Results 211 to 220 of about 39,132 (298)

From Pharmaceutical to Biophysical Therapies: New Horizons in Inflammatory Bowel Disease Management

JCC Plus, Volume 1, Issue 2, March 2026.
Important limitations exist in the current pharmacological landscape of Inflammatory Bowel Disease (IBD), such as variable response rates and treatment‐limiting adverse effects. In this review, we perform a critical assessment of the current literature on novel multimodal biophysical approaches showing alternative mechanisms of action to, and potential
Benedetta Ricchi, Alejandra A. Carriles, Samuel Elias Pineda Chavez, Stefanos Bonovas, Arianna Dal Buono, Cristina Bezzio, Alessandro Armuzzi, Stefania Vetrano   +7 more
wiley   +1 more source

Extracellular Vesicles From Mesenchymal Stromal Cells Drive Muscle and Neuronal Regeneration Through TNFα Modulation

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
Workflow of the work. (1) Human muscle biopsies were collected, and the human muscle precursor cells (hMPC) were isolated, followed by co‐culture with human monocytes (THP‐1). In parallel, human muscles were decellularised to obtain an extracellular matrix (ECM) free of cells. ECM were recellularised by injecting hMPC and THP1 into the matrix.
Agner Henrique Dorigo Hochuli, Stefania D'Agostino, Lucia Rossi, Beatrice Auletta, Leonardo Nogara, Giovanni Tafuro, Giuseppe Germano, Alice Zaramella, Paola Bisaccia, Francesca Cecchinato, Carlo Biz, Gabrielis Kundrotas, Pietro Ruggieri, Alessandra Semenzato, Maurizio Muraca, Filippo Romanato, Piergiorgio Gamba, Marcin Jurga, Bert Blaauw, Anna Urciuolo, Michela Pozzobon   +20 more
wiley   +1 more source

Automated Optical 3d Scanner to Assess Postoperative Edema Following Forefoot Surgery

Journal of Foot and Ankle Research, Volume 19, Issue 1, March 2026.
ABSTRACT Background Postoperative edema is a common and often underestimated consequence of forefoot surgery, potentially affecting wound healing, patient comfort, and recovery time. Traditional measurement techniques, such as water displacement and circumferential taping, have limitations in the immediate postoperative period due to infection risk and
Julien Beldame, Alessandro Civinini, Marie Aude Munoz, Riccardo Sacco, Amine Hamza, Matthieu Lalevee, Marie‐Anne Melone   +6 more
wiley   +1 more source

Vascular Reconstruction in Extremity Soft Tissue Sarcomas: A Systematic Review and Single‐Arm Meta‐Analysis

Journal of Surgical Oncology, Volume 133, Issue 4, Page 486-510, March 15, 2026.
ABSTRACT Introduction The management of extremity soft tissue sarcomas (STS) involving major vessels presents unique challenges, historically leading to amputation. Advances in vascular reconstruction have enabled limb‐sparing surgery (LSS), but outcomes and perioperative risks remain uncertain.
Lucas Monteiro Delgado, Bernardo Fontel Pompeu, Vinícius dos Santos Macedo, Gabriel Henrique Acedo Martins, Eric Pasqualotto, Matheus Reginato Araujo, Julia Hoici Brunini, Victor Andrade Nunes, Cláudia Theis, Samuel Aguiar Junior   +9 more
wiley   +1 more source

Metastatic Spine Disease Alters Vertebral Load‐To‐Strength Ratios in Cancer Patients Compared to Healthy Individuals

JOR SPINE, Volume 9, Issue 1, March 2026.
This study investigated the effect of spinal bone metastasis (BM) on the biomechanical environment of the spine through estimates of load, strength, and the load‐to‐strength ratio (LSR). Our study suggests that task‐specific differences related to cancer, lesion type, and vertebral location differentially affect the biomechanical environment of the ...
Dennis E. Anderson, Mario Keko, Joanna James, Brett T. Allaire, David Kozono, Patrick F. Doyle, Heejoo Kang, Sarah Caplan, Tracy Balboni, Alexander Spektor, Mai Anh Huynh, Mary L. Bouxsein, David B. Hackney, Ron N. Alkalay   +13 more
wiley   +1 more source

Adenotonsillar Microbiome Shifts in Children With Obstructive Sleep Apnea Syndrome

The Laryngoscope, Volume 136, Issue 3, Page 1525-1535, March 2026.
This study compares the microbiomes of adenoids and tonsils in pediatric OSAS patients and healthy controls using 16S rRNA sequencing. Significant differences were found in the tonsillar microbiome of OSAS patients, with lower alpha diversity and an overrepresentation of pathogenic genera like Haemophilus and Neisseria, while adenoid microbiomes showed
Oded Kraus, Yehuda Schwarz, Yair Motro, Tal Marom, Ron Lamdan, Vadim Kapuller, Sharon Tamir Ovnat, Jacob Moran‐Gilad   +7 more
wiley   +1 more source

Cellulose‐Based Nanocomposites in Drug Delivery and Antimicrobial Therapies: Emerging Innovations and Translational Outlook

MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
Applications of cellulose‐based nanocomposites in antimicrobial drug delivery. ABSTRACT Cellulose‐based nanocomposites have emerged as sustainable and versatile biomaterials with promising applications in drug delivery and antimicrobial therapy.
Suraj Kumar, Rishabha Malviya, Sathvik Belagodu Sridhar, Tarun Wadhwa, Javedh Shareef   +4 more
wiley   +1 more source

Hybrid Probiotic Hydrogel With Curcumin‐Loaded MnO2 Nanoparticles Enhances Diabetic Wound Healing Through Multimodal Microenvironmental Regulation

Rare Metals, Volume 45, Issue 3, March 2026.
ABSTRACT Skin wound injuries are often accompanied by bacterial infections and severe inflammation. Especially, M1‐type macrophages at the wound site can trigger a cascade of inflammatory responses, mediating a vicious cycle of inflammation. Meanwhile, hypoxia further exacerbates vascular damage and constriction in the wound microenvironment, thereby ...
Xianfeng Wang, Yuwen Shangguan, Hao Nan, Lingze Chen, Chencheng Gu, Litao Yan, Huan Li   +6 more
wiley   +1 more source

Multidisciplinary approach to bone metastases: a single center experience in a tertiary cancer center. [PDF]

Support Care Cancer
Pittarello C, Brunello A, Lamberti E, Zovato S, Formaglio F, Galuppo S, Krengli M, Nena U, Angelini A, Ruggieri P, Pozza V, Pintacuda G, Pittaro A, Aldegheri V, Ballestrin M, Roma A, Lonardi S, Guarneri V, Falci C, Maruzzo M.   +19 more
europepmc   +1 more source

Factors associated with flexible cystoscope longevity: an analysis of supplier and health service datasets

BJU International, Volume 137, Issue 3, Page 509-518, March 2026.
Objectives To investigate the associations between how reusable flexible cystoscopes (FCs) are managed during their functioning lifetime and their longevity. Patients and Methods This was an exploratory retrospective analysis of administrative data collected by a medical supplies company (KARL STORZ Endoscopy (UK) Ltd) on FC usage linked at a National ...
Joseph B. John, Robert Feasey, Ranan Dasgupta, Tim W.R. Briggs, John S. McGrath, William K. Gray   +5 more
wiley   +1 more source