The G‐CS/MSN drug delivery system enhances intervertebral disc repair through sequential drug release. Abstract Intervertebral disc degeneration (IDD) is characterized by an inflammatory environment and dysregulation of the extracellular matrix metabolism (ECM).
Xiangzhen Kong+12 more
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Magnetically guided bioceramic nanoparticles (“CalBots”) achieve deep dentinal tubule occlusion via directed self‐assembly under externally applied magnetic field. Various visualization techniques and a novel mouse behavioral assay indicate that CalBot‐induced plugs may reduce dentinal sensitivity, offering a promising strategy for future dentin ...
Shanmukh Peddi+6 more
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Tendon Aging: A Silent Enemy Revealed Strategies for Effective Treatment
This review commences with the mechanism of tendon aging, mainly introducing the aging of tendons induced by oxidative stress, hyperglycemia, inflammatory response, cell apoptosis, and fatty infiltration and the association with the tendon stem/progenitor cells, aiming to explore the mechanism of aging and find related treatment methods.
Wenhui Gu+3 more
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On the Contributions of Hugh Owen Thomas of Liverpool, Sir Robert Jones of Liverpool and London, John Ridlon, M.D., of New York and Chicago to Modern Orthopedic Surgery [PDF]
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This study aimed to clarify the epidemiology of hemorrhoids by leveraging a comprehensive nationwide healthcare claims database in Japan. By analyzing invasive treatments for hemorrhoids over a 5‐year period (2018–2022), we identified key demographic patterns, including distinct bimodal peaks in incidence among males and females, and highlighted ...
Masamitsu Kido+8 more
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Magnetic soft robots offer promise in biomedicine due to their wireless actuation and rapid response, but current fabrication methods are complex and have limited cellular compatibility. A new, contactless bioassembly strategy using hydrodynamic instabilities is introduced, enabling customizable, centimeter‐scale robots.
Wei Gao+5 more
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Symposia for orthopedic surgeons. I. Practical Surgery of the Hand, edited by Martin A. Entin, M.D., C.M.; 2. Joint, Bone and Muscle Disorders, edited by Edward F. Rozenberg, M.D., F.A.C.P.; 3. Surgery of the Lower Extremity, edited by Harold A. Sofield, M.D., F.A.C.S. Reprinted from the Surgical and Medical Clinics of North America. 9 × 5g¾ in. Pp. 820, with 343 illustrations. 1965. Philadelphia and London: W. B. Saunders Company. £5 5s [PDF]
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ABSTRACT Chondrocalcinosis (CCAL), also known as calcium pyrophosphate dihydrate deposition disease (CPPDD), is a frequent multifactorial condition in the elderly, but there are two rare autosomal dominant Mendelian forms, CCAL1 (OMIM %600668) and CCAL2. Only three families with molecularly proven CCAL1 have been reported.
Anna‐Christina Pansa+4 more
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Orthopedics‐principles and their application. By Samuel L. Turek, M.D., Assbtant Attending Orthopedic Surgeon, Mount Sinai Hospital, Miami Beach, Florida; fwmerly Attending Orthopedic Surgeon, Webs Memorial Hospital, Chicago; Instructor, Department of Orthopedic Surgery, Northwestern Uniuersity Medical School. Philadelphia, Lippincott, 1967. 996 pages; 1 0 × 7″ (25 × 17.5 cm.). 658 illrrstrations. $27.00 [PDF]
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