Results 41 to 50 of about 60,903 (296)

Protein nanoparticles induce the activation of voltage-dependent non-selective ion channels to modulate biological osmotic pressure in cytotoxic cerebral edema

Frontiers in Pharmacology
IntroductionCytotoxic cerebral edema is a serious complication associated with cerebral ischemic stroke and is widely treated using the hypertonic dehydrant.
Wei Fan, Liming Liu, Yuxuan Yin, Jiayi Zhang, Zhaoshun Qiu, Jun Guo, Guangming Li   +6 more
doaj   +1 more source

Biaxial testing of canine annulus fibrosus tissue under changing salt concentrations

Anais da Academia Brasileira de Ciências, 2010
The in vivo mechanics of the annulus fibrosus of the intervertebral disc is one of biaxial rather than uniaxial loading. The material properties of the annulus are intimately linked to the osmolarity in the tissue.
Jacques M. Huyghe
doaj   +1 more source

CONSUMERS'ACCEPTANCE OF FRESH AND COMBINED METHODS PROCESSED MELON, MANGO AND CASHEW APPLE [PDF]

Revista Brasileira de Fruticultura, 2001
Fresh and combined methods processed Cantaloupe melons, mangoes and cashew apples were submitted to consumers' acceptance and scored on a nine-point hedonic scale. Fruits were osmotically treated in sucrose syrup with two different concentrations of SO2.
RENATA TIEKO NASSU, JANICE RIBEIRO LIMA, MEN DE SÁ MOREIRA DE SOUZA FILHO   +2 more
doaj   +1 more source

Combined Pulsed Vacuum Osmotic Dehydration and Convective Air-Drying Process of Jambolan Fruits

Foods, 2023
Jambolan (Syzygium cumini) is a native fruit from Asia that has adapted well to the tropical climate of the Amazonian region. However, due to its limited annual availability and high perishability, the jambolan fruit is still underexploited.
Adriano Lucena de Araújo, Rosinelson da Silva Pena   +1 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Experimental Paradigm for the Assessment of the Non-pharmacological Mechanism of Action in Medical Device Classification: The Example of Glycerine as Laxative

Frontiers in Pharmacology, 2018
The evolution of medical devices has led to the introduction of medical devices that include “substances” and which, due to their presentation and sites of application may resemble medicinal products.
Claudia Sardi, Stefano Garetto, Laura Capone, Valentina Galbiati, Marco Racchi, Stefano Govoni, Emiliano Giovagnoni, Jacopo Lucci   +7 more
doaj   +1 more source

Dynamics of osmosis in a porous medium [PDF]

Royal Society Open Science, 2014
We derive from kinetic theory, fluid mechanics and thermodynamics the minimal continuum-level equations governing the flow of a binary, non-electrolytic mixture in an isotropic porous medium with osmotic effects.
Silvana S. S. Cardoso, Julyan H. E. Cartwright   +1 more
doaj   +1 more source

Osmotic Pump Drug Delivery Systems—A Comprehensive Review

Pharmaceuticals, 2022
In the last couple of years, novel drug delivery systems (NDDS) have attracted much attention in the food and pharmaceutical industries. NDDS is a broad term that encompasses many dosage forms, one of which is osmotic pumps.
Yosif Almoshari
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Stretchable carbon actuator using induced charge electro-osmosis [PDF]

, 2021
Stretchability via structural changes is important for many products. In this study, we report that conductive carbon mesh material that was made by the self-organization process using induced charge electro-osmosis (ICEO) under DC electric fields shows ...
Sugioka, Hideyuki, Nakamura, Hiroya, Kado, Taiki   +2 more
core   +1 more source