Results 31 to 40 of about 9,253 (193)

External validation of a simple clinical tool used to predict falls in people with Parkinson disease [PDF]

, 2015
Published in final edited form as: Parkinsonism Relat Disord. 2015 August ; 21(8): 960–963. doi:10.1016/j.parkreldis.2015.05.008.BACKGROUND: Assessment of fall risk in an individual with Parkinson disease (PD) is a critical yet often time consuming ...
Canning, Colleen G., Cavanaugh, James T., Dibble, Leland E., Duncan, Ryan P., Earhart, Gammon M., Ellis, Terry D., Ford, Matthew P., Foreman, K. Bo, Leddy, Abigail L., Paul, Serene S., Thackeray, Anne   +10 more
core   +1 more source

Abdominal Compartment Syndrome Secondary to Chronic Constipation

Case Reports in Pediatrics, 2011
Abdominal compartment syndrome (ACS) is defined as an elevated intraabdominal pressure with evidence of organ dysfunction. The majority of published reports of ACS are in neonates with abdominal wall defects and in adults following trauma or burns, but ...
Helene Flageole, Jodie Ouahed, J. Mark Walton, Yasmin Yousef   +3 more
doaj   +1 more source

A Double-Blind, Placebo-Controlled Trial Demonstrating the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of RTI-336

Frontiers in Pharmacology, 2018
Background: Preclinical and clinical data suggest that a compound which binds potently to and inhibits the dopamine transporter, but with a slower onset and offset rate than cocaine and with less abuse potential and psychomotor stimulant activity, could ...
F. Ivy Carroll, Thomas R. Kosten, Jeffrey J. Buda, Laurene Wang, Bradford B. Walters   +4 more
doaj   +1 more source

A pilot study exploring novel contexts for out-of-office blood pressure measurement

Frontiers in Cardiovascular Medicine
IntroductionOut-of-office blood pressure (BP) monitoring is increasingly valuable in the diagnosis and management of hypertension. With advances in wearable BP technologies, the ability to gain insight into BP outside of traditional centers of care has ...
Francis Allinson, Nolan Mejia, Lauren Ariniello, Giorgio Quer, Evan D. Muse, Evan D. Muse   +5 more
doaj   +1 more source

Efficacy, safety, and response predictors of Astragalus in patients with mild to moderate Alzheimer's disease: A study protocol of an assessor-blind, statistician-blind open-label randomized controlled trial

Contemporary Clinical Trials Communications
Background: This pragmatic clinical trial aims to determine the efficacy and safety of add-on Astragalus membranaceus (AM) for cognition and non-cognition in patients with of mild to moderate Alzheimer's disease complicated with orthostatic hypotension ...
Yingzhe Cheng, Lin Lin, Peilin Huang, Jiejun Zhang, Xiaodong Pan   +4 more
doaj   +1 more source

Fall Risk Assessment Experience

MedEdPORTAL, 2010
Falls are common in older adults and result in significant morbidity, including injury, pain, disability, and even death. Risk factors for falling have been identified, and interventions to improve these risk factors have been found to reduce fall rates ...
Sara Bradley, Reena Karani
doaj   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, In collaboration with the Consensus Expert Panel (CEP) members   +19 more
wiley   +1 more source

Early Physiologic Numerical and Waveform Characteristics of Simulated Hemorrhagic Events With Healthy Volunteers Donating Blood

Critical Care Explorations
OBJECTIVES:. Early signs of bleeding are often masked by the physiologic compensatory responses delaying its identification. We sought to describe early physiologic signatures of bleeding during the blood donation process. SETTING:.
Joo Heung Yoon, MD, Jueun Kim, MS, Theodore Lagattuta, RN, Michael R. Pinsky, MD, MCCM, Marilyn Hravnak, RN, PhD, Gilles Clermont, MD, MS   +5 more
doaj   +1 more source

The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management [PDF]

, 2006
Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia,
Raj, Satish R
core   +1 more source

Navigating adverse immunostimulation: A practical guide for clinical researchers

British Journal of Clinical Pharmacology, EarlyView.
Problem Setting As drug development moves towards more complex products, early clinical development programmes are increasingly hampered by unwanted and/or unexpected activation of the immune system (adverse immune stimulation, AIS). Solution At the Centre for Human Drug Research, we have introduced standardized procedures to make AIS manageable, while
Juliette A. van den Noort, Anouk C. Meijs, Naomi B. Klarenbeek, Matthijs Moerland   +3 more
wiley   +1 more source