Results 41 to 50 of about 201,296 (289)

Data of knee arthroplasty register of Vreden Russian Research Institute of Traumatology and Orthopedics for period 2011-2013

open access: yes, 2015
The knee arthroplasty register was established in Vreden Russian Research Institute of Traumatology and Orthopedics on 01.01.2011 and during the following 3 years the data about 6530 primary (91,7%) and revision (8,3%) cases were collected.
T. A. Kulyaba   +7 more
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

open access: yesAdvanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou   +23 more
wiley   +1 more source

Sportorthopädie | Sports Orthopedics

open access: yesDeutsche Zeitschrift für Sportmedizin, 2018
Optimizing precision and efficacy of measures on the individual level beyond what is achievable based on group means is the characterizing aim of personalized medicine. Sports medicine is a promising field of application for this concept and some aspects
Hecksteden A, Meyer T
doaj   +3 more sources

Intra- and inter-observer reliability of Dias-Tachdjian classification in pediatric ankle fractures: do clinical experience and expertise matter?

open access: yes, 2023
TheDias-Tachdjian classificationis the most commonly used system for the classification of pediatric ankle fractures, but its inter- andintra-observer reliabilityhas not been studied in detail.
Kendirci, Alper Şükrü   +19 more
core   +1 more source

3D Large‐Scale Subwavelength‐Resolution Sound Sheet Tomography Based on an Active and Programmable Circular Meta‐Array

open access: yesAdvanced Science, EarlyView.
A programmable 2048‐element circular ultrasound array combined with a compact acoustic lens produces a thin “sound sheet” over a large field of view, and records echoes with wide angular diversity across the ring aperture. Coherence‐enhanced beamforming converts full‐matrix data into high‐contrast tomographic slices, delivering near‐diffraction‐limited
Qiu‐De Zhang   +11 more
wiley   +1 more source

New Year’s greeting and overview of World Journal of Orthopedics in 2021

open access: yes, 2021
On behalf of the Editorial Office of World Journal of Orthopedics (WJO), we extend our sincere gratitude to our authors, subscribers, readers, Editorial Board members, and peer reviewers, thanking each and every one for their contributions to WJO in 2020
Wang J. -L., Leigheb M.
core   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

open access: yesAdvanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng   +15 more
wiley   +1 more source

Osteocondrite dissecante em côndilo femural lateral bilateral nos joelhos

open access: yes, 2013
The osteochondritis dissecans (OCD) is a disease of unknown cause that classically affects the knee lateral border of the medial femoral condyle. We present a rare case of OCD in bilateral lateral femoral condyle.A osteocondrite dissecante (OCD) é uma ...
Filho, Mario Carneiro   +9 more
core   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

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