Results 121 to 130 of about 84,351 (216)

Orthostatic intolerance and the postural tachycardia syndrome : genetic and environment pathophysiologies. Neurolab Autonomic Team

, 2000
Orthostatic intolerance is a common problem for inbound space travelers. There is usually tachycardia on standing but blood pressure may be normal, low or, rarely, elevated.
J. R. Shannon, Diedrich, A., D. Robertson, R. Carson, I. Biaggioni, G. Jacob, Carson, R., A. Diedrich, Furlan, R., Robertson, D., Shannon, J.R., Biaggioni, I., Ertl, A.C., R. Furlan, Jordan, J., A. C. Ertl, Jacob, G., J. Jordan   +17 more
core   +1 more source

Blood flow restriction: The acute effects of body tilting and reduced gravity analogues on limb occlusion pressure

Experimental Physiology, Volume 111, Issue 9, Page 4103-4114, 1 September 2026.
Abstract Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP.
Patrick Swain, Nick Caplan, Luke Hughes
wiley   +1 more source

Isometric training at longer muscle–tendon complex lengths: A potential countermeasure to impaired neuro‐muscle–tendon function during space travel

Experimental Physiology, Volume 111, Issue 9, Page 4041-4053, 1 September 2026.
Abstract Manned space exploration to distant destinations, including Mars, continues to be an aspiration of humankind. Space travel does, however, present many challenges to the body, amongst which adaptation to microgravity is perhaps the largest. For instance, both short and long manned spaceflight missions have shown substantial deleterious effects ...
Gerard McMahon, Andy Sanderson, Hans Degens   +2 more
wiley   +1 more source

Cerebrovascular pulsatility following long duration spaceflight is associated with changes in pulse pressure and carotid artery stiffness

Experimental Physiology, Volume 111, Issue 9, Page 4235-4247, 1 September 2026.
Abstract Central artery stiffening increases the haemodynamic pulsations transmitted downstream towards target organs, including the brain. While recent evidence suggests that long duration spaceflight is associated with reduced common carotid artery (CCA) distensibility, cerebrovascular pulsatility has not been extensively characterized in astronauts.
Roxanne Fournier, Danielle K. Greaves, J. Kevin Shoemaker, Philippe Arbeille, Richard L. Hughson, Andrew D. Robertson   +5 more
wiley   +1 more source

Orthostatic Intolerance and Motion Sickness After Parabolic Flight

, 1999
Orthostatic intolerance is common in astronauts after prolonged space flight. However, the "push-pull effect" in military aviators suggests that brief exposures to transitions between hypo- and hypergravity are sufficient to induce untoward autonomic ...
Schlegel, Todd T., Bondar, Roberta L., Harm, Deborah L., Wood, Scott J., Moradshahi, Peyman, Low, Phillip A., Stein, Flo, Brown, Troy E., Benavides, Edgar W.   +8 more
core  

Is fatigue in Marfan syndrome related to orthostatic intolerance?

, 2008
Patients with Marfan syndrome have a tall stature, which could be associated with low orthostatic tolerance. Fatigue, a common complaint of these patients, is also related to orthostatic intolerance.
Mulder, Barbara J. M., Wieling, Wouter, van Montfrans, Gert A., van Dijk, Nynke, Boer, Mardi C.   +4 more
core   +1 more source

Midodrine prevents orthostatic intolerance associated with simulated spaceflight

, 2001
Many astronauts after being weightless in space become hypotensive and presyncopal when they assume an upright position. This phenomenon, known as orthostatic intolerance, may interfere with astronaut function during reentry and after spaceflight and ...
Richard J. Cohen, Derin Sherman, Daniel Bloomfield, Siri Rostoft, Karin Toska, Gordon H. Williams, Craig D. Ramsdell, Thomas J. Mullen, Grete H. Sundby, Nikolai Aljuri, Janice Yelle, Natalie Sheynberg, Ming Maa, Ramakrishna Mukkamala   +13 more
core   +1 more source

Haemodynamic responses to head‐up tilt versus lower‐body negative pressure in type 1 diabetes

Experimental Physiology, Volume 111, Issue 9, Page 4089-4102, 1 September 2026.
Abstract Head‐up tilt (HUT) and lower‐body negative pressure (LBNP) both reduce central blood volume but differ in heart orientation and regional fluid shifts. Whether they evoke comparable cardiovascular regulation when matched for preload remains uncertain.
Victorien Faivre‐Rampant, Jules Warnier, Perrine Larmet, Damien Garcia, Michael Joubert, Damian Miles Bailey, Igor Mekjavic, Hervé Normand, Amir Hodzic   +8 more
wiley   +1 more source

Association of blood pressure variability with orthostatic intolerance symptoms.

, 2017
The short-term blood pressure variability (BPV) reflects autonomic regulatory mechanisms. However, the influence of BPV in orthostatic intolerance (OI) is unknown. Herein, we assessed BPV profiles in patients with OI and determined their association with
Kon Chu, Sang Kun Lee, Jun-Sang Sunwoo, Manho Kim, Jung-Ick Byun, Do-Yong Kim, Tae-Joon Kim, Tae-Won Yang, Ki-Young Jung, Soon-Tae Lee, Keun-Hwa Jung, Jung-Ah Lim, Jangsup Moon, Kyung-Il Park   +13 more
core   +1 more source

Adaptive Approaches to Exercise Rehabilitation for Postural Tachycardia Syndrome and Related Autonomic Disorders

Archives of Rehabilitation Research and Clinical Translation
Exercise is a well-documented, nonpharmacologic treatment for individuals with autonomic dysfunction and associated orthostatic intolerance, such as postural tachycardia syndrome and related disorders.
Lauren Ziaks, PT, DPT, ATC, Kathryn Johnson, PT, DPT, Kelsi Schiltz, PT, DPT, Ryan Pelo, PT, DPT, PhD, Guillaume Lamotte, MD, MSc, Claudia Dal Molin, DO, RMSK, Tae Chung, MD, Melissa M. Cortez, DO   +7 more
doaj   +1 more source