Results 101 to 110 of about 215,550 (286)

CNN Attention Guidance for Improved Orthopedics Radiographic Fracture Classification

open access: yes, 2022
CNN Attention Guidance for Improved Orthopedics Radiographic Fracture ...
JW Verjans (18116032)   +8 more
core  

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

open access: yesAdvanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong   +17 more
wiley   +1 more source

Myofunctional Therapy and the Practice of Gnathologic Orthopedics

open access: yes, 1984
The practice of gnathologic orthopedics en­compasses many disciplines in dentistry [...
Jack Hockel
core   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Orthopedics Outpatient Department

open access: yes, 1948
Doctor Robert W. Maher of Bowman Gray School of Medicine, checks a patient's leg cast during a checkup visit to the Orthopedics Outpatient Department in 1948.Published in 1948 Gray and White Matter ...

core  

2008 Chatham Orthopedics Volleyball Classic: Day Two Wrapup [PDF]

open access: yes, 2008
2008 Chatham Orthopedics Volleyball Classic: Day Two Wrapup. Saint Leo was the only team to remain unscathed after the final day of action at the 2008 Chatham Orthopedics Volleyball Classic, while the host Armstrong Atlantic State Pirates split matches ...
Armstrong State University
core  

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

open access: yesAdvanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang   +10 more
wiley   +1 more source

WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via M6A‐Mediated Regulation of CSF1R Signaling in Estrogen‐Deficient Osteoporosis

open access: yesAdvanced Science, EarlyView.
Scheme of the KLF9/WTAP/YTHDF2/m6A/CSF1R regulatory axis in osteoclastogenesis and estrogen‐deficient osteoporosis. WTAP‐mediated m6A modification of Csf1r mRNA governs osteoclastogenesis via a YTHDF2‐mediated pathway. Pathological upregulation of KLF9 drives Wtap transcription, leading to increased m6A deposition on the 3’‐UTR of Csf1r mRNA.
Chen Shen   +14 more
wiley   +1 more source

80. Emergency Orthopedics Handbook.

open access: yes, 2019
Emergency Orthopedics Handbook, edited by Daniel Purcell, et al., Springer, 2019. ProQuest Ebook Central, http://ebookcentral.proquest.com/lib/polije-ebooks/detail.action?docID=5746924.

core  

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang   +12 more
wiley   +1 more source

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