Results 81 to 90 of about 6,598,473 (249)

Reliability of Reagent Strips in Veterinary Medicine: A Critical Evaluation of pH and Urinary Density in Dogs using Statistical Modeling

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT Background Urinalysis is a simple and essential test in veterinary practice, involving physical, chemical, and microscopic analysis of urine. Reagent strips are widely used due to their practicality; however, their reliability compared with reference laboratory methods remains a subject of debate.
Cleber F. M. Mansano   +5 more
wiley   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu   +2 more
wiley   +1 more source

A TREK‐1/AQP4/TRPA1/BDNF Signaling Axis Is Associated With Astrocytic Volume Transients, Synaptic Plasticity, and Spatial Memory

open access: yesGlia, Volume 74, Issue 9, September 2026.
Astrocytic TREK‐1‐dependent volume transients contribute to hippocampal synaptic plasticity and memory formation. TRPA1‐mediated astrocytic calcium signaling is required for long‐term potentiation, while astrocytic BDNF is necessary and sufficient to support sustained synaptic plasticity.
Victor James Drew   +6 more
wiley   +1 more source

Fasting before contrast-enhanced CT and the incidence of acute adverse reactions: a single-center randomized clinical trial

open access: yesInsights into Imaging
Objectives To evaluate the effect of eliminating the traditional preparatory fasting policy before contrast-enhanced CT on acute adverse reactions and to identify potential risk factors in a Spanish population sample, since many European patients still ...
Laila Zitan Saidi   +5 more
doaj   +1 more source

Navigating Human Astrocyte Differentiation: Direct and Rapid One‐Step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network Development

open access: yesGlia, Volume 74, Issue 9, September 2026.
One‐step protocol enabling direct differentiation of human iPSCs into functional astrocytes within 5 weeks. Validated in > 60 lines across 10 labs. iPSC‐astrocytes support robust neuronal network development in co‐culture. ABSTRACT Astrocytes play a pivotal role in neuronal network development.
Imke M. E. Schuurmans   +39 more
wiley   +1 more source

Semi‐Automated μCT‐Based Modeling of Vertebral Bony Endplate Microporosity and Mechanical Properties: Linking Microstructure to Inferred Mechanical Performance

open access: yesJOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT Background The vertebral bony endplate (BEP) plays a role in regulating both mechanical load transfer and nutrient transport to the intervertebral disc, functions strongly influenced by its microstructural porosity. Variations in porosity impact bone strength, elasticity, and solute diffusion, affecting its overall mechanical competence ...
Ahmad Alminnawi   +5 more
wiley   +1 more source

Surviving the Nucleus Pulposus Desert: Next‐Generation Strategies for Intervertebral Disc Cell Therapy

open access: yesJOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACTBackgroundLow back pain remains the leading cause of disability worldwide, with intervertebral disc degeneration representing a major biological contributor. Although cell‐based therapies have shown promise in preclinical models, clinical translation has yielded modest and inconsistent outcomes.
Tynhinane Hamidouche   +9 more
wiley   +1 more source

Mito‐TEMPO Improves Post‐Thaw Quality and Fertilizing Capacity of Rooster Semen Cryopreserved in Beltsville Extender

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study reported the effect of Mito‐TEMPO on rooster semen quality cryopreserved in Beltsville extender. Semen diluted in extenders containing 10 or 100 µM of Mito‐TEMPO presented higher motility, average path velocity as well as membrane/acrosome integrity, mitochondrial activity, and fertility rate; and lower lipid peroxidation, apoptosis rate ...
Mahdi Mokhtari   +3 more
wiley   +1 more source

Limited Utility of a Test‐Yolk Buffer Semen Extender for Preserving Human Semen Parameters for Use in a Diagnostic Setting

open access: yesAndrology, Volume 14, Issue 6, Page 1701-1711, September 2026.
ABSTRACT Background Identification of a preservation medium that accurately retains semen parameters would be advantageous for men requiring semen analysis by allowing them to produce sperm samples at home rather than on site or even facilitate ‘mail order’ semen analysis.
Alessia Schadwell   +5 more
wiley   +1 more source

Limited Efficacy of Autologous Mesenchymal Stromal Cell Injections in Immunomodulatory‐Dependent Dogs With Aqueous Deficient Dry Eye Disease

open access: yesVeterinary Ophthalmology, Volume 29, Issue 5, September 2026.
ABSTRACT Objective Aqueous deficient dry eye disease (ADDE) results from a quantitative reduction in aqueous tears. We sought to determine the clinical effect of autologous mesenchymal stromal cell (MSC) injections into the region of the lacrimal gland and the gland of the third eyelid in immunomodulatory‐dependent ADDE‐affected dogs. Methods Dogs (n = 
Brian C. Leonard   +9 more
wiley   +1 more source

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