Results 221 to 230 of about 39,132 (298)

Genotype–Phenotype Correlations of Li–Fraumeni Syndrome in Japan Children's Cancer Group LFS20 Study Cohort

Cancer Science, Volume 117, Issue 3, Page 836-840, March 2026.
This study investigates genotype–phenotype correlations in Japanese families with germline TP53 pathogenic variants, collected through a nationwide prospective cancer surveillance study (JCCG LFS‐20). Among 41 families analyzed, 36 met criteria for Li–Fraumeni syndrome (LFS), and 5 were classified as attenuated LFS.
Fumito Yamazaki, Yoshiko Nakano, Masashi Sanada, Hiroki Kurahashi, Shunsuke Miyai, Arisa Ueki, Yuko Watanabe, Daisuke Hasegawa, Shuhei Karakawa, Toshifumi Ozaki, Akira Hirasawa, Akiko M. Saito, Eisuke Inoue, Motohiro Kato, Hiroyoshi Hattori   +14 more
wiley   +1 more source

Correction: Differential diagnosis of benign and malignant vertebral compression fractures based on CT radiomics model. [PDF]

Front Oncol
Liu X, Chen S, Wang Y, Cao J, Niu Z, Jin Y, Pan X, Zhang Z, Liu T, Liang W, Yu P, Zou W.   +11 more
europepmc   +1 more source

Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis

Cell Proliferation, Volume 59, Issue 3, March 2026.
In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang, Rui Sun, Zhibin Lan, Qi Ma, Gang Wu, Di Xue, Zhirong Chen, Yajing Su, Ye Ma, Xiaolei Chen, Jiangbo Yan, Long Ma, Xiaoxin He, Kuanmin Tian, Xiaoyi Ma, Xue Lin, Qunhua Jin   +16 more
wiley   +1 more source

Adhesion of Immunoglobulins to Band3 Promotes Increased Erythrocyte Sedimentation Rate in Multiple Myeloma

Cell Proliferation, Volume 59, Issue 3, March 2026.
Decreased sialic acid increases the adhesion of RBC membranes to immunoglobulins leading to an increased erythrocyte sedimentation rate (ESR). The increase in reactive oxygen species (ROS) damages the sialic acid glycosyl chains on the surface of RBC membrane proteins, causing the membrane proteins to be overexposed to the plasma environment due to the
Sicheng Bian, Jiangxia Cui, Xialin Zhang, Chongzhi Bai, Yanhong Tan, Zhuanghui Hao, Xingpeng Bu, Changxin Qu, Lili Sun, Leilei Lin, Qi Wang, Zhengrui Li, Xufeng Huang, Hengrui Liu, Ruo Wang, Yinghua Li, Hongwei Wang   +16 more
wiley   +1 more source

The Contingent Payoff of Transparency: The Mediating Roles of Citizen Participation and Enforcement in Health Service Delivery Improvement

Journal of Evaluation in Clinical Practice, Volume 32, Issue 2, March 2026.
ABSTRACT Background How transparency reforms affect frontline health service delivery remains uncertain. Research presents a transparency paradox, where some studies report service improvements when transparency is combined with oversight, while others find minimal impact on outcomes such as staff absence or medicine availability.
Samuel Atiku, Alfred Okoh, Olufisayo Olakotan   +2 more
wiley   +1 more source

The impact of non-centralised surgical treatment on local recurrence, amputation rate and survival in patients with extremity soft tissue sarcoma. [PDF]

Eur J Orthop Surg Traumatol
Malina M, Švec A, Majerčík M, Bibza M, Tóth Z, Karoľ D, Hudec P, Kocour J, Kokavec M.   +8 more
europepmc   +1 more source

Which Cultural Safety Strategies Are Making a Difference? Exploring Hospital Initiatives for First Nations Peoples in Australia. A Scoping Review

Journal of Clinical Nursing, Volume 35, Issue 3, Page 964-1001, March 2026.
ABSTRACT Aim To explore the barriers, facilitators, and outcomes of strategies that have been implemented to improve the experience of cultural safety for First Nations inpatients in the Australian hospital setting. Design Scoping review. Methods Guided by the Joanna Briggs Institute scoping review methodology and reported using PRISMA‐ScR, six ...
Kate Fowler, Mary O'Loughlin
wiley   +1 more source

Case Report: Multidisciplinary approach for complete resection of primary advanced low-grade serous ovarian carcinoma involving the iliac vessels and paraspinal region. [PDF]

Front Oncol
Ida N, Nagao S, Fujikawa A, Tanaka Y, Tanioka M, Imatani R, Tani Y, Sugihara H, Matsuoka H, Okamoto K, Haraga J, Ogawa C, Nakamura K, Masuyama H.   +13 more
europepmc   +1 more source

Understanding Nurses' and Physicians' Knowledge, Use and Perspectives on Nitrous Oxide/Oxygen Use in Paediatrics: A Cross‐Sectional Study

Nursing in Critical Care, Volume 31, Issue 2, March 2026.
ABSTRACT Background Nitrous oxide/oxygen (N2O/O2 50%/50%) is an effective and safe technique for procedural sedation in paediatric settings; however, the knowledge, use and perspectives of healthcare professionals regarding N2O/O2 remain limited. Aim To investigate the knowledge, use and perspectives of healthcare professionals regarding N2O/O2 in ...
Valentina Simonetti, Beatrice Gullo, Ilenia Stracci, Davide Miniscalco, Elisa Capriotti, Silvia Oroli, Michela Arragoni, Lamberto Manzoli, Giancarlo Cicolini, Dania Comparcini   +9 more
wiley   +1 more source

Artificial Intelligence and Augmented Reality in Orthopedic Surgery: A Narrative Review of Current Applications and Future Directions. [PDF]

Cureus
Luigi-Martínez HE, Layuno-Matos JG, Fernández-Vélez NA, Fernández-Soltero R, Señeriz-Ortiz R.   +4 more
europepmc   +1 more source