Results 31 to 40 of about 839,851 (313)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

On the temporal organization of neuronal avalanches

Frontiers in Systems Neuroscience, 2014
Spontaneous activity of cortex in vitro and in vivo has been shown to organize as neuronalavalanches. Avalanches are cascades of neuronal activity that exhibit a power law in theirand duration distribution, typical features of balanced systems in a ...
Fabrizio eLombardi, Hans eHerrmann, Dietmar ePlenz, Lucilla ede Arcangelis   +3 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

APPLICATION OF MODIFIED CONVERSION METHOD TO A NONLINEAR DYNAMICAL SYSTEM [PDF]

Научно-технический вестник информационных технологий, механики и оптики, 2015
The paper deals with a mathematical model of dynamical system with single degree of freedom, presented in the form of ordinary differential equations with nonlinear parts in the form of polynomials with constant and periodic coefficients.
G.I. Melnikov, S.E. Ivanov, V. G. Melnikov, K.S. Malykh   +3 more
doaj  

Backward bifurcation and oscillations in a nested immuno-eco-epidemiological model

Journal of Biological Dynamics, 2018
This paper introduces a novel partial differential equation immuno-eco-epidemiological model of competition in which one species is affected by a disease while another can compete with it directly and by lowering the first species' immune response to the
Michael Barfield, Maia Martcheva, Necibe Tuncer, Robert D. Holt   +3 more
doaj   +1 more source

Synchronized Beta-Band Oscillations in a Model of the Globus Pallidus - Subthalamic Nucleus Network under External Input

Frontiers in Computational Neuroscience, 2016
Hypokinetic symptoms of Parkinson’s disease are usually associated with the excessively strong oscillations and synchrony in the beta frequency band. The origin of this synchronized oscillatory dynamics is being debated.
SUNGWOO AHN, S. Elizabeth Zauber, Robert M Worth, Leonid L Rubchinsky   +3 more
doaj   +1 more source

On the existence of Hopf bifurcations in the sequential and distributive double phosphorylation cycle

Mathematical Biosciences and Engineering, 2020
Protein phosphorylation cycles are important mechanisms of the post translational modification of a protein and as such an integral part of intracellular signaling and control. We consider the sequential phosphorylation and dephosphorylation of a protein
Carsten Conradi , Elisenda Feliu, Maya Mincheva   +2 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

PERIODIC ATEB-FUNCTIONS AND THE VAN DER POL METHOD FOR CONSTRUCTING SOLUTIONS OF TWO-DIMENSIONAL NONLINEAR OSCILLATIONS MODELS OF ELASTIC BODIES

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
In the process of operation, the simplest elements (hereinafter elastic bodies) of machines and mechanisms under the influence of external and internal factors carry out complex oscillations ‒ a combination of longitudinal, bending and torsion ...
Yaroslav Romanchuk, Mariia Sokil, Leonid Polishchuk   +2 more
doaj   +1 more source