Results 131 to 140 of about 144,399 (288)
Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang +7 more
wiley +1 more source
Identification of PKN2 and MOB4 as Coordinators of Collective Cell Migration
Through a genetic screen, PKN2 and MOB4 are identified as two proteins regulating the healing of an epithelial model wound. PKN2 promotes collective cell migration by maintaining the cohesion of cell monolayers from their lateral junctions, whereas MOB4 restrains collective cell migration and provides a lamellipodial cue for front‐rear polarity in ...
Artem I. Fokin +7 more
wiley +1 more source
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li +7 more
wiley +1 more source
Ultra‐High Friction and Adhesion in Hydrogel Layer Driven by Wet‐to‐Dry Transition Dynamics
This work reveals a critical wet‐to‐dry transition in polyacrylamide hydrogel layers that induces volumetric shrinkage, resulting in enhanced interfacial contact and dramatically increased friction and adhesion. Leveraging this transition enables strong, reversible gripping on diverse surfaces, offering new insights for hydrogel‐based gripping ...
Chenxu Liu +11 more
wiley +1 more source
Do Daily and Seasonal Changes in Non-Structural Carbohydrates in Grapevine Leaves Contribute to Osmotic Adjustment and Regulation of Photosynthesis? [PDF]
Perry A +5 more
europepmc +1 more source
Single‐Cell Metabolic Imaging Reveals Glycogen‐Driven Adaptations in Endothelial Cells
Single‐cell metabolic imaging of diabetes‐associated endothelial dysfunction by SRS microscopy reveals dynamic glycogen storage and its role in modulating metabolic adaptations under glucose starvation. Abstract Endothelial dysfunction (ED) is a defining feature of diabetes mellitus (DM) and a key contributor to many metabolic and cardiovascular ...
Rahuljeet S. Chadha +13 more
wiley +1 more source
Dewatering Hypersaline Na<sub>2</sub>SO<sub>4</sub> and NaCl via Commercial Forward Osmosis Module. [PDF]
Devaere N, Papangelakis VG.
europepmc +1 more source
Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells
The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot +2 more
wiley +1 more source

