Results 121 to 130 of about 224,709 (317)
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source
The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang+6 more
wiley +1 more source
Language Skills of Young Children With Unilateral Cleft Lip and Palate Following Infant Orthopedics: A Randomized Clinical Trial [PDF]
Emmy M. Konst+3 more
openalex +3 more sources
An Optimization-based Baseline for Rigid 2D/3D Registration Applied to Spine Surgical Navigation Using CMA-ES [PDF]
A robust and efficient optimization-based 2D/3D registration framework is crucial for the navigation system of orthopedic surgical robots. It can provide precise position information of surgical instruments and implants during surgery. While artificial intelligence technology has advanced rapidly in recent years, traditional optimization-based ...
arxiv
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie+8 more
wiley +1 more source
Gut metabolite trimethylamine N‐oxide accumulates in the diabetic wound area to amplify macrophage inflammation via enhancing glycolysis activities. Kinsenoside induces macrophage repolarization from M1 to M2 phenotype through inhibiting IRE1α/XBP1 pathway, followed by HIF‐1α‐glycolysis axis repression and mitophagy‐oxidative phosphorylation axis ...
Li Lu+13 more
wiley +1 more source
Avicenna’s Views on Bone Fractures in Canon of Medicine
The human knowledge on orthopedics traces back to dawn of the medical history. During the history of medicine, several scholars including Persian scientists investigated orthopedics and contributed to its flowering.
Mohammad Kalantari Meibodi+3 more
doaj
Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang+16 more
wiley +1 more source
SOME ASPECTS OF ORGANIZATION OF HIGH TECHNOLOGY MEDICAL AID RENDERING AT SARATOV SCIENTIFIC RESEARCH INSTITUTE OF TRAUMATOLOGY AND ORTHOPEDICS [PDF]
The article is devoted to the peculiarities of organization of high technology medical aid rendering at Saratov Scientific Research Institute of Traumatology and Orthopedics.
T.A. Shulgina+7 more
doaj