Results 61 to 70 of about 201,296 (289)

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

open access: yesAdvanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu   +7 more
wiley   +1 more source

Perineural Dexamethasone is More Efficient Than Perineural Dexmedetomidine in Prolonging Popliteal Sciatic and Saphenous Nerve Blocks: A Single-Center, Prospective, Double-Blinded, Randomized Controlled Trial

open access: yesLocal and Regional Anesthesia
Guiyu Lei,1 Lili Wu,1 Yue Yin,1 Shu Zhang,2 Guyan Wang1 1Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, People’s Republic of China; 2Center of Foot and Ankle Surgery, Beijing Tongren Hospital, Capital
Lei G, Wu L, Yin Y, Zhang S, Wang G
doaj  

Telemedicine in orthopedics

open access: yes, 2011
Orthopedics is a hands-on specialty requiring direct physical contact between the practitioner and the patient. This is true in all orthopedic settings, including outpatients, surgery, trauma and emergency, and rehabilitation.
Russell, Trevor, Hoffmann, Tammy
core  

Gene Therapy in Pediatric Orthopedics

open access: yes
Gene therapy is gaining traction as an effective treatment for several deleterious disorders by delivering genetic material using viral or non-viral vectors to correct mutated genes.
Robin Olaonipekun   +5 more
core   +1 more source

Orthopedics and COVID-19: Scientific Publications Rush

open access: yes, 2020
Background The purpose of this literature review is to analyze all the articles related to COVID-19 and orthopedics and to shed light on the scientific evidence that has actually been found.
D'Ambrosi, Riccardo
core   +1 more source

Custom-Made 3D-Printed Implants for Anterior Column Reconstruction in the Upper Cervical Spine after Intralesional Extracapsular Excision—Report of 2 Cases and Literature Review

open access: yes, 2022
The use of three-dimensional (3D)-printed custom-made implants is spreading in the orthopedics field for the reconstruction of bone losses or for joint replacement, thanks to their unparalleled versatility.
Marco Girolami   +31 more
core   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

open access: yesAdvanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo   +11 more
wiley   +1 more source

Multimodal Synergistic Strategies for Diabetic Wound Healing Using Glucose Oxidase Nanocomposites: Therapeutic Mechanisms and Nanomaterial Design

open access: yesInternational Journal of Nanomedicine
Zaiwei Fan,1,* Chengzhi Liang,1,* Jiayu Zhang,2,* Yiming Li,3,* Lihua Tan,1 Hui Deng,1 Pinkai Wang,1 Jialiang Wang,1 Jiawei Kang,1 Yudan Zhu,1 Hang Fu,1 Jun Tao1 1Department of Orthopedics, The Second Affiliated Hospital ...
Fan Z   +11 more
doaj  

Current Diagnosis and Treatment in Orthopedics

open access: yes, 2000
iii.758 hal.;ill.; 24 ...
Current
core  

Myofunctional Therapy and the Practice of Gnathologic Orthopedics

open access: yes, 1984
The practice of gnathologic orthopedics en­compasses many disciplines in dentistry [...
Jack Hockel
core   +1 more source

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