Results 31 to 40 of about 192,144 (268)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
On the temporal organization of neuronal avalanches
Frontiers in Systems Neuroscience, 2014 Spontaneous activity of cortex in vitro and in vivo has been shown to organize as neuronalavalanches. Avalanches are cascades of neuronal activity that exhibit a power law in theirand duration distribution, typical features of balanced systems in a ...
Fabrizio eLombardi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
APPLICATION OF MODIFIED CONVERSION METHOD TO A NONLINEAR DYNAMICAL SYSTEM [PDF]
Научно-технический вестник информационных технологий, механики и оптики, 2015 The paper deals with a mathematical model of dynamical system with single degree of freedom, presented in the form of ordinary differential equations with nonlinear parts in the form of polynomials with constant and periodic coefficients.
G.I. Melnikov +3 more
doaj
Backward bifurcation and oscillations in a nested immuno-eco-epidemiological model
Journal of Biological Dynamics, 2018 This paper introduces a novel partial differential equation immuno-eco-epidemiological model of competition in which one species is affected by a disease while another can compete with it directly and by lowering the first species' immune response to the
Michael Barfield +3 more
doaj +1 more source
Frontiers in Computational Neuroscience, 2016 Hypokinetic symptoms of Parkinson’s disease are usually associated with the excessively strong oscillations and synchrony in the beta frequency band. The origin of this synchronized oscillatory dynamics is being debated.
SUNGWOO AHN +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao +10 more
wiley +1 more source
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Oscillating shells and oscillating balls in AdS [PDF]
Journal of High Energy Physics, 2017 23 pages, 5 figures; v2: refs added; v3: JHEP ...
Banerjee, Avik +3 more
openaire +3 more sources
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie ŚrodowiskaIn the process of operation, the simplest elements (hereinafter elastic bodies) of machines and mechanisms under the influence of external and internal factors carry out complex oscillations ‒ a combination of longitudinal, bending and torsion ...
Yaroslav Romanchuk +2 more
doaj +1 more source