Results 51 to 60 of about 96,564 (283)

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Reported Radioactivity of Osmium [PDF]

Nature, 1948
FOR some time it has been known that two isobars which differ by unity in atomic number cannot both be stable, except for a possible influence of the neutrino if its mass has a positive value at rest. A search for radioactivity among the existing pairs of isobars led to the announcement1 of K-electron capture in osmium (Os187) with a half-life of about
openaire   +2 more sources

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu, Wenjing Xian, Mengxue Wang, Guozhi Zhao, Yanhuo Zhang, Zhiyu Zhou, Bo Sheng, Zhuo Zhen, Xie Liu, Shouwen Diao, Mengwei Tu, Chen Qiu, Huixian Wang, Jianbo Zhang, Peng Zhu, Tong Li   +15 more
wiley   +1 more source

The use of osmium-thiocarbohydrazide-osmium (OTO) and ferrocyanide-reduced osmium methods to enhance membrane contrast and preservation in cultured cells.

, 1984
The preservation and contrast of membranous structures in cultured cells using various postfixation procedures prior to embedding have been investigated.
M C Willingham, A V Rutherford
core   +1 more source

Tracking Reactions of Asymmetric Organo‐Osmium Transfer Hydrogenation Catalysts in Cancer Cells [PDF]

, 2021
Elizabeth M. Bolitho, James P. C. Coverdale, Hannah E. Bridgewater, Guy J. Clarkson, Paul D. Quinn, Carlos Sánchez-Cano, Peter J. Sadler   +6 more
openalex   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Osmium in seawater : analysis and geochemistry

, 1998
A method for the direct analysis of seawater osmium has been developed and is described in this thesis. Low and constant blanks are obtained (0.12 pg osmium with 187Os/186Os=2.6) and spike-sample equilibration is achieved using this method.A 191Os ...
Woodhouse, Oliver Brian
core  

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Electronic structures of osmium dinitrides and dinitrogen molecule activation by the osmium atom

, 2002
Density functional theory and ab initio electron-correlation methods have been used to study structures, stabilities, and bonding properties of osmium dinitrides, and possible mechanisms for the direct insertion of osmium into the strong dinitrogen ...
吴玮, 张乾二, Zhang, QN, Wu, W, Cao, ZX, 曹泽星   +5 more
core  

Don't Store Osmium Tetroxide in Plastic Containers

, 2000
It is not safeto store osmium in ordinary laboratory plastic containers. Osmium penetrates polyolefin plastics (polyethylene, polypropylene) to some depth, and reacts with them, so containers made from these plastics or of polystyrene or polycarbonate ...
Chris Jeffree
core   +1 more source