Results 71 to 80 of about 215,550 (286)

Programmable Encapsulation Enables On‐Demand Proliferation of Therapeutic Bacteria for Potent Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang, Ao Peng, Shuaiqiang Li, Yaning Huang, Jian Yan, Leyuan Wang, Zhihui Zhu, Fei‐Long Liu, Erbao Bian, Yang Liu, Dasheng Tian, Fenghe Li, Qi Liu   +12 more
wiley   +1 more source

Identification of Potential Targets for EGFR-Regulated Nucleus Pulposus Degeneration Using Single-Cell RNA Sequencing and Machine Learning

Journal of Inflammation Research
Xiaoyao Peng,1,* Yi Wang,2,* Yangyang Chen,3 Yuxiang Hu,1 Fashuai Wu,1 Lu Zhang,4 Weihua Xu,1 Yulong Wei1 1Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei ...
Peng X, Wang Y, Chen Y, Hu Y, Wu F, Zhang L, Xu W, Wei Y   +7 more
doaj  

Telemedicine in orthopedics

, 2011
Orthopedics is a hands-on specialty requiring direct physical contact between the practitioner and the patient. This is true in all orthopedic settings, including outpatients, surgery, trauma and emergency, and rehabilitation.
Russell, Trevor, Hoffmann, Tammy
core  

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

Advanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang, Binxiang Zhu, Yuzhi He, Yang Tian, Honglei Kang, Shian Hu, Pengju Wang, Yong Xu, Zhuowei Lei, Peijun Qi, Hao Yang, Yang Lin, Yimin Dong, Feng Li, Hanfeng Guan   +14 more
wiley   +1 more source

A Biocompatible Microdroplet Platform Incorporating MSC-Derived Exosomes for Bone Regeneration and Osteoporosis Treatment

International Journal of Nanomedicine
Jincheng Sima,1,* Junrong Chen,1,* Xiliang Liu,2 Dinghong Li,1 Wenqing Huang,1 Yi Wang,1 Yaping Ma,1 Yi Zhang,1,2 Xin Wang1,3,41Department of Orthopaedic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, People’s ...
Sima J, Chen J, Liu X, Li D, Huang W, Wang Y, Ma Y, Zhang Y, Wang X   +8 more
doaj  

Current Diagnosis and Treatment in Orthopedics

, 2000
iii.758 hal.;ill.; 24 ...
Current
core  

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

Advanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai, Tao Xu, Rui Ma, Weikun Meng, Shutao Gao, Yakefu Abulizi, Alafate Kahaer, Chuanhui Xun, Maierdan Maimaiti, Rui Cao, Weidong Liang, Polati Maimaiti, Qiang Deng, Jun Sheng, Ting Wang, Mingchong Liu, Weibin Sheng   +16 more
wiley   +1 more source

Treatment Strategies for Distal Clavicle Fractures: A Narrative Review

Orthopedic Research and Reviews
Lei Yue,* Changsheng Huang,* Jianming Zhang, Ziqi Wang, Shijun Wang, Haolin Sun Department of Orthopedics, Peking University First Hospital, Beijing, People’s Republic of China*These authors contributed equally to this ...
Yue L, Huang C, Zhang J, Wang Z, Wang S, Sun H   +5 more
doaj  

Orthopedics and COVID-19: Scientific Publications Rush

, 2020
Background The purpose of this literature review is to analyze all the articles related to COVID-19 and orthopedics and to shed light on the scientific evidence that has actually been found.
D'Ambrosi, Riccardo
core   +1 more source

Obesity in orthopedics and trauma surgery [PDF]

, 2014
In 2012, 32.3% of the French population over 18years of age was considered overweight (25 ...
Parratte, S., Pesenti, S., Argenson, J.-N.   +2 more
core   +1 more source