A therapeutic strategy is proposed for periodontitis using extracellular vesicles derived from EPO‐stimulated macrophages (EPO‐EVs). This schema demonstrates how EPO‐EVs enhance the osteogenic activity of mBMSCs in an inflammatory environment by inhibiting EGFR.
Shuchen Liu+10 more
wiley +1 more source
Partial-to-Full Registration based on Gradient-SDF for Computer-Assisted Orthopedic Surgery [PDF]
In computer-assisted orthopedic surgery (CAOS), accurate pre-operative to intra-operative bone registration is an essential and critical requirement for providing navigational guidance. This registration process is challenging since the intra-operative 3D points are sparse, only partially overlapped with the pre-operative model, and disturbed by noise ...
arxiv
This study presents 3D‐printed Ti‐6Al‐4V trabecular scaffolds combined with hypoxia‐induced exosomes encapsulated in PEGDA/GelMA microspheres for sustained release. The scaffolds mimic the structure of natural bone, while the exosome delivery system enhances osteogenesis and angiogenesis, significantly promoting bone regeneration and offering a ...
Lincong Luo+14 more
wiley +1 more source
Orthopedics‐principles and their application. By Samuel L. Turek, M.D., Assbtant Attending Orthopedic Surgeon, Mount Sinai Hospital, Miami Beach, Florida; fwmerly Attending Orthopedic Surgeon, Webs Memorial Hospital, Chicago; Instructor, Department of Orthopedic Surgery, Northwestern Uniuersity Medical School. Philadelphia, Lippincott, 1967. 996 pages; 1 0 × 7″ (25 × 17.5 cm.). 658 illrrstrations. $27.00 [PDF]
openalex +1 more source
BMSCmotif+miR874/MS system is designed as a gene delivery platform utilizing engineered bone marrow mesenchymal stem cell (BMSC)‐derived extracellular vesicles (EVs) for intercellular communication to achieve sustained delivery of miRNA‐874‐3p. Rejuvenation of chondrocytes and promotion of chondrogenesis are achieved by inhibition of the NF‐κB pathway,
Yuezhou Wu+7 more
wiley +1 more source
Dissociation Between the Growing Opioid Demands and Drug Policy Directions Among the U.S. Older Adults with Degenerative Joint Diseases [PDF]
We aim to examine temporal trends of orthopedic operations and opioid-related hospital stays among seniors in the nation and states of Oregon and Washington where marijuana legalization was accepted earlier than any others.
Bahta, Tsigab, MD+16 more
core +1 more source
1975 Year book of orthopedics and traumatic surgery. Edited H. Herman Young. 190 × 13O mm. Pp. 477, with 171 illustrations. 1975. London: Lloyd-Luke. £11·70 [PDF]
R B Duthie
openalex +1 more source
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang+11 more
wiley +1 more source
The Evaluation of Magnetic Resonance Imaging Application in Treatment of Tumors in Orthopedics [PDF]
Han Koo Lee+5 more
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