Results 91 to 100 of about 123,113 (271)

Human hypoxia models in aerospace medicine: Potential applications for human pharmacological research

British Journal of Clinical Pharmacology, EarlyView.
Aerospace medicine required controlled terrestrial models to investigate influences of altered atmosphere conditions, such as hypoxia, on human health and performance. These models could potentially be expanded to encompass disease conditions or treatment targets regulated through hypoxia or hypercapnia.
Titiaan E. Post, Cayla Denney, Adam Cohen, Jens Jordan, Ulrich Limper   +4 more
wiley   +1 more source

Postural tachycardia during head-up tilt test predicts persistent orthostatic intolerance in young adults

Zdravniški Vestnik, 2013
Background: Head-up tilt (HUT) test is an important tool in establishing the cause of past syncope. As postural tachycardia is associated with orthostatic intolerance, we hypothesise that heart rate (HR) increase during the early phase of HUT can be used
Mojca Kirbiš, Fajko F. Bajrović, Mojca Čižek Sajko, Bernard Meglič, Anton Grad   +4 more
doaj  

DI-5-CUFFS: Venoconstrictive Thigh Cuffs Limit Body Fluid Changes but Not Orthostatic Intolerance Induced by a 5-Day Dry Immersion

Frontiers in Physiology, 2020
Venoconstrictive thigh cuffs are used by cosmonauts to ameliorate symptoms associated with cephalad fluid shift. A ground simulation of microgravity, using the dry immersion (DI) model, was performed to assess the effects of thigh cuffs on body fluid ...
Adrien Robin, Aline Auvinet, B. Degryse, Ronan P. Murphy, M. Bareille, Arnaud Beck, C. Gharib, G. Gauquelin‐Koch, Aude Daviet, Françoise Larcher, M. Custaud, N. Navasiolava   +11 more
semanticscholar   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Central nervous system involvement in cardiac amyloidosis: Redefining the heart‐brain axis

European Journal of Clinical Investigation, EarlyView.
Central nervous system involvement in cardiac amyloidosis. Amyloidosis is a systemic disease that can directly affect the central nervous system. Furthermore, the amyloid cardiomyopathy can indirectly affect the central nervous system by inducing systemic hypoperfusion and increasing the risk of acute ischaemic stroke.
Domenico Mario Giamundo, Giuliano Cassataro, Stefano Ministrini, Simon F. Stämpfli   +3 more
wiley   +1 more source

A numerical model to assess deconditioning of the cardiovascular system in long-term exposure to microgravity. Verification and simulation of Mars mission scenarios [PDF]

, 2016
Numerical simulations of the cardiovascular system are particularly important in scenarios where it is difficult to experiment different weightlessness exposure conditions.
Pérez Poch, Antoni
core  

Effect of Ceiling Fans on Core Temperature in Bed‐Resting Older Adults Exposed to Indoor Overheating

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Rising global temperatures have increased indoor overheating risks, posing significant health threats to vulnerable populations, particularly older adults. While electric fans are recommended for cooling at temperatures up to 40°C, the efficacy of ceiling fans in very warm indoor temperatures (~31°C) remains understudied.
Fergus K. O'Connor, Robert D. Meade, Kristina‐Marie T. Janetos, Caroline Li‐Maloney, Ronald J. Sigal, Pierre Boulay, Glen P. Kenny   +6 more
wiley   +1 more source

Diabetic gastroenteropathy: Associations between gastrointestinal symptoms, motility, and extraintestinal autonomic measures

Neurogastroenterology &Motility, EarlyView.
We found no associations between gastrointestinal and extraintestinal measures of diabetic autonomic neuropathy. Nonetheless, gastrointestinal symptoms increased with the severity of cardiovascular autonomic neuropathy and were associated with gastrointestinal measures.
Ditte S. Kornum, Christina Brock, Tina Okdahl, Davide Bertoli, Huda Kufaishi, Anne‐Marie Wegeberg, Katrine L. Høyer, Esben B. Mark, Birgitte Brock, Christian S. Hansen, Filip K. Knop, Asbjørn M. Drewes, Klaus Krogh   +12 more
wiley   +1 more source

Prolonged Gastrointestinal Transit Times and Dysmotility in m.3243A>G Mitochondrial Disease

Neurogastroenterology &Motility, EarlyView.
Carriers of m.3243A>G mitochondrial disease have impaired mitochondrial adenosine triphosphate (ATP) production. Our findings indicate that patients exhibit gastrointestinal dysmotility as assessed by the wireless motility capsule SmartPill. This indicates a critical role of mitochondrial ATP in normal gastrointestinal function.
Simone Rask Nielsen, Malene Pontoppidan Stoico, Donghua Liao, Asbjørn Mohr Drewes, Inge Søkilde Pedersen, Anja Lisbeth Frederiksen, Christina Brock   +6 more
wiley   +1 more source

Neurohumoral mechanisms associated with orthostasis: Reaffirmation of the significant contribution of the heart rate response

Frontiers in Physiology, 2014
The inability to compensate for acute central hypovolemia underlies the clinical development of orthostatic hypotension and instability (e.g., syncope). Although neuro-humoral control of both cardiac output and peripheral vascular resistance contributes ...
Victor A Convertino
doaj   +1 more source