Results 121 to 130 of about 360,787 (305)

Brief History of Spinal Neurosurgical Societies in the United States: Part 1. [PDF]

open access: yes, 2019
Ames, Christopher P.   +7 more
core   +2 more sources

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

open access: yesAdvanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao   +8 more
wiley   +1 more source

Early efficacy observation of the unilateral biportal endoscopic technique in the treatment of multi-level lumbar spinal stenosis

open access: yesJournal of Orthopaedic Surgery and Research
Background To explore the early curative effect of unilateral biportal endoscopy (UBE) in the treatment of multi-level lumbar spinal stenosis with the help of multiple small incisions.
Dingding Jia   +6 more
doaj   +1 more source

Full-endoscopic Spine Surgery for the Treatment of Lumbar Ligamentous Flavum Hematoma

open access: yesNeurologia Medico-Chirurgica
Lumbar ligamentous flavum hematoma (LFH) is a relatively rare pathology, and it is difficult to differentiate it from other cystic lesions. Full-endoscopic spine surgery (FESS), an excellent approach for clear and magnified operative visual field since ...
Chia-Wei CHANG   +5 more
doaj   +1 more source

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

open access: yesAdvanced Science, EarlyView.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang   +13 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1980
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1176/thumbnail ...

core   +1 more source

A Photothermal Transducer Regulates Transmembrane Calcium Flow for Synergistic Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
Upon NIR irradiation at 808 nm, the activity of TRPV4 was inhibited by M2M@BPSC, which led to reduced calcium influx, mitochondrial protection, and, importantly, the transcriptional activation of the STAT6‐EGR2 pathway. The improved macrophage function indirectly readjusts the equilibrium between C‐ECM and F‐ECM to reconstruct a suitable ...
Chenqi Yu   +11 more
wiley   +1 more source

Comparison of Surgical Outcomes of the Posterior and Combined Approaches for Repair of Cervical Fractures in Ankylosing Spondylitis. [PDF]

open access: yes, 2019
STUDY DESIGN: Retrospective cohort study. PURPOSE: To evaluate surgical outcomes and complications of cervical spine fractures in ankylosing spondylitis (CAS) patients who were treated using either the posterior (P) or combined approach (C).
Ariyawatkul, Thanase   +5 more
core   +1 more source

Self‐Adaptive Allantoin@ZIF8 Nanocomposite Hydrogel with Resveratrol Synergy for MRSA‐Infected Wound Regeneration

open access: yesAdvanced Science, EarlyView.
Based on allantoin‐loaded ZIF8 nanoparticles (Alla@ZIF8) and methacrylated quaternary ammonium carboxymethyl chitosan/resveratrol composite hydrogels (RMQCC), an adaptive multifunctional hydrogel system (Alla@ZIF8‐Gel) was constructed and confirmed to induce the healing of MRSA‐infected wounds via suppressing bacterial proliferation, alleviating ...
Yongjie Zhu   +8 more
wiley   +1 more source

Patellar Instability: A Narrative Review with an Integrated Treatment Algorithm

open access: yesOrthopedic Research and Reviews
Joseph Mouawad,1,2 Joeffroy Otayek,1,2 Youssef Jamaleddine,1,2 Theodore Kaypekian,1,2 Mohamad Omar Youssef Honeine,1,2 Alfred Khoury1,2 1Department of Orthopedic Surgery, Lebanese American University Medical Center-Rizk Hospital, Beirut, Lebanon ...
Mouawad J   +5 more
doaj  

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