Results 161 to 170 of about 9,863 (273)

An edge β‐strand mutation turns ubiquitin into a pore‐forming amyloid

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Ubiquitin (Ub) is a highly conserved eukaryotic protein, generally regarded as stable and soluble under physiological conditions, playing a key role in maintaining cellular protein balance. Using complementary bioinformatic, biophysical, immunochemical, and electrophysiological approaches, we show that a single point mutation—the substitution ...
Daniela Meleleo, Rosanna Mallamaci, Vincenza Calò, Maurizio Losacco, Vincenzo Mangini, Fabio Arnesano   +5 more
wiley   +1 more source

Incidence of acute kidney injury among high-risk adult patients undergoing iso-osmolar contrasted computed tomography scans: a prospective cohort study. [PDF]

Afr Health Sci
Nakku M, Muyinda Z, Nabbosa V, Mubuuke AG, Baluku JB, Babirye D, Walubembe J, Angom DO, Nalwoga K, Kalyesubula R.   +9 more
europepmc   +1 more source

Transient hyperthyroxinemia in symptomatic hyponatremic patients

, 1986
Twenty-two patients with severe hyponatremia were divided into 12 patients with and ten without associated neurologic manifestations (groups 1 and 2, respectively).
Abramow, Maurice, Cogan, Elie
core  

Wafer‐Scale Deterministic Fabrication of Axis‐Ratio–Engineered Silicon Nanoparticles for On‐Resonance Electric–Magnetic Dipole Interference

Small, Volume 22, Issue 32, 8 June 2026.
Wafer‐scale top‐down fabrication yields silicon nanoparticles with exceptional uniformity (CV 1.7%–2.4%), enabling deterministic axis‐ratio tuning. At AR ≈$\approx$ 2.1, electric–magnetic dipoles overlap on‐resonance, producing near‐Kerker forward scattering (F/B ≈$\approx$ 12.5).
Taeyeong Kim, Jungchul Lee
wiley   +1 more source

Serum osmolarity as a predictor of mortality in ICU COVID-19 patients: a retrospective analysis. [PDF]

PeerJ
Toptas M, Dikme Ö, Dikme O, Tünay A, Yilmaz Cakirgoz M, Akkoç İ.   +5 more
europepmc   +1 more source

Ocular surface disease in atopic dermatitis

Acta Ophthalmologica, Volume 104, Issue S291, Page S4-S28, June 2026.
ENGLISH SUMMARY Atopic keratoconjunctivitis (AKC) is a severe ocular surface disease (OSD) that significantly affects patients' quality of life and can lead to blindness. AKC is associated with atopic dermatitis (AD), a common chronic inflammatory skin disease affecting both children and adults.
Pernille May Hansen
wiley   +1 more source

Anal Sex and Tenofovir Douche Sequence Impacts Colorectal Distribution of HIV Surrogate and Douche: DREAM-02. [PDF]

J Infect Dis
Zheng R, Fuchs EJ, Nimmagadda S, Rohan LC, Wang L, Bertagnolli LN, Massih S, Caffo BS, Hendrix CW.   +8 more
europepmc   +1 more source

The Recycling Endosomal (Na+, K+)/H+ Exchanger NHE6/SLC9A6 Facilitates Signal Transduction by Shuttling Cyclin‐Dependent Kinase 5 to the Plasma Membrane

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The alkali cation/proton exchanger NHE6/SLC9A6 regulates luminal pH homeostasis and trafficking of recycling endosomes in most tissues, especially neurons. Loss‐of‐function mutations in NHE6 cause Christianson Syndrome, an X‐linked neurodevelopmental and neurodegenerative disorder; however, the underlying molecular and cellular mechanisms ...
Rebecca Flessner, Alina Ilie, Léo Han, Annie Boucher, Rebecca Anne McKinney, Reza Sharif‐Naeini, John Orlowski   +6 more
wiley   +1 more source

Acute Adverse Reactions to Nonionic Low-Osmolar Iodinated Contrast Media in Children: A Retrospective Study of 23,429 Injections Over 6 Years. [PDF]

Korean J Radiol
Seong Y, Kim PH, Suh CH, Park KJ, Park HJ, Lee CW, Jung AY, Cho YA, Lee JS, Yoon HM.   +9 more
europepmc   +1 more source

Mechanism of Fluid Reabsorption in Kidney Proximal Tubule: Interplay Between Lateral Na+/K+‐ATPase and AQP1 and SGLT1 Mediated Water Fluxes

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aims The mechanism of isosmotic water reabsorption in the kidney proximal tubule, with a focus on the interaction between the lateral Na+/K+‐ATPase, apical water pathways mediated by AQP1 and SGLT1, and paracellular water flow through Claudin‐2. Methods A mathematical model of proximal tubular transport was used to compute coupled ion, solute,
Erik Hviid Larsen, Jens Nørkær Sørensen   +1 more
wiley   +1 more source