Results 141 to 150 of about 9,863 (273)

Contrast‐enhanced CT—Nephrotoxic or not? A critical review of propensity‐score‐adjusted studies

Journal of Internal Medicine, Volume 300, Issue 1, Page 5-25, July 2026.
Abstract Retrospective, propensity‐score‐adjusted (PSA) studies have indicated to practitioners in the field that contrast‐induced acute kidney injury (AKI) after contrast‐enhanced CT (CECT) is of minor importance or even non‐existent. This has led to controversies between clinicians demanding CECT not to miss any diagnoses and radiologists reluctant ...
Ulf Nyman, Jonas Björk, Mikael Hellström, Peter Leander, Per Liss, Gunnar Sterner, Torkel B. Brismar   +6 more
wiley   +1 more source

A General Strategy for the Synthesis of Jerangolids Enabled by π‐allyl Stille Coupling

Chemistry – A European Journal, Volume 32, Issue 23, 16 June 2026.
A general strategy for the synthesis of jerangolids is established, featuring a late‐stage π‐allyl Stille coupling of two advanced, highly customizable building blocks to form the skipped diene core. The approach provides access to all naturally occurring jerangolids, including jerangolid H, whose configuration is confirmed by NMR analysis.
Janick Schug, Bernd Morgenstern, Johann Jauch   +2 more
wiley   +1 more source

Let There be Light! Light as an Engine and Regulator in Synthetic Cells

Angewandte Chemie International Edition, Volume 65, Issue 24, 8 June 2026.
Cells are out‐of‐equilibrium systems that regulate their spatiotemporal features. In biomimetic synthetic cells, light offers a unique way for energizing and regulating events in space and time. This review explores the implementation of light‐responsive tools in synthetic cells to replicate biological functions and enable new bioinspired behaviors ...
Matthew E. Allen, Saskia Frank, Mehaiarii Louis, Atreyee Saha, Ali Heidari, Seraphine V. Wegner   +5 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, Volume 20, Issue 6, Page 1420-1428, June 2026.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

Advanced Science, Volume 13, Issue 34, 19 June 2026.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen, Qimeng Wang, Ke Yang, Qinghai Lian, Xuyun Peng, Zhiyong Gong, Xinyi Zhao, Yong Wu, Tian Tao, Siqi Xu, Yifan Chen, Xiaoyan Tang, Jinghui Guo, Geyang Xu, Qi Zhang   +14 more
wiley   +1 more source

Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output

Advanced Science, Volume 13, Issue 34, 19 June 2026.
Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin, Shulan Xiao, Krishna Jayant   +2 more
wiley   +1 more source

Severe ethylene glycol intoxication with marked lactate and osmolar gaps leading to acute kidney injury: a case report. [PDF]

Int J Emerg Med
Kitawara KAH, Cerqueira BP, Balda CA, Rangel ÉB.   +3 more
europepmc   +1 more source

Osteogenic Potential of a Three‐Phase Strontium‐ and Silicon‐Doped Tricalcium Silicate Cement on Dental Pulp Stem Cells: An In Vitro Study

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objective This study aimed to evaluate the osteogenic potential of a novel three‐phase cement composed of strontium‐doped hydroxyapatite (Sr‐HA), silicon‐doped hydroxyapatite (Si‐HA), and tricalcium silicate (C3S) on dental pulp stem cells (DPSCs) in vitro.
Nahid Nasrabadi, Ehsan Saburi, Hossein Bagheri, Atekeh Hosseinpour, Mahsa Ghorbani, Pooya Saeedi   +5 more
wiley   +1 more source

Poor compliance of recurrent stone formers to increase their fluid intake in spite of repeated recommendation. [PDF]

Clin Kidney J
Bankir L, Daudon M.
europepmc   +1 more source

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, Volume 255, Issue 6, Page 567-584, June 2026.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source