Editor’s Letter. Use of computational simulation by Finite Element Method in Jaw Functional Orthopedics. Is it possible and feasible? [PDF]
Orlando Espinosa Santiago
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This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi +11 more
wiley +1 more source
Antisepsis Techniques in Orthopedic Surgical Procedures: A Comparative Study
Objective To compare antisepsis techniques using chlorhexidine-based soap associated with ethyl alcohol and alcohol-based chlorhexidine or chlorhexidine-based soap associated with alcohol-based chlorhexidine alone in surgical orthopedic procedures ...
Eugênio César Mendes +5 more
doaj +1 more source
RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song +11 more
wiley +1 more source
Orthopedics in Primary Care, 3rd edition, 1999Orthopedics in Primary Care, 3rd edition, 1999 Edited by GeraldSteinbergCarltonAkins and DanielBaran. Publishers: Lippincott Williams & Wilkins, 227 East Washington Square, Philadelphia, PA 19106-3780. Price: $69.95 ISBN: 0-683-30258-2 [PDF]
Paul Moreau
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GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
An evidence-based evaluation on the use of platelet rich plasma in orthopedics – a review of the literature [PDF]
Nasir Hussain +2 more
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A schematic diagram of the mechanism where small extracellular vesicles mediate the enhancement of heterotopic wound healing by radial extracorporeal shockwave stimulation at a proximal tibial osteotomy site. ABSTRACT Wound healing represents a complex biological process necessitating innovative therapeutic approaches, particularly for chronic wounds ...
Xiaoping Xie +8 more
wiley +1 more source
Effect of low temperatures on osserous and cartilaginous tissues [PDF]
The use of extreme cold to treat tumoral afflictions of the extremities is discussed. Cryogenic methods and instruments are discussed, and the levels of accumulated knowledge in this area (as well as the areas still in question) are evaluated.
Babiychuk, G. A. +3 more
core +1 more source
Purpose: Different deep-learning models have been employed to aid in the diagnosis of musculoskeletal pathologies. The diagnosis of tendon pathologies could particularly benefit from applying these technologies.
Guillermo Droppelmann +4 more
doaj +1 more source

