Results 31 to 40 of about 80,562 (200)

Abdominal Compartment Syndrome Secondary to Chronic Constipation

Case Reports in Pediatrics, 2011
Abdominal compartment syndrome (ACS) is defined as an elevated intraabdominal pressure with evidence of organ dysfunction. The majority of published reports of ACS are in neonates with abdominal wall defects and in adults following trauma or burns, but ...
Helene Flageole, Jodie Ouahed, J. Mark Walton, Yasmin Yousef   +3 more
doaj   +1 more source

A Double-Blind, Placebo-Controlled Trial Demonstrating the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of RTI-336

Frontiers in Pharmacology, 2018
Background: Preclinical and clinical data suggest that a compound which binds potently to and inhibits the dopamine transporter, but with a slower onset and offset rate than cocaine and with less abuse potential and psychomotor stimulant activity, could ...
F. Ivy Carroll, Thomas R. Kosten, Jeffrey J. Buda, Laurene Wang, Bradford B. Walters   +4 more
doaj   +1 more source

A pilot study exploring novel contexts for out-of-office blood pressure measurement

Frontiers in Cardiovascular Medicine
IntroductionOut-of-office blood pressure (BP) monitoring is increasingly valuable in the diagnosis and management of hypertension. With advances in wearable BP technologies, the ability to gain insight into BP outside of traditional centers of care has ...
Francis Allinson, Nolan Mejia, Lauren Ariniello, Giorgio Quer, Evan D. Muse, Evan D. Muse   +5 more
doaj   +1 more source

Comprehensive telemedicine solution for remote monitoring of Parkinson’s disease patients with orthostatic hypotension during COVID-19 pandemic

Neurological Sciences, 2022
Orthostatic hypotension (OH) represents a frequent but under-recognized phenomenon in Parkinson’s disease (PD). During COVID-19 pandemic, Information and Communication Technologies (ICT) have become pivotal in the management of chronic diseases like PD ...
P. Polverino, M. Ajčević, M. Catalan, Claudio Bertolotti, G. Furlanis, Alessandro Marsich, A. Buoite Stella, A. Accardo, P. Manganotti   +8 more
semanticscholar   +1 more source

Comment on: Comparison of supine and seated orthostatic hypotension assessments and their association with falls and orthostatic symptoms

Journal of The American Geriatrics Society, 2022
To the Editor: Orthostatic hypotension (OH) develops in several conditions and with healthy aging. OH is defined as a drop in systolic blood pressure (BP) ≥20 mmHg, or diastolic drop of ≥10 mmHg within 3 min of standing or head-up tilt from a supine ...
J. Baker, S. Raj
semanticscholar   +1 more source

Efficacy, safety, and response predictors of Astragalus in patients with mild to moderate Alzheimer's disease: A study protocol of an assessor-blind, statistician-blind open-label randomized controlled trial

Contemporary Clinical Trials Communications
Background: This pragmatic clinical trial aims to determine the efficacy and safety of add-on Astragalus membranaceus (AM) for cognition and non-cognition in patients with of mild to moderate Alzheimer's disease complicated with orthostatic hypotension ...
Yingzhe Cheng, Lin Lin, Peilin Huang, Jiejun Zhang, Xiaodong Pan   +4 more
doaj   +1 more source

Fall Risk Assessment Experience

MedEdPORTAL, 2010
Falls are common in older adults and result in significant morbidity, including injury, pain, disability, and even death. Risk factors for falling have been identified, and interventions to improve these risk factors have been found to reduce fall rates ...
Sara Bradley, Reena Karani
doaj   +1 more source

Orthostatic Hypotension and Antiparkinsonian Drugs: A Systematic Review and Meta-analysis

Journal of Geriatric Psychiatry and Neurology, 2021
Background Orthostatic hypotension (OH) is multifactorial in Parkinson’s disease (PD). Antiparkinsonian medication can contribute to OH, leading to increased risk of falls, weakness and fatigue.
Danielle Nimmons, C. Bhanu, M. Orlu, A. Schrag, K. Walters   +4 more
semanticscholar   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Early Physiologic Numerical and Waveform Characteristics of Simulated Hemorrhagic Events With Healthy Volunteers Donating Blood

Critical Care Explorations
OBJECTIVES:. Early signs of bleeding are often masked by the physiologic compensatory responses delaying its identification. We sought to describe early physiologic signatures of bleeding during the blood donation process. SETTING:.
Joo Heung Yoon, MD, Jueun Kim, MS, Theodore Lagattuta, RN, Michael R. Pinsky, MD, MCCM, Marilyn Hravnak, RN, PhD, Gilles Clermont, MD, MS   +5 more
doaj   +1 more source