Results 71 to 80 of about 201,296 (289)

“Membrane‐Guided” Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons

Advanced Science, EarlyView.
This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang, Lei Ye, Peigen Xie, Tao Song, Jian Chen, Heng Zhao, Zhengshan Liu, Xi Chen, Jianing Ding, Xintian Ding, Ao Shao, Miaomiao Wu, Fengdong Zhao, Siyue Tao, Tao You   +14 more
wiley   +1 more source

Treatment Strategies for Distal Clavicle Fractures: A Narrative Review

Orthopedic Research and Reviews
Lei Yue,* Changsheng Huang,* Jianming Zhang, Ziqi Wang, Shijun Wang, Haolin Sun Department of Orthopedics, Peking University First Hospital, Beijing, People’s Republic of China*These authors contributed equally to this ...
Yue L, Huang C, Zhang J, Wang Z, Wang S, Sun H   +5 more
doaj  

Patient education on oncology orthopedics [PDF]

, 2014
Author: Renata Grymová Institution: Institute of social medicine Faculty of medicine in Hradec Kralove Nursing care department Name of theses: Patient education on oncology orthopedics Head of theses: Mgr.
Grymová, Renata
core  

CNN Attention Guidance for Improved Orthopedics Radiographic Fracture Classification

, 2022
CNN Attention Guidance for Improved Orthopedics Radiographic Fracture ...
JW Verjans (18116032), MF Van Boxel (20665310), JN Doornberg (14462433), RL Jaarsma (14462424), H Shen (7708979), Z Liao (13298031), A Van Den Hengel (13507045), K Liao (9886067), J Prijs (20665313)   +8 more
core  

A Bone Marrow–Mimetic Hydrogel Enables Dual‐Phase Hemostasis and Vascularized Osteogenesis for Cranial Defects

Advanced Science, EarlyView.
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che, Donghong Li, Huan Zhang, Tingting Xu, Juhan Li, Xuanzhou Chen, Louis D. Zhang, Shuguang Wang, Dianwen Song, Dongyong Sha   +9 more
wiley   +1 more source

Burden of Malignant Neoplasm of Bone and Articular Cartilage: Trends (1990–2021), Projections to 2030, and Comparison Between China and the G20 Countries (GBD 2021)

Clinical Epidemiology
Zhongjiang Lan,1,2,* Le Zhou,3,4,* Yanliang Jiao,1,2 Shihu Kan,1,2 Songxiahe Zhao,1,2 Lei Chen,1,2 Yibin Du1 1Department of Orthopedics, The Third Affiliated Hospital of Anhui Medical University (The First People’s Hospital of Hefei ...
Lan Z, Zhou L, Jiao Y, Kan S, Zhao S, Chen L, Du Y   +6 more
doaj  

USE OF LASER IN MEDICINE, POTENTIAL OF USING LASER ERADIATION IN TRAUMATOLOGY AND ORTHOPEDICS

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
The aim of the present article is to analyze foreign and native literature sources devoted to the effect of laser eradiation on biological tissue. The paper describes the potential of using laser in traumatology and orthopedics, which can optimize and ...
Khotim O. A., Anosov V. S., Sychevskiy L. Z.   +2 more
doaj   +1 more source

Clinical Institute: Orthopedics & Sports Medicine

, 2018
Orthopedics and Sports Medicine Clinical Institutehttps://digitalcommons.providence.org/homepage-slideshow/1004/thumbnail ...

core  

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source