Results 31 to 40 of about 39,132 (298)

Protein and Signaling Pathway Responses to rhIL-6 Intervention Before Lobaplatin Treatment in Osteosarcoma Cells

open access: yesFrontiers in Oncology, 2021
Lobaplatin is a third-generation platinum-based antineoplastic agent and is widely used for osteosarcoma treatment before and after tumor removal. However, treatment failure often results from lobaplatin drug resistance.
Huan Wang   +7 more
doaj   +1 more source

Variability in the reported management of pulmonary metastases in osteosarcoma. [PDF]

open access: yes, 2015
Nearly 20% of patients with newly diagnosed osteosarcoma have detectable metastases at diagnosis; the majority of which occur in the lungs. There are no established recommendations for the timing and modality of metastasectomy.
Bhattasali, Onita   +6 more
core  

Bone: Osteoblastoma [PDF]

open access: yes, 2010
Review on Bone: Osteoblastoma, with data on clinics, and the genes ...
de, Andrea CE, Hogendoorn, PCW
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Polypropylene Surgical Meshes in Orthopedic Surgery: A Narrative Review [PDF]

open access: yesModern Medicine
Restoring the continuity of the anatomical layers and the musculoskeletal soft tissues is fundamental in the reconstructive phases of all surgical procedures.
Edoardo IPPONI   +6 more
doaj   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1977
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1140/thumbnail ...

core   +1 more source

Increased risk for other cancers in individuals with Ewing sarcoma and their relatives. [PDF]

open access: yes, 2019
BackgroundThere are few reports of the association of other cancers with Ewing sarcoma in patients and their relatives. We use a resource combining statewide genealogy and cancer reporting to provide unbiased risks.MethodsUsing a combined genealogy of 2 ...
Abbott, Diana   +9 more
core   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas   +7 more
wiley   +1 more source

Predictive Modeling for Spinal Metastatic Disease

open access: yesDiagnostics
Spinal metastasis is exceedingly common in patients with cancer and its prevalence is expected to increase. Surgical management of symptomatic spinal metastasis is indicated for pain relief, preservation or restoration of neurologic function, and ...
Akash A. Shah, Joseph H. Schwab
doaj   +1 more source

Patient-Reported Outcomes Measurement Information System physical function correlates with Toronto Extremity Salvage Score in an orthopaedic oncology population [PDF]

open access: yes, 2019
Background: The National Institute of Health\u27s Patient-Reported Outcomes Measurement Information System (PROMIS) uses computerised-adaptive testing to reduce survey burden and improve sensitivity.
Calfee, Ryan P   +5 more
core   +1 more source

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