ABSTRACT Trazodone is an antidepressant approved for the treatment of major depressive disorder and is associated with a low incidence of sexual dysfunction. However, its effects on male reproductive health are not yet fully understood. Therefore, this study aimed to evaluate the effects of repeated trazodone administration on reproductive parameters ...
Maria Santana da Silva +13 more
wiley +1 more source
Severe orthostatic hypotension after left atrial appendage occlusion. [PDF]
Kopreski C +3 more
europepmc +1 more source
INtraVESical immunoTherapy (INVEST) prior to radical cystectomy for bladder cancer: trial protocol
Background High‐risk non‐muscle‐invasive bladder cancer (HRNMIBC) has a variable prognosis, managed predominantly by local surgical resection and intravesical Bacillus Calmette–Guérin (BCG), or radical cystectomy (RC). Current treatments are poorly tolerated, have supply limitations and often fail to control the disease.
Ruby Lister‐Whelan +13 more
wiley +1 more source
Factors associated with orthostatic hypotension presence and severity in multiple system atrophy: a cross-sectional study. [PDF]
Zhang K +8 more
europepmc +1 more source
ABSTRACT Aim To quantify the association between cardiovascular autonomic neuropathy (CAN) and heart failure (HF) in individuals with type 2 diabetes (T2D). Materials and Methods Two hundred T2D individuals were recruited from two Danish outpatient clinics between 2021–2024. CAN was defined by abnormal cardiovascular autonomic reflex test results.
Jonas R. Schaarup +7 more
wiley +1 more source
Drug-Induced Orthostatic Hypotension in UK Primary Care: A Self-Controlled Case Series Study. [PDF]
Bhanu C +5 more
europepmc +1 more source
Neural Correlates of Apathy in Multiple System Atrophy: A Clinical and Perfusion Imaging Study
In 76 patients with multiple system atrophy (MSA) and relatively preserved global cognition, apathy was present in 55.3%, with no association with motor severity or depressive symptoms. Reduced medial prefrontal cortex (mPFC) perfusion was independently associated with apathy after adjustment for clinical variables, while exploratory covariance ...
Yuki Nakagawa +9 more
wiley +1 more source
A Review of Clinical Trial and Meta-Analyses of BP Treatment Strategies for Patients with Orthostatic Hypotension: Blood Pressure Management in Patients with Hypertension and Orthostatic Hypotension. [PDF]
Rajesh S +4 more
europepmc +1 more source
Study population, methodology and key findings of the study. ABSTRACT Aims This study aimed to evaluate the clinical efficacy of SD‐ΔRR as a novel methodology for short‐duration heart rate variability (HRV) assessment for the diagnosis of diabetic sensorimotor polyneuropathy (DSPN) in patients with diabetes.
Katsuyoshi Katayama +13 more
wiley +1 more source
Orthostatic hypotension as a marker of increased arterial stiffness in diabetes mellitus. [PDF]
Oruc M, Helvacı O, Oruc A, Derici U.
europepmc +1 more source

