Results 41 to 50 of about 53,317 (192)

NLX‐112 Randomized Phase 2A Trial: Safety, Tolerability, Anti‐Dyskinetic, and Anti‐Parkinsonian Efficacy

open access: yesMovement Disorders, EarlyView.
Abstract Background Levodopa‐induced dyskinesia (LID) in Parkinson's disease (PD) is associated with ‘false neurotransmitter’ release of dopamine from serotonin (5‐HT) neurons. NLX‐112 is a first‐in‐class, highly selective 5‐HT1A receptor agonist which counteracts LIDs in experimental PD models.
Per Svenningsson   +13 more
wiley   +1 more source

Enhancing Vital Sign Estimation Performance of FMCW MIMO Radar by Prior Human Shape Recognition [PDF]

open access: yesarXiv, 2023
Radio technology enabled contact-free human posture and vital sign estimation is promising for health monitoring. Radio systems at millimeter-wave (mmWave) frequencies advantageously bring large bandwidth, multi-antenna array and beam steering capability.
arxiv  

The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management [PDF]

open access: yes, 2006
Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia,
Raj, Satish R
core   +1 more source

Hypovolaemic shock: assessment, pathophysiology and nursing care [PDF]

open access: yes, 2017
Hypovolaemia leads to a number of key physiological responses which require systematic assessment and interpretation. This article focuses on a case study involving a patient with Parkinson’s disease who became hypovolaemic following a fall at home, to ...
McLeod, A., Moruzzi, M.
core   +1 more source

Efficacy and Safety of Once Daily Dosing vs. Approved On/Off Dosing of Edaravone Oral Suspension Up to 48 Weeks in Patients With Amyotrophic Lateral Sclerosis (Study MT‐1186‐A02)

open access: yesMuscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims An On/Off dosing regimen of intravenous (IV) edaravone and edaravone oral suspension is approved in the US for the treatment of amyotrophic lateral sclerosis (ALS). Placebo‐controlled clinical trials showed IV edaravone slows the rate of physical functional decline.
Jeffrey Rothstein   +17 more
wiley   +1 more source

Real-time Monitoring and Early Warning Analysis of Urban Railway Operation Based on Multi-parameter Vital Signs of Subway Drivers in Plateau Environment [PDF]

open access: yesarXiv, 2020
In order to ensure the personal safety of the drivers and passengers of rail transit in plateau environment, the vital signs and train conditions of the drivers and passengers are taken as the research object, and the dynamic relationship between them is studied and analyzed.
arxiv  

Efficient Deep Learning-based Estimation of the Vital Signs on Smartphones [PDF]

open access: yesarXiv, 2022
With the increasing use of smartphones in our daily lives, these devices have become capable of performing many complex tasks. Concerning the need for continuous monitoring of vital signs, especially for the elderly or those with certain types of diseases, the development of algorithms that can estimate vital signs using smartphones has attracted ...
arxiv  

Disease modifying therapy for multiple system atrophy – Parkinsonian Type [PDF]

open access: yes, 2017
BACKGROUND: Multiple System Atrophy –Parkinsonian Type (MSA-P) is a rare, rapidly progressive neurodegenerative disease without any current treatment.
Dwyer, Sean Sullivan
core  

Pi-ViMo: Physiology-inspired Robust Vital Sign Monitoring using mmWave Radars [PDF]

open access: yesarXiv, 2023
Continuous monitoring of human vital signs using non-contact mmWave radars is attractive due to their ability to penetrate garments and operate under different lighting conditions. Unfortunately, most prior research requires subjects to stay at a fixed distance from radar sensors and to remain still during monitoring.
arxiv  

Review of published research on primary dysautonomia of domestic animals

open access: yesVeterinary Record, EarlyView.
Abstract An article published in 1992 by Marion M. Pollin and I.R. Griffiths reviewed the topic of primary dysautonomias of the autonomic nervous system of unidentified origin in multiple domestic species, specifically cats, dogs and horses. Thirty‐one years later, we appear no closer to identifying the causal agents of these strikingly similar ...
Tanith Harte   +3 more
wiley   +1 more source

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