Results 111 to 120 of about 74,100 (214)

Elevated Nocturnal CO2 and Autonomic Dysfunction in Children With Down Syndrome

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Sleep‐disordered breathing (SDB) frequently complicates Down syndrome (DS). Beyond upper airway obstruction, emerging evidence suggests an autonomic nervous system (ANS) dysfunction affecting CO2 regulation. The aim of this study was to investigate nocturnal gas exchanges in children with DS and compare them to what has been ...
Jessica Taytard, Segolène Falquero, Sophie Denamur, Pierre‐Yves Boelle, Karl Leroux, Harriet Corvol, Aimé Ravel, Clotilde Mircher, Jeanne Toulas, Emmanuelle Prioux, Marie‐Anne Caillaud, Guillaume Aubertin, Hervé Walti   +12 more
wiley   +1 more source

Identification and Treatment of Anorexia Nervosa in Women With Perimenopause

Journal of Midwifery &Women's Health, EarlyView.
Abstract Disordered eating is a common problem that midwives will encounter as frontline primary care providers. Anorexia nervosa (AN) is a form of disordered eating that results in chronic starvation state, creating significant risk of morbidity and mortality to the patient. AN is traditionally considered a disorder of adolescence and young adulthood;
Janell Senda, Sarah Carpenter, Mary Carter‐Orbke   +2 more
wiley   +1 more source

Cancer co‐medication quality in older patients with polypharmacy: A large randomized trial testing a medication review versus usual care

Journal of Internal Medicine, EarlyView.
Abstract Background Evidence from randomized controlled trials (RCTs) testing medication reviews in geriatric oncology is sparse. Methods We conducted a single‐blinded RCT in ten rehabilitation clinics across Germany. Patients with common cancers, aged ≥ 65 years, and polypharmacy (regularly ≥ five drugs) were randomly allocated in equal proportions to
Miriam Degen, Annette Kopp‐Schneider, Tomislav Vlaski, Sigrid Carlsson, Peter Hallermann, Ludmilla Jewlanowa, Jana Barinoff, Valentin Goede, Christian Lüders, Thomas Kiefer‐Trendelenburg, Diana Lüftner, Jasmin Doll, Jürgen Wagner, Birgit Leibbrand, Hermann Brenner, Ben Schöttker   +15 more
wiley   +1 more source

Trait Neuroticism and the Nocebo Effect: The Mediating Role of Side‐Effect Expectations

Journal of Personality, EarlyView.
ABSTRACT Objective Neuroticism has not only been linked to heightened negative expectations and general somatic complaints but also to increased nocebo responses following medical treatments. Since side‐effect expectations are considered a main driver of nocebo responses, we tested whether side‐effect expectations mediate the neuroticism–nocebo ...
Anton Fischer, Li‐Ching Chuang, Nick Augustat, Pia von Blanckenburg, Erik M. Mueller   +4 more
wiley   +1 more source

Drug Therapy for Managing Primary Orthostatic Hypotension

, 2017
Primary orthostatic hypotension is a condition that is overlooked and undertreated. It is clinically defined as a decrease of 20 mm Hg in systolic or 10 mm Hg in diastolic BP within 3 minutes of standing. Primary orthostatic hypotension (OH) symptoms are
Hale, Genevieve M
core   +1 more source

Midodrine as a Countermeasure for Post-Spaceflight Orthostatic Hypotension [PDF]

, 2008
One possible mechanism for post-spaceflight orthostatic hypotension, which affects approximately 30% of astronauts after short duration shuttle missions, is inadequate norepinephrine release during upright posture.
Stenger, Michael B., Stein, Sydney P., Meck, Janice V., Platts, Steven H.   +3 more
core  

Physiological and Cardiac Effects of Weight Loss in Adolescents With Atypical Anorexia Nervosa Versus Those Undergoing Bariatric Surgery: A Retrospective Comparative Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objective Adolescents with atypical anorexia nervosa (AAN) experience cardiac complications at rates comparable to typical anorexia nervosa, despite remaining within or above a normal weight range. The physiological mechanisms underlying this paradox remain poorly understood.
Tomer Mevorach, Amit Goldstein, Orly Lavan, Shelly Shteinling, Adi Sela, Silvana Fennig   +5 more
wiley   +1 more source

Tilt Table Testing in Paediatric Orthostatic Intolerance: Is 10 Min Long Enough?

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim Recent cardiovascular literature suggests that orthostatic testing protocols should be tailored according to diagnostic purpose, distinguishing syncope evaluation from assessment of autonomic dysfunction in chronic orthostatic intolerance (COI).
Wonshik Choi, Sin Weon Yun
wiley   +1 more source

Validation of a questionnaire for orthostatic hypotension for routine clinical use

Aim: To validate a new patient-reported outcome measure for routine clinical use.Methods: A total of 50 older individuals with orthostatic hypotension who attended a falls and syncope clinic completed three questionnaires, the recently developed ...
Frith J, Newton JL
core   +4 more sources

Reflex Syncope With Complete Heart Block Triggered by Swallowing in a Patient on Immune Checkpoint Inhibitor Therapy

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) are now standard of care for most advanced solid tumors. While effective, they are associated with immune‐related adverse events (irAEs), including rare autonomic complications. We present a patient with metastatic lung adenocarcinoma receiving nivolumab and ipilimumab who developed reflex syncope with ...
Ashley Bouzon, Michael Oropesa, Bardia Adibmoradi, Daniel Weitz   +3 more
wiley   +1 more source