Results 41 to 50 of about 13,143 (258)

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Central pontine myelinolysis and its differential diagnoses in a pregnant woman with diabetes: case report and literature review

Revista Brasileira de Saúde Materno Infantil
Introduction: central pontine myelinolysis (CPM) is characterized by the destruction of the myelin sheath from oligodendrocytes due to a rapid increase in plasma osmolarity and consequent passage of components through the blood-brain barrier ...
Danielle Medeiros Urquiza, Alex Sandro Rolland Souza, Giovanna Macedo Tavares, Gustavo Fonseca de Albuquerque Souza, Leila Katz   +4 more
doaj   +2 more sources

A Simple Predictive Factor for Mortality in Fontan Surgery: Serum Hypo-Osmolality [PDF]

Brazilian Journal of Cardiovascular Surgery
Objective: Close follow-up is important after the Fontan procedure, which is a palliative surgical method for a single ventricle. In this period, serum osmolality is an important parameter with the advantages of easy to obtain and poor outcome prediction.
Baburhan Ozbek, Nursen Tanrıkulu
doaj   +2 more sources

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

Advanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen, Qimeng Wang, Ke Yang, Qinghai Lian, Xuyun Peng, Zhiyong Gong, Xinyi Zhao, Yong Wu, Tian Tao, Siqi Xu, Yifan Chen, Xiaoyan Tang, Jinghui Guo, Geyang Xu, Qi Zhang   +14 more
wiley   +1 more source

Bottom‐Up Coacervate‐Based Artificial Cells: Integrating Cellular Hallmarks into Complex Life‐Like Systems

Angewandte Chemie, EarlyView.
Current interest in artificial cell research underscores its potential to deepen our understanding of life's fundamental processes. This review highlights advances in bottom‐up coacervate‐based artificial cell engineering via combined integration of cellular hallmarks.
Arjan Hazegh Nikroo, Angshuman Das, Madelief A. M. Verwiel, Jan C. M. van Hest   +3 more
wiley   +2 more sources

Clinical profile of patients with hyponatremia in a tertiary care hospital in the sub-Himalayan region

Journal of Family Medicine and Primary Care, 2020
Introduction: Hyponatremia, defined as a serum sodium concentration ([Na+])
Nikhil Sood, Kailash Nath Sharma, Pratibha Himral, Tarun Sharma, Dhiraj Kapoor   +4 more
doaj   +1 more source

Radical‐Mediated, Substrate‐Independent Fabrication of Hybrid Solid–Hydrogel Materials With Tunable Crosslinking: An Initiator‐ and Crosslinker‐Free Approach

Advanced Science, EarlyView.
This work introduces a substrate‐independent, reagent‐free plasma strategy that forms radical‐rich interlayers for covalent hydrogel attachment without initiators or crosslinkers. The long‐lived radicals drive in situ gelation, creating robust, cytocompatible hybrid solid–hydrogel constructs across diverse substrates.
Ghazal Shineh, Azin Khodaei, Pardis Keikhosravani, Masoud Zhianmanesh, Yiyun Xia, Aaron Gilmour, Sina Naficy, Andrea Guzina, Daniella Bianchi, Khoon S. Lim, Fariba Dehghani, Saber Amin Yavari, Marcela Bilek, Giselle C. Yeo, Behnam Akhavan   +14 more
wiley   +1 more source

СOMPARISON OF LOW- AND HIGH-CONCENTRATION (270 AND 320 MG I/ML) ISO-OSMOLAR IODINATED CONTRAST MEDIA IN CORONARY CT ANGIOGRAPHY: A RANDOMIZED PROSPECTIVE SINGLE-CENTER BLINDED STUDY

Вестник рентгенологии и радиологии, 2016
Objective: to compare the image quality at coronary multidetector computed tomography (MDCT) using low-dose and lowiodine protocol study in comparison with the standard protocol.Material and methods.
V. E. Sinitsyn, M. A. Komarova, E. A. Mershina   +2 more
doaj   +1 more source

Acute severe thrombocytopenia following non-ionic low-osmolarity intravenous contrast medium injection [PDF]

, 2012
Intravenous contrast medium (ICM) rarely induces anaphylactic reactions, including urticaria, hypotension and respiratory failure. Even the most modern ICM may cause such adverse events.
Adam Domonkos Tarnoki, Aster, Bonnard, Chang, David Laszlo Tarnoki, Evelin Horvath, Ferenc Szalay, Hunt, Lacy, Pal Bata, Schulze, Shojania, Ural, Viktor Berczi, Wein, Wiemer   +15 more
core   +1 more source

Light-Absorbing Properties and Osmolarity of Indocyanine-Green Depending on Concentration and Solvent Medium

Investigative Opthalmology & Visual Science, 2003
To evaluate the absorption spectrum and osmolarity of three currently used indocyanine green (ICG) products at different concentrations and with different solvent media.The absorption spectrum and osmolarity of three different ICG products (Pulsion, Munich, Germany; Akorn, Buffalo Grove, IL; and Laboratoires SERB, Paris, France) were analyzed. Each ICG
Christos, Haritoglou, Arnd, Gandorfer, Markus, Schaumberger, Ramin, Tadayoni, Achim, Gandorfer, Anselm, Kampik   +5 more
openaire   +2 more sources