Results 41 to 50 of about 219,843 (239)

Digital orthopedics: the third technological wave of orthopedics

open access: yesIntelligent Medicine
As an emerging interdisciplinary field, digital orthopedics is hailed as the third technological wave in orthopedics, with its applications gradually expanding into various areas and continuously innovating orthopedic clinical practice.
Jiayao Zhang, Zhewei Ye
doaj   +1 more source

Role of orthopedics in the fight against COVID-19 [PDF]

open access: yes, 2020
Role of orthopedics in the fight against COVID ...
Enrique Armando Pancorbo Sandoval
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Artificial intelligence in traumatology and orthopedics. Reality, fantasy or false hopes? [PDF]

open access: yes
Background. In recent years, the topic of artificial intelligence (AI) in medicine has been actively discussed not just as a promising solution but the one that can help to improve some results. A significant growth of interest in AI systems all over the
Cherny A.A.   +5 more
core   +2 more sources

Osteocondrite dissecante em côndilo femural lateral bilateral nos joelhos [PDF]

open access: yes, 2013
The osteochondritis dissecans (OCD) is a disease of unknown cause that classically affects the knee lateral border of the medial femoral condyle. We present a rare case of OCD in bilateral lateral femoral condyle.A osteocondrite dissecante (OCD) é uma ...
Ricardo Soares da Silva   +7 more
core   +1 more source

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

open access: yesAdvanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li   +4 more
wiley   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

open access: yesAdvanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng   +9 more
wiley   +1 more source

Clinical Institute: Orthopedics & Sports Medicine

open access: yes, 2018
Orthopedics and Sports Medicine Clinical Institutehttps://digitalcommons.providence.org/homepage-slideshow/1004/thumbnail ...

core   +1 more source

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

open access: yesAdvanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang   +7 more
wiley   +1 more source

Neonatal Maxillary Orthopedics: Past to Present

open access: yes, 2012
Neonatal maxillary orthopedics was introduced in the treatment protocol for cleft lip and palate in the 1950s of the last century. A wide range of appliances has been designed with pin-retained active appliances at one end of the spectrum and passive ...
Prahl, C.   +3 more
core   +2 more sources

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