Results 61 to 70 of about 160,818 (303)

A new staging system for hereditary transthyretin amyloidosis in the era of specific amyloidosis therapies

open access: yesESC Heart Failure, EarlyView.
The aim of our study was to develop a more accurate staging system for hereditary ATTR patients currently receiving specific treatment. A staging system was created using as criteria: GLS ≤ −11%, NT‐proBNP ≤ 2,000 ng/L, and eGFR ≤ 65 mL/min. We managed to accurately stratify patients into three disease stages, significantly different in terms of ...
Gabriela Neculae   +7 more
wiley   +1 more source

Global patterns of polypharmacy after acute heart failure hospitalization: Prevalence and outcomes from the REPORT‐HF registry

open access: yesEuropean Journal of Heart Failure, EarlyView.
Global patterns of polypharmacy after acute heart failure hospitalization. GDMT, guideline‐directed medical therapy; HF, heart failure. Aims Polypharmacy, defined as the concurrent use of ≥5 medications, is prevalent among older adults with heart failure (HF).
Wan Ting Tay   +19 more
wiley   +1 more source

Progress of non‐motor symptoms in early‐onset Parkinson's disease

open access: yesIbrain, EarlyView.
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang   +5 more
wiley   +1 more source

Cardiorespiratory Response to Exercise in Parkinson's Disease: Associations with Autonomic Dysfunction and Physical Activity

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Both autonomic dysfunction and low levels of physical activity could contribute to reduced cardiorespiratory fitness in people with Parkinson's disease (PD). However, the interrelationship between these concepts is not well understood.
Kars I. Veldkamp   +5 more
wiley   +1 more source

Subcutaneous Apomorphine Infusion Initiation Is Associated with Impulse Control Disorder Attenuation in Advanced Parkinson's Disease Patients: Insights from the French NS‐Park Cohort

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Impulse control disorders (ICD) are common non‐motor complications in Parkinson's disease (PD), particularly in patients receiving oral dopamine agonists (DA). Continuous subcutaneous apomorphine infusion (CSAI) is a device‐aided therapy for advanced PD, but its effects on ICD remain underexplored in real‐world settings.
Clément Desjardins   +249 more
wiley   +1 more source

A Systematic Review of the Parkinson's Foundation Hospital Care Recommendations

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background People with Parkinson's disease (PwP) face increased risks of complications and longer hospital stays compared to the general population. Four major factors contribute to increased morbidity and mortality during hospitalization: medication timing errors, administration of harmful medications, restricted mobility, and dysphagia ...
Ariane Veilleux Carpentier   +12 more
wiley   +1 more source

Orthostatic Hypotension

open access: yesJournal of the American College of Cardiology, 2015
Orthostatic hypotension (OH) is a common cardiovascular disorder, with or without signs of underlying neurodegenerative disease. OH is diagnosed on the basis of an orthostatic challenge and implies a persistent systolic/diastolic blood pressure decrease of at least 20/10 mm Hg upon standing.
Ricci, F.   +2 more
openaire   +6 more sources

Orthostatic-induced Hypotension Attenuates Cold Pressor Pain Perception

open access: yes, 2010
In recent years, numerous studies have established a connection between blood pressure and nocioception. While this connection is well documented in the literature, its underlying physiological mechanisms have yet to be elucidated.
Drury, Daniel G., Wonders, Karen Y.
core  

The Management of Parkinson's Disease Before, during and after Pregnancy—an MDS Scientific Issues Committee Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Pregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence‐based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early‐onset Parkinson's disease (PD).
Alexander C. Lehn   +18 more
wiley   +1 more source

Association of orthostatic hypotension with incident dementia, stroke, and cognitive decline

open access: yesNeurology, 2018
Objective To examine associations of orthostatic hypotension (OH) with dementia and long-term cognitive decline and to update previously published results in the same cohort for stroke with an additional 16 years of follow-up.
Andreea M. Rawlings   +10 more
semanticscholar   +1 more source

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