Results 121 to 130 of about 4,733,198 (287)

Cholesterol Laundry of Cell Membrane and Fatty Liver by Detergent Liposomes to Improve Anti‐Cancer Drug Responsiveness of Patient Liver Tissues

Advanced Science, EarlyView.
Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim, Joo Kyung Noh, Sewoom Baek, Seung Eun Yu, Jueun Kim, Seongyo Lee, Youngji Oh, Dai Hoon Han, Seyong Chung, Hak‐Joon Sung   +9 more
wiley   +1 more source

Targeting the HSPA8‐CMA‐ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer

Advanced Science, EarlyView.
Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An, Ze Gao, Shuo Chen, Liwei Meng, Chen Zhang, Kefan Song, Haochen Cui, Lei Yan, Zhiqing Fang   +8 more
wiley   +1 more source

Permeability and selectivity synergistically enhanced nanofluidic membrane for osmotic energy harvesting

Carbon Energy
For the porous‐membrane‐based osmotic energy generator, the potential synergistic enhancement mechanism of various key parameters is still controversial, especially because optimizing the trade‐off between permeability and selectivity is still a ...
Jundong Zhong, Tingting Xu, Hongyan Qi, Weibo Sun, Shuang Zhao, Zhe Zhao, Yirong Sun, Youliang Zhu, Jianxin Mu, Haibo Zhang, Xuanbo Zhu, Zhenhua Jiang, Lei Jiang   +12 more
doaj   +1 more source

Technicl analysis of a combined juice concentration process involving osmotic evaporation, membrane distillation and direct contact evaporation [PDF]

, 2013
CO2 and water fluxes were measured in membrane distillation and membrane distillation combined with osmotic evaporation. Direct contact evaporation was carried out using water and NaCl solution with the aim of comparing the efficiency of heat exchange ...
Favaro, Enrico
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2004 Office of Fossil Energy Fuel Cell Program Annual Report

, 2004
Annual report of fuel cell projects sponsored by Department of Energy, National Energy Technology ...
National Energy Technology Laboratory (U.S.)
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Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

Advanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li, Zengnan Wu, Yingrui Zhang, Shulang Chen, Yongning Lin, Shiyu Chen, Tong Xu, Xianli Meng, Yi Zhang, Jin‐Ming Lin   +9 more
wiley   +1 more source

A Resource of the National Action Plan for Energy Efficiency [PDF]

, 2009
This brief documents how energy efficiency program administrators have used technical, institutional, financial, and other resources to help advance building energy codes at the federal, state, and local levels, and describes the issues involved in ...
National Action Plan for Energy Efficiency, National Action Plan for Energy Efficiency (U.S.)   +1 more
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Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Effects of matric vs osmotic potential changes on Variovorax beijingensis transcription

mSystems
Soil water potential, which regulates microbe-available water, is controlled by osmotic and matric potential, which both become more negative as soils dry.
Jiwoo Kim, Bjorn Shockey, Kirsten S. Hofmockel, Xiaodong Gao, Caroline A. Masiello, Jonathan J. Silberg   +5 more
doaj   +1 more source

Addendum to A Blueprint for Ocean Energy Development 2010-2015 [PDF]

OWET convened the second annual OWET Developersʼ Summit on August 2, 2011 in Portland, Oregon. The Summit brought together participants, both new and those who had attended the first OWET Developersʼ Summit 2010, to review the Blueprint for Ocean Energy ...
Oregon Wave Energy Trust
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