Results 121 to 130 of about 250,574 (293)

Effectiveness of dry needling combined with eccentric strength training in lateral epicondylalgia with trigger points

Physiotherapy Quarterly
Introduction Lateral epicondylalgia (LE) is commonly presented with myofascial trigger points (MTrPs) among adults. Dry needling (DN) is used less frequently as a first-line treatment in LE with trigger points, and the short and long-term effectiveness ...
Sukumar Shanmugam, Lawrence Mathias, Ramprasad Muthukrishnan, Praveen Kumar Kandakurti, Satheeskumar Durairaj   +4 more
doaj   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Orthobiologic Management Options for Degenerative Disc Disease

Bioengineering
Degenerative disc disease (DDD) is a pervasive condition that limits quality of life and burdens economies worldwide. Conventional pharmacological treatments primarily aimed at slowing the progression of degeneration have demonstrated limited long-term ...
Cezar Augusto Alves de Oliveira, Bernardo Scaldini Oliveira, Rafael Theodoro, Joshua Wang, Gabriel Silva Santos, Bruno Lima Rodrigues, Izair Jefthé Rodrigues, Daniel de Moraes Ferreira Jorge, Madhan Jeyaraman, Peter Albert Everts, Annu Navani, José Fábio Lana   +11 more
doaj   +1 more source

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

Advanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song, Zuomeng Wu, Yixiang Dong, Yunxiong Fang, Shiyu Bian, Daokuan Wang, Huang Fang, Yunlei Liu, Wang Ying, Jun Qian, Tianyu Han, Cailiang Shen   +11 more
wiley   +1 more source

Occupational therapy\u27s link to vocational reeducation, 1910-1925. [PDF]

, 1997
The development of occupational therapy is rooted in early 20th century medical reform. During the early 1910s, several members of the medical profession, human service workers, and the larger American society were increasingly disturbed by medical ...
Gutman, Sharon A
core   +1 more source

An evidence-based evaluation on the use of platelet rich plasma in orthopedics – a review of the literature [PDF]

, 2017
Nasir Hussain, Herman Johal, Mohit Bhandari   +2 more
openalex   +1 more source

USE OF THE INTERNET AND SOCIAL NETWORKS IN ORTHOPEDICS AND TRAUMATOLOGY AND PERSPECTIVE OF POST COVID TELEMEDICINE [PDF]

, 2022
ALEXANDRE RAMOS ESTANISLAU, Daniel Magalhães Nobre, FILIPE DIAS NASSAR NABACK, Tomás Santos Vasconcelos Barros, LUIZ FELIPE MUNDIM DE SOUZA, Pedro Cid Loureiro Penido   +5 more
openalex   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Mesenchymal Stem Cells—A Boon to Orthopedics

, 2018
R Ramesh, Madhan Jeyaraman, Kartavya Chaudhari, Hardik J. Dhamsania, Gollahalli Shivashankar Prajwal   +4 more
openalex   +2 more sources

Better recognition of orthopedics, traumatology and sports medicine in the system of journal ranking [PDF]

, 1998
Pekka Kannus, Markku Järvinen
openalex   +1 more source