing below the tibiofibular
Sebastian Kirdar‐Smith   +5 more
wiley   +1 more source

Variant Anatomy Literacy as a Patient‐Safety Competency in Surgical Training: A Title‐Informed Conceptual Review and Competency Framework

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Surgical safety depends on recognition of patient‐specific anatomy when encountered structures depart from population norms. Knowledge of anatomical variations is often treated as supplemental rather than as a safety‐relevant necessity.
Juan A. Sanchis‐Gimeno   +4 more
wiley   +1 more source

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