Results 91 to 100 of about 84,351 (216)

Orthostatic intolerance and motion sickness after parabolic flight

, 2001
Because it is not clear that the induction of orthostatic intolerance in returning astronauts always requires prolonged exposure to microgravity, we investigated orthostatic tolerance and autonomic cardiovascular function in 16 healthy subjects before ...
Roberta L. Bondar, Peyman Moradshahi, Janice M. Fritsch-Yelle, Phillip A. Low, Scott J. Wood, Flo Stein, Todd T. Schlegel, Troy E. Brown, Edgar W. Benavides, Deborah L. Harm   +9 more
core   +1 more source

Mechanism‐Informed Pharmacotherapy Optimization and Deprescribing: A Redox–Mitochondrial Framework

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
From cumulative drug burden to mitochondrial stress and functional decline. The graphical abstract summarizes the central concept of the review, illustrating how cumulative pharmacotherapy exposure may contribute to redox–mitochondrial stress and thereby reduce biological and functional resilience.
Boštjan Martinc
wiley   +1 more source

Postural tachycardia syndrome and other forms of orthostatic intolerance in Ehlers-Danlos syndrome

, 2018
Objective: To review the association between orthostatic intolerance syndromes and both joint hypermobility and Ehlers-Danlos syndrome, and to propose reasons for identifying hereditary connective tissue disorders in those with orthostatic intolerance in
Peter C. Rowe, De Wandele, Inge, Maria Roma, Marden, Colleen L, Francomano, Clair A, Inge De Wandele, Roma, Maria, Clair A. Francomano, Rowe, Peter C, Colleen L. Marden   +9 more
core   +1 more source

Exercise and Autonomic Cardiovascular Function—Insights From Spinal Cord‐Injured Humans: A Narrative Review

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT The cardiovascular response to acute exercise is mediated by the autonomic nervous system (ANS) control mechanisms that modulate vascular resistance to support blood pressure and ensure adequate blood flow to active muscles. These autonomic neurocirculatory control mechanisms include a feedforward mechanism, known as central command, and three
Rasmus Kopp Hansen, Ryan Godsk Larsen, Tom E. Nightingale, Daniel D. Hodgkiss, Niels H. Secher, Stefanos Volianitis   +5 more
wiley   +1 more source

Heart rate variability analysis in postural orthostatic tachycardia syndrome: a case report

Heart International, 2006
The authors present a case of 36 year old male patient with idiopathic postural orthostatic tachycardia syndrome (POTS) diagnosed during head-up tilt testing.
Raffaele Calabrò, Lucio Santangelo, Cristina Savarese, Carolina Pagano, Ernesto Ammendola, Ilaria De Crescenzo, Vincenzo Russo   +6 more
doaj   +1 more source

Infusion rate adjustment in enzyme replacement therapy with pabinafusp alfa for mucopolysaccharidosis II

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3140-3150, September 2026.
Abstract Aims Enzyme replacement therapy (ERT) for mucopolysaccharidosis II (MPS II) requires long‐term, weekly intravenous infusions often lasting over 3 h each time, which can burden paediatric patients and caregivers and negatively affect their quality of life and treatment compliance.
Kimitoshi Nakamura, Norio Sakai, Hideaki Hirai, Naoko Takasao, Ryo Ibaraki, Tatsuyoshi Yamamoto, Yuji Sato   +6 more
wiley   +1 more source

Time-Frequency Analysis of Cardiovascular and Cardiorespiratory Interactions During Orthostatic Stress by Extended Partial Directed Coherence

Entropy, 2019
In this study, the linear method of extended partial directed coherence (ePDC) was applied to establish the temporal dynamic behavior of cardiovascular and cardiorespiratory interactions during orthostatic stress at a 70° head-up tilt (HUT) test on ...
Sonia Charleston-Villalobos, Sina Reulecke, Andreas Voss, Mahmood R. Azimi-Sadjadi, Ramón González-Camarena, Mercedes J. Gaitán-González, Jesús A. González-Hermosillo, Guadalupe Hernández-Pacheco, Steffen Schulz, Tomás Aljama-Corrales   +9 more
doaj   +1 more source

Orthostatic intolerance and the cardiovascular response to early postoperative mobilization

, 2009
Udgivelsesdato: 2009-JunBACKGROUND: A key element in enhanced postoperative recovery is early mobilization which, however, may be hindered by orthostatic intolerance, that is, an inability to sit or stand because of symptoms of cerebral hypoperfusion as ...
Bundgaard-Nielsen, M, Secher, N H, Jørgensen, Christoffer Calov, Jørgensen, T B, Kehlet, H, Ruhnau, B   +5 more
core   +1 more source

Tirzepatide and SGLT2 Inhibitors for Heart Failure With Preserved Ejection Fraction and Obesity: Entering a New Cardiometabolic Therapeutic Era

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Tirzepatide and SGLT2 inhibitors act through distinct but complementary mechanisms in obesity‐related HFpEF: tirzepatide targets adiposity, inflammation, and insulin resistance, while SGLT2 inhibitors improve decongestion, myocardial energetics, and cardiac remodeling.
Zakariye Isak Mohamed, Abdinasir Adam Shidane, Abdullahi Mohamud Abdiasis, Mohamed Hassan Hussein, Ayaanle Osman Ibrahim, Anas Ali Abdi, Kowthar Ismail Hashi, Mohamed Abdullahi Mohamud, Ali Jimale Mohamed   +8 more
wiley   +1 more source

Clinical profile and cardiovascular autonomic function tests in patients with postural orthostatic tachycardia syndrome

CHRISMED Journal of Health and Research, 2019
Background: Postural orthostatic tachycardia syndrome (POTS) is an autonomic disorder characterized by the clinical symptoms of orthostatic intolerance such as light-headedness, fatigue, sweating, tremor, anxiety, palpitation, exercise intolerance, and ...
Neeraj, Suchitra Deolalikar, Aman Pannu, Jeyaraj Durai Pandian   +3 more
doaj   +1 more source