Results 61 to 70 of about 78,201 (203)

Pharmacokinetics and safety of eptinezumab in children and adolescents with migraine

Headache: The Journal of Head and Face Pain, Volume 65, Issue 9, Page 1573-1583, October 2025.
Abstract Objective The primary objective was to characterize the pharmacokinetics (PK) and safety of eptinezumab in children and adolescents with migraine. Background Migraine in children and adolescents is a prevalent and potentially debilitating disease, and few preventive therapies are approved for use in these populations. Eptinezumab, a calcitonin
Andrew D. Hershey, Johan Areberg, Line Pickering Boserup, Annika Lindsten, Monika Rosen   +4 more
wiley   +1 more source

Trust in Transition: Exploring Changing Trust in Vaccination in the Context of Long Covid in the United Kingdom

Health Expectations, Volume 28, Issue 5, October 2025.
ABSTRACT Background New drugs and vaccines usually come with the promise and hope of benefit. We explore stories about the variable and sometimes disappointing effects of Covid‐19 vaccines in the context of post‐Covid‐19 syndrome (‘long Covid’), aiming to understand how people with long Covid made sense of unexpected vaccine responses and how these ...
Anna Dowrick, Alice MacLean, Sue Ziebland, Trish Greenhalgh   +3 more
wiley   +1 more source

The MSA Atrophy Index (MSA‐AI): An Imaging Marker for Diagnosis and Clinical Progression in Multiple System Atrophy

Annals of Clinical and Translational Neurology, Volume 12, Issue 9, Page 1823-1833, September 2025.
ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo, Kilian Hett, Amy Cooper, Amy E. Brown, Jessica Iregui, Manus J. Donahue, M. Erik Landman, Italo Biaggioni, Margaret Bradbury, Cynthia Wong, David Stamler, Daniel O. Claassen   +11 more
wiley   +1 more source

Weight Loss and Illness Severity in Adolescents With Atypical Anorexia Nervosa. [PDF]

, 2019
BACKGROUND:Lower weight has historically been equated with more severe illness in anorexia nervosa (AN). Reliance on admission weight to guide clinical concern is challenged by the rise in patients with atypical anorexia nervosa (AAN) requiring ...
Accurso, Erin C, Adams, Sally H, Buckelew, Sara M, Cheng, Jing, Garber, Andrea K, Golden, Neville H, Kapphahn, Cynthia J, Kreiter, Anna, Le Grange, Daniel, Machen, Vanessa I, Moscicki, Anna-Barbara, Saffran, Kristina, Sy, Allyson F, Wilson, Leslie   +13 more
core  

Vaccines in Current Culture: The HPV Vaccine Controversy [PDF]

, 2020
The use of vaccinations has drastically decreased mortality and morbidity rates related to infectious disease and has become an intrinsic part of modern health care.
Johnston, Alyssa
core   +1 more source

Efficacy and Safety of Once Daily Dosing vs. Approved On/Off Dosing of Edaravone Oral Suspension Up to 48 Weeks in Patients With Amyotrophic Lateral Sclerosis (Study MT‐1186‐A02)

Muscle &Nerve, Volume 72, Issue 3, Page 433-442, September 2025.
ABSTRACT Introduction/Aims An On/Off dosing regimen of intravenous (IV) edaravone and edaravone oral suspension is approved in the US for the treatment of amyotrophic lateral sclerosis (ALS). Placebo‐controlled clinical trials showed IV edaravone slows the rate of physical functional decline.
Jeffrey Rothstein, Angela Genge, Shari De Silva, Lorne Zinman, Marvin Chum, Adriano Chio, Gen Sobue, Masashi Aoki, Hiide Yoshino, Manabu Doyu, Daniel Selness, Vesna Todorovic, Nissim Sasson, Manabu Hirai, Fumihiro Takahashi, Alejandro Salah, Art Wamil, Stephen Apple   +17 more
wiley   +1 more source

Assessment of Fall Risk in Community‐Dwelling Older Adults Using the Stopping Elderly Accidents, Deaths, and Injuries Algorithm

Nursing Open, Volume 12, Issue 9, September 2025.
ABSTRACT Aim To identify individuals at risk of falls and the factors contributing to their risk, we screened community‐dwelling older adults using the Centers for Disease Control and Prevention's Stopping Elderly Accidents, Deaths, and Injuries (STEADI) Assessments. Design A descriptive correlational study design.
Kyeongra Yang, Anita Van Wingerden, Marta Galagoza, Karla Soldevilla, Ethan A. Lim, Mary L. Wagner   +5 more
wiley   +1 more source

Neurocardiogenic syncope in the intercollegiate athlete : an examination of problems and solutions : an honors thesis (HONRS 499) [PDF]

, 2000
Neurocardiogenic Syncope, a condition common in young people, is becoming more recognized in the Athletic Training profession. The purpose of this discussion is to delve into this condition and provide basic knowledge to help the Athletic Trainer manage ...
Zickgraf, Sara E.
core  

Catechol-O-methyltransferase inhibition with tolcapone reduces the "wearing off" phenomenon and levodopa requirements in fluctuating parkinsonian patients. [PDF]

, 1997
BACKGROUND: More than 50% of patients with Parkinson's disease develop motor response fluctuations (the "wearing off" phenomenon) after more than five years of levodopa therapy.
Baas, H., Beiske, A.G., Ghika, J., Jackson, M., Oertel, W.H., Poewe, W., Ransmayr, G.   +6 more
core   +1 more source

The effect of bedrest on various parameters of physiological function. Part X - The effect of bedrest on the circulatory response to a valsalva maneuver [PDF]

Quantitative arterial blood pressure change during Valsalva maneuver after bed ...
Cardus, D., Spencer, W. A., Vallbona, C., Vogt, F. B.   +3 more
core   +1 more source