Frontiers in Physiology, 2013 In asthmatic patients, inhalation of hyperosmolar saline or D-mannitol (D-M) elicits bronchoconstriction, but in healthy subjects exercise causes bronchodilation. Hyperventilation causes drying of airway surface liquid (ASL) and increases its osmolarity.
Jeffrey S. Fedan +3 more
doaj +1 more source
Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study [PDF]
, 2019 Background: Dry eye disease (DED) affects more than 14% of the elderly population causing decrease of quality of life, high costs and vision impairment.
Allegretti, M. +7 more
core +1 more source
Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects
Animal Models and Experimental Medicine, EarlyView.Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu +12 more
wiley +1 more source
TURP Syndrome and Changes in Body Fluid Distribution [PDF]
, 2001 前立腺肥大症の経尿道的前立腺切除術では潅流液に3%のソルビトール液を用いるために,破綻した血管から吸収された潅流液により低ナトリウム性のTUR症候群を起こすことが知られている.潅流液の吸収による体液バランスの変化を61名の患者で測定した.吸収潅流液（V-abs),出血量（B-loss）,細胞内液増加量（ΔICF）,細胞外液増加量（ΔECF）を検査データから計算により求めた.TUR症候群を来した患者群（TURS）と無症状患者群（ASTM）に分けた.出血量はTURS（平均860 ml）がASTM ...
宮尾 秀樹 +4 more
core
Morphological instability of a nonequilibrium icecolloid interface [PDF]
, 2009 We assess the morphological stability of a nonequilibrium icecolloidal suspension interface, and apply the theory to bentonite clay. An experimentally convenient scaling is employed which takes advantage of the vanishing segregation coefficient at low ...
Majumdar, A. +2 more
core +3 more sources
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
Advanced NanoBiomed Research, EarlyView.This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Tear osmolarity and tear function assessment in patients with polycystic ovary syndrome
Revista Brasileira de OftalmologiaPurpose: Polycystic ovary syndrome (PCOS) is an endocrine disease characterized by chronic anovulation and hyperandrogenism. Hormonal changes can affect tear function.
Derya Alp Guliyev +6 more
doaj +1 more source
Selective Osmotic Shock for Islet Isolation in the Cadaveric Canine Pancreas
Cell Transplantation, 2018 Currently, islet isolation is performed using harsh collagenases that cause nonspecific injury to both islets and exocrine tissue, negatively affecting the outcome of cell transplantation.
Elizabeth M. Thompson +3 more
doaj +1 more source
The potential effect of low cell osmolarity on cell function through decreased concentration of enzyme substrates [PDF]
Journal of Experimental Botany, 2018 Some freshwater algae have lower (180 osmol m-3). Low osmolarities are related to the presence of flagella and the low energy cost of active water efflux following downhill water influx unconstrained by cell walls covering the plasmalemma, and the low resource cost of cell wall synthesis with the same mechanical degree of safety. One consequence of low
openaire +3 more sources
Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction
Advanced NanoBiomed Research, EarlyView.In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen +14 more
wiley +1 more source