Results 231 to 240 of about 84,971 (337)

Pinellia pedatisecta Schott‐Derived Exosome‐Like Nanovesicles Promote Apoptosis in Colorectal Cancer by Regulating the Lysosome‐Mediated Mitophagy Pathway

open access: yesFood Science &Nutrition, Volume 14, Issue 2, February 2026.
Pinellia pedatisecta Schott‐derived exosome‐like nanovesicles (PPS‐ELNs) are efficiently taken up by colorectal cancer (CRC) cells and exhibit tumor‐targeting properties. Mechanistically, PPS‐ELNs suppress tumor progression by inhibiting the proliferation of CRC cells and promoting apoptosis through regulation of the lysosome‐mediated mitophagy pathway.
Pingsheng Zhou   +4 more
wiley   +1 more source

The Capsular Polysaccharides GXM and GXMGal from <i>Cryptococcus neoformans</i> Modulate Macrophages Infected with <i>Leishmania major</i>. [PDF]

open access: yesMicroorganisms
Ferreira-Dos-Santos IM   +17 more
europepmc   +1 more source

Osmium Tetroxide and Its Applications

open access: yesPlatinum Metals Review, 1974
openaire   +1 more source

Acute Intermittent Hypoxia Exerts Beneficial Effects and Promotes Repair in Male Mice in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis

open access: yesGlia, Volume 74, Issue 2, February 2026.
Acute intermittent hypoxia is a novel, noninvasive therapy that shows promising and similar beneficial repair and remyelination following demyelination in male experimental autoimmune encephalomyelitis, as was previously shown in female mice. ABSTRACT Multiple sclerosis (MS) affects women more frequently than men, but the disease progresses more ...
Nataliya Tokarska   +6 more
wiley   +1 more source

Crotoxin Elicits Differential Increases in Macrophage Lipid Droplet Formation In Vitro Modulated during <i>Leishmania (Leishmania) amazonensis</i> Infection. [PDF]

open access: yesACS Omega
Ávila LT   +8 more
europepmc   +1 more source

Differentiating Damp‐Heat and Cold‐Damp Diarrhea in Rat Models via Gut Microbiota Dysbiosis and Short‐Chain Fatty Acid Profiling

open access: yesMicrobiologyOpen, Volume 15, Issue 1, February 2026.
ABSTRACT On the basis of gut microbiota and short‐chain fatty acids (SCFAs), this study aims to identify diagnostic biomarkers for damp‐heat diarrhea and cold‐damp diarrhea. Rat models of damp‐heat diarrhea and cold‐damp diarrhea were established. Changes in body weight, body temperature, food intake, water consumption, and the diarrhea index were ...
Hao Zhang   +5 more
wiley   +1 more source

Bone marrow adipose tissue expansion and bone loss in experimental chronic kidney disease is independent of altered bone marrow stromal cell lineage determination. [PDF]

open access: yesFront Endocrinol (Lausanne)
Promruk W   +7 more
europepmc   +1 more source

BvrR From Brucella abortus Induces Neuroinflammation Through IRE1‐Mediated Activation of ATF2 and NF‐κB

open access: yesMicrobiologyOpen, Volume 15, Issue 1, February 2026.
This study demonstrates that the BvrR induces neuroinflammation. In microglial cells, BvrR expression localizes to the endoplasmic reticulum (ER), causing ER expansion and activating the stress sensor IRE1. Phosphorylated IRE1 subsequently drives the activation and nuclear translocation of transcription factors ATF2 and NF‐κB p65.
Zhao Wang   +3 more
wiley   +1 more source

Integrative Single‐Cell Analysis Reveals Targetable Vacuole Membrane Protein 1‐Mediated Mechanism of Tumor Angiogenesis in Glioblastoma

open access: yesMedComm, Volume 7, Issue 2, February 2026.
VMP1 promotes angiogenesis in glioblastoma (GBM) through VEGFA‐VEGFR2 signaling and activation of endothelial cells. The FDA‐approved anti‐VEGFA antibody, bevacizumab (BEV), can counteract VMP1's tumor‐promoting effect in GBM. Targeting VMP1 or its associated pathways could be a new therapeutic strategy, either alone or in combination with BEV.
Lei Jin   +8 more
wiley   +1 more source

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