Results 81 to 90 of about 158,043 (302)

Squatting, a posture test for studying cardiovascular autonomic neuropathy in diabetes. [PDF]

open access: yes, 2011
Cardiovascular autonomic neuropathy (CAN) is a frequent complication of diabetes mellitus, which is associated with increased morbidity and mortality. It involves both the parasympathetic and sympathetic nervous systems, and may be diagnosed by classical
A.J. Scheen   +42 more
core   +1 more source

Vestibular Dysfunction in Parkinson's Disease: A Systematic Review of Signs and Symptoms

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Despite the growing interest in the link between Parkinson's disease (PD) neuropathology and vestibular system, there is still a lack of consensus about the presence of vestibular dysfunctions in PD. Objective This review aims to identify vestibular signs and symptoms reported in PD patients and to summarize and critically appraise ...
Francisco Rosado‐Martins   +5 more
wiley   +1 more source

A Young Female Who Develops Tachycardia and Orthostatic Intolerance Following a Recent Infection [PDF]

open access: yes, 2013
Case Presentation The patient is a 20-year-old female with a history of asthma and anxiety with panic attacks who presented with palpitations and lightheadedness/pre-syncope. The morning of admission, she was attending a seminar and experienced an acute
Valentino, MD, PhD, Michael A.
core   +2 more sources

Orthostatic hypotension and symptomatic subclinical orthostatic hypotension increase risk of cognitive impairment: an integrated evidence review and analysis of a large older adult hypertensive cohort

open access: yesEuropean Heart Journal, 2018
Aims Systematically reviewing the literature found orthostatic hypotension (OH) to be associated with an increased risk of incident dementia but limited data were available in those at highest risk, the hypertensive oldest-old. Our aim was to analyse the
R. Peters   +8 more
semanticscholar   +1 more source

Autonomic symptoms in hypertensive patients with post-acute minor ischemic stroke [PDF]

open access: yes, 2015
Background Most studies regarding autonomic dysfunction in ischemic stroke are limited to heart rate and blood pressure changes during the acute phase. However, there are few data on quantitative assessment of autonomic symptoms.
Adams   +34 more
core   +1 more source

Orthostatic Hypotension and Risk of Clinical and Subclinical Cardiovascular Disease in Middle‐Aged Adults

open access: yesJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018
Background Although orthostatic hypotension (OH) is a well‐recognized manifestation of neuropathy and hypovolemia, its contribution to cardiovascular disease (CVD) risk is controversial.
S. Juraschek   +7 more
semanticscholar   +1 more source

Demographic and Clinical Profiles of Parkinson's Disease in India: Observations from a Nation‐Wide Multicenter Study

open access: yesMovement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) phenotype may vary with genetic, ethno‐geographic, cultural, and environmental factors. Objectives The aim was to develop a clinical database of PD in India and assess the influence of age‐at‐onset (AAO), gender, and motor subtype on the clinical profile of PD.
Asha Kishore   +27 more
wiley   +1 more source

The efficacy of nonpharmacologic intervention for orthostatic hypotension associated with aging

open access: yesNeurology, 2018
Objective To determine the efficacy and safety of nonpharmacologic interventions for orthostatic hypotension (OH) secondary to aging. Methods A total of 150 orthostatic challenges were performed in 25 older people (age 60–92 years) to determine ...
J. Newton, J. Frith
semanticscholar   +1 more source

Structure‐Guided Identification and Evaluation of Epalrestat and Ranirestat‐Like Compounds Against Aldose Reductase: Therapeutic Management of Diabetic Neuropathy

open access: yesChemistryOpen, EarlyView.
Structure‐based virtual screening of PubChem compounds identifies two novel epalrestat and ranirestat‐like inhibitors with improved affinity and pharmacokinetic profiles targeting aldose reductase. Molecular docking, ADMET filtering, and 500‐ns molecular dynamics simulations confirm the stability and interaction specificity of the candidates ...
Mohd Shahnawaz Khan   +3 more
wiley   +1 more source

Prohormones in the early diagnosis of cardiac syncope [PDF]

open access: yes, 2017
Background--The early detection of cardiac syncope is challenging. We aimed to evaluate the diagnostic value of 4 novel prohormones, quantifying different neurohumoral pathways, possibly involved in the pathophysiological features of cardiac syncope ...
Badertscher, Patrick   +36 more
core   +1 more source

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