Results 91 to 100 of about 221,706 (315)

Dopamine D1 Receptor Contributes to Glucocorticoid‐Associated Osteonecrosis of Femoral Head Protection Through the ATF3/CHOP Axis to Inhibit Osteoblastic Apoptosis

Advanced Science, EarlyView.
This work identifies a novel mechanism by which dopamine D1 receptor (DRD1) contributes to the pathogenesis of glucocorticoid (GC)‐associated osteonecrosis of the femoral head (ONFH) through the regulation of osteoblastic apoptosis, indicating that DRD1 serves as a critical mediator of the crosstalk between the nervous and skeletal systems.
Kai Zheng, Wenming Li, Tianhao Wang, Gaoran Ge, Wei Zhang, Yi Qin, Wenhao Li, Zebin Wu, Zhen Wang, Gang Rui, Yaozeng Xu, Dechun Geng   +11 more
wiley   +1 more source

Evaluation of Absolute Neutrophil Count in the Perioperative Setting of Sarcoma Resection

Advances in Orthopedics
Introduction. Limb salvage surgery (LSS) is the preferred surgical treatment for bone sarcomas. Preoperatively, many patients receive chemotherapy and may develop neutropenia.
Gayathri Vijayakumar, Emma M. Steffer, Neil P. Buac, Matthew W. Colman, Steven Gitelis, Alan T. Blank   +5 more
doaj   +1 more source

Orthopedic Surgery For Nurses [PDF]

, 1916
John M. Berry
openalex   +1 more source

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

Advanced Science, EarlyView.
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei, Yihan Wang, Jingxia Chen, Jing Zhou, Yuzhu Han, Xiuyu Liu, Siyu Chen, Sheng Chen, Dixin He, Yunxiao Wu, Huixin Lv, Yanmin Zhou   +11 more
wiley   +1 more source

A Case of Neglected Posterior Fracture Dislocation of the Shoulder Treated With Greater Tuberosity Osteotomy

Case Reports in Orthopedics
Posterior dislocation of the shoulder joint is a rare condition. It is often misdiagnosed owing to a lack of evident clinical features compared with anterior shoulder dislocation, and inappropriate radiological examination.
Masashi Koide, Satoshi Tateda, Sayaka Miyasaka, Akihiro Yasuyama, Yoichi Sasaki, Mika Abe   +5 more
doaj   +1 more source

Full-endoscopic Spine Surgery for the Treatment of Lumbar Ligamentous Flavum Hematoma

Neurologia Medico-Chirurgica
Lumbar ligamentous flavum hematoma (LFH) is a relatively rare pathology, and it is difficult to differentiate it from other cystic lesions. Full-endoscopic spine surgery (FESS), an excellent approach for clear and magnified operative visual field since ...
Chia-Wei CHANG, Ryoji TOMINAGA, Yasushi OSHIMA, Hiroki IWAI, Hirohiko INANAMI, Hisashi KOGA   +5 more
doaj   +1 more source

Third Report in Orthopedic Surgery [PDF]

, 1913
ROBERT B. OSGOOD, Robert Soutter, Hermann Bucholz, Murray S. Danforth   +3 more
openalex   +1 more source

Glucose‐Responsive PAGR1‐Regulated Skeletal Muscle Gene Program Controls Systemic Glucose Homeostasis and Hepatic Metabolism

Advanced Science, EarlyView.
The study reveals that PAXIP1‐associated glutamate‐rich protein 1 (PAGR1), a glucose‐responsive regulator in skeletal muscle, modulates systemic glucose homeostasis and hepatic metabolism. Muscle‐specific PAGR1 deletion enhances insulin signaling, promotes glucose transporter 4 (GLUT4) translocation, and protects against high‐fat‐diet‐induced insulin ...
Chenyun Ding, Yuhuan Jia, Lin Liu, Wen Wang, Danxia Zhou, Zheng Zhou, Likun Yang, Xinyi Chen, Di Chen, Yan Mao, Liwei Xiao, Cai‐Zhi Liu, Zhen‐Yu Du, Yujing Yin, Qiqi Guo, Zongchao Sun, Kai Ge, Tingting Fu, Hai‐Long Piao, Zhenji Gan   +19 more
wiley   +1 more source

Pathology in Its Relation to Orthopedic Surgery [PDF]

, 1898
Robert W. Lovett
openalex   +1 more source

Adipocytes Promote Cisplatin Resistance through Secreting A1BG and Regulating NAMPT/PARP1 Axis‐Mediated DNA Repair in Osteosarcoma

Advanced Science, EarlyView.
The proposed working model for how adipocytes participate in cisplatin resistance in osteosarcoma. The adipocytes secret A1BG and stabilize NAMPT, leading to increased NAD⁺ levels and subsequent increased PARP1‐mediated DNA repair, resulting in cisplatin resistance in osteosarcoma finally.
Yonghui Liang, Zhaohui Li, Lina Tang, Zhen Pan, Xiang Fei, Chen Tan, Aina He, Qingcheng Yang, Dongdong Cheng   +8 more
wiley   +1 more source