Results 61 to 70 of about 19,117 (160)

Big Data in Cancer Genomics: Computational Foundations and Emerging Pathways for Precision Oncology

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT This review aims to explore the computational foundations of big data in cancer genomics and examine emerging pathways that support precision oncology and personalized cancer care. A narrative review approach was adopted to synthesize evidence from PubMed, Scopus, Web of Science, and IEEE Xplore.
Nur Vanu, Nur Mohammad, Fahad Ahmed, Towsif Alam, Koushik Saha, Durga Shahi, Adib Hossain, Mia Md. Tofayel Gonee Manik, Mst. Rina Parvin   +8 more
wiley   +1 more source

Random block-coordinate methods for inconsistent convex optimisation problems

Fixed Point Theory and Algorithms for Sciences and Engineering, 2023
We develop a novel randomised block-coordinate primal-dual algorithm for a class of non-smooth ill-posed convex programs. Lying midway between the celebrated Chambolle–Pock primal-dual algorithm and Tseng’s accelerated proximal gradient method, we ...
Mathias Staudigl, Paulin Jacquot
doaj   +1 more source

A Re‐Appraisal of Three Network Meta‐Analyses to Explain the Discrepancy in Findings for the Efficacy of Fluoxetine for the Treatment of Depression in Children and Adolescents

Cochrane Evidence Synthesis and Methods, Volume 4, Issue 6, November 2026.
ABSTRACT Objective To explain discrepant findings for fluoxetine's efficacy in three influential network meta‐analyses (NMAs) of treatments for pediatric depression, which led to conflicting clinical recommendations. Design Critical appraisal and re‐analysis of three published NMAs.
Richard Lyus, Florian Naudet, Gert van Valkenhoef, Martin Plöderl   +3 more
wiley   +1 more source

Comments on Plutarch’s essay On Isis and Osiris

, 2020
This compressed and selective commentary, with special reference to wording about the sōma ‘body’ of Osiris, features summaries, paraphrases, and quotations of Plutarch’s key formulations.
Nagy, Gregory
core   +4 more sources

Common volume satellite studies of polar mesospheric clouds with Odin/OSIRIS tomography and AIM/CIPS nadir imaging [PDF]

Atmospheric Chemistry and Physics, 2019
Two important approaches for satellite studies of polar mesospheric clouds (PMCs) are nadir measurements adapting phase function analysis and limb measurements adapting spectroscopic analysis.
L. Broman, S. Benze, J. Gumbel, O. M. Christensen, C. E. Randall   +4 more
doaj   +1 more source

A Revision of Australian Anchiale Stål, 1875 (Phasmida: Phasmatidae), with the Description of Two New Species

Austral Entomology, Volume 65, Issue 4, November 2026.
ABSTRACT The Australian species of the Phasmida genus Anchiale Stål, 1875 (Phasmatinae: Phasmatini) are updated to include five species: Anchiale albopunctata (Kirby, 1896) stat. rev. (removed from synonymy with A. briareus (Gray, 1834)); A. briareus Gray, 1834 (= Ctenomorpha tessulata Gray, 1835 syn. nov.; = A. austrotessulata Brock & Hasenpush, 2007,
Braxton R. Jones, Paul D. Brock, Ross M. Coupland, Angus Emmott, Nathan Lo   +4 more
wiley   +1 more source

Generative unsupervised downscaling of climate models via domain alignment: Application to wind fields

Environmental Data Science
General circulation models (GCMs) are widely used for future climate projections, but their coarse spatial resolution and systematic biases limit their direct use for impact studies. This limitation is particularly critical for wind-related applications,
Julie Keisler, Boutheina Oueslati, Anastase Charantonis, Yannig Goude, Claire Monteleoni   +4 more
doaj   +1 more source

From Flybys to Sample Return: A Review of Space Probes and Robotic Sampling Technologies for Small Bodies

Journal of Field Robotics, Volume 43, Issue 7, Page 4475-4514, October 2026.
ABSTRACT As a crucial puzzle piece of deep space exploration, exploring small bodies can provide significant scientific insights and valuable mineral resources. Unlike missions to the Moon and Mars, small‐body missions pose distinct technical challenges, including communication delays, weak gravity, and uncertain environments. This paper reviews a full
Xin Zhang, Hao Zhou, Dalin Zhou, Zhaojie Ju   +3 more
wiley   +1 more source

Novel Flavonoid Senotherapeutics Identified by Phenotypic Drug Discovery Reduce Senescence and Improve Multiple Markers of Healthspan

Aging Cell, Volume 25, Issue 10, October 2026.
Phenotypic screening and SAR‐guided drug design identified two flavonoid‐derived senolytics, SR29384 and SR31133, which selectively killed different types of senescent cells more efficiently and with greater selectivity than fisetin in culture. In aged and progeroid mice, these fisetin analogs reduced tissue senescence and improved physical function ...
Lei Justan Zhang, Rahagir Salekeen, Carolina Soto‐Palma, Qiuming Wu, Yuanjun He, Osama Elsallabi, Bilel Bdiri, Brian Hughes, Allancer Nunes, Wandi Xu, Borui Zhang, Abdalla Mohamed, Sara J. McGowan, Luise Angelini, Ryan O'Kelly, Theodore M. Kamenecka, Laura J. Niedernhofer, Paul D. Robbins   +17 more
wiley   +1 more source

PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation

International Journal of Dermatology, Volume 65, Issue 10, Page 2038-2048, October 2026.
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad, Nicole E. Chin, Raj Chovatiya   +2 more
wiley   +1 more source