Orthopädie und Kinderlähmung (Orthopedics and Infantile Paralysis) [PDF]
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PROMIS and FAAM Minimal Clinically Important Differences in Foot and Ankle Orthopedics
Background: Establishing score points that reflect meaningful change from the patient perspective is important for interpreting patient-reported outcomes.
Man Hung+5 more
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Osteoblast‐CD4+ CTL Crosstalk Mediated by SIRT1/DAAM2 Axis Prevents Age‐Related Bone Loss
In the osteoblastic niche, SIRT1 activates and recruits CD4+ CTLs by increasing DAAM2 expression via EZH2 deacetylation and boosting the secretion of key chemokines, such as CCL3, CCL5, and CXCL10. Then, CD4+ CTL directly eliminates senescent osteoblasts in an MHC‐II‐dependent way, thereby slowing down the process of bone ageing and effectively ...
Bin Yang+20 more
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Orthopedics for the General Practitioner [PDF]
William E. Kenney, Carroll B. Larson
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Oxygen‐releasing immunomodulatory microspheres are used to construct conformal bone organoid units that enhance osteogenesis, angiogenesis, and immune regulation. By integrating BMSCs, macrophages, and CaO₂‐HAp into a SilMA‐based hydrogel platform, this strategy provides sustained oxygen supply and anti‐inflammatory microenvironments, leading to ...
Anfu Deng+12 more
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Digital orthopedics: the third technological wave of orthopedics
As an emerging interdisciplinary field, digital orthopedics is hailed as the third technological wave in orthopedics, with its applications gradually expanding into various areas and continuously innovating orthopedic clinical practice.
Jiayao Zhang, Zhewei Ye
doaj
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie+8 more
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Pinosylvin Inhibits Inflammatory and Osteoclastogenesis via NLRP3 Inflammasome
Pinosylvin blocks LPS and RANKL induced NEK7/NLRP3 interaction, inhibiting NLRP3 inflammasome oligomerization and assembly, reducing IL‐1β maturation and GSDMD cleavage, and improving the inflammatory microenvironment and abnormal osteoclastogenesis. Abstract Pro‐inflammatory cytokines such as TNF, IL‐1, and IL‐6 trigger aberrant osteoclastogenesis and
Wei Zhang+13 more
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Orthopedics‐principles and their application. By Samuel L. Turek, M.D., Assbtant Attending Orthopedic Surgeon, Mount Sinai Hospital, Miami Beach, Florida; fwmerly Attending Orthopedic Surgeon, Webs Memorial Hospital, Chicago; Instructor, Department of Orthopedic Surgery, Northwestern Uniuersity Medical School. Philadelphia, Lippincott, 1967. 996 pages; 1 0 × 7″ (25 × 17.5 cm.). 658 illrrstrations. $27.00 [PDF]
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