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European Society for Paediatric Gastroenterology, Hepatology and Nutrition/North American Society for Pediatric Gastroenterology, Hepatology and Nutrition guidelines for treatment of functional constipation in children aged 0-18 years. [PDF]
J Pediatr Gastroenterol NutrGordon M +17 more
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The macrogol revolution in the treatment of chronic constipation. A short history of laxatives. [PDF]
Front PharmacolCorazziari ES.
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Commentary on ‘Osmotic and Stimulant Laxatives for the Management of Childhood Constipation’
Evidence-Based Child Health: A Cochrane Review Journal, 2013AbstractThis is a commentary on a Cochrane review, published in this issue of EBCH, first published as: Gordon M, Naidoo K, Akobeng AK, Thomas AG. Osmotic and stimulant laxatives for the management of childhood constipation. Cochrane Database of Systematic Reviews 2012, Issue 7 Art. No.: CD009118.
Marc A Benninga
exaly +4 more sources
Indian Journal of Gastroenterology, 2022
Pelvic floor dyssynergia (PFD) is one of the causes of chronic constipation. Laxative-based therapies are not very effective in treating this type of constipation. The therapeutic effectiveness of three therapeutic strategies, including biofeedback (BOF) alone, BOF+ fiber laxative (psyllium), and BOF +osmotic laxative (polyethylene glycol; [PEG]), was ...
Saeed Abdi, Habib Malekpour
exaly +3 more sources
Pelvic floor dyssynergia (PFD) is one of the causes of chronic constipation. Laxative-based therapies are not very effective in treating this type of constipation. The therapeutic effectiveness of three therapeutic strategies, including biofeedback (BOF) alone, BOF+ fiber laxative (psyllium), and BOF +osmotic laxative (polyethylene glycol; [PEG]), was ...
Saeed Abdi, Habib Malekpour
exaly +3 more sources
Evidence-Based Child Health: A Cochrane Review Journal, 2013
AbstractBackgroundConstipation within childhood is an extremely common problem. Despite the widespread use of osmotic and stimulant laxatives by health professionals to manage constipation in children, there has been a long standing paucity of high quality evidence to support this practice.ObjectivesWe set out to evaluate the efficacy and safety of ...
Anthony K Akobeng +2 more
exaly +3 more sources
AbstractBackgroundConstipation within childhood is an extremely common problem. Despite the widespread use of osmotic and stimulant laxatives by health professionals to manage constipation in children, there has been a long standing paucity of high quality evidence to support this practice.ObjectivesWe set out to evaluate the efficacy and safety of ...
Anthony K Akobeng +2 more
exaly +3 more sources
Life Sciences, 2011
We have suggested that an osmotic laxative, magnesium sulphate (MgSO(4)), may act as a cathartic in a very rational manner by increasing the aquaporin 3 (AQP3) expression level and by changing osmotic pressure in the colon. In this study, we examined the mechanism by which MgSO(4) increases the intestinal AQP3 expression level by using the human colon ...
Nobutomo Ikarashi +2 more
exaly +3 more sources
We have suggested that an osmotic laxative, magnesium sulphate (MgSO(4)), may act as a cathartic in a very rational manner by increasing the aquaporin 3 (AQP3) expression level and by changing osmotic pressure in the colon. In this study, we examined the mechanism by which MgSO(4) increases the intestinal AQP3 expression level by using the human colon ...
Nobutomo Ikarashi +2 more
exaly +3 more sources
Journal of Gastroenterology and Hepatology (Australia)
ABSTRACTObjectiveThe objective of this study is to compare the efficacy and safety of lubiprostone (Lub) with osmotic laxatives in the treatment of chronic idiopathic constipation (CIC).MethodsA comprehensive literature search was conducted using PubMed, EMBASE, and the Cochrane Library in May 2024. Studies that met the inclusion criteria were manually
Lingye Zhang +2 more
exaly +3 more sources
ABSTRACTObjectiveThe objective of this study is to compare the efficacy and safety of lubiprostone (Lub) with osmotic laxatives in the treatment of chronic idiopathic constipation (CIC).MethodsA comprehensive literature search was conducted using PubMed, EMBASE, and the Cochrane Library in May 2024. Studies that met the inclusion criteria were manually
Lingye Zhang +2 more
exaly +3 more sources
Constipation—Modern Laxative Therapy
Supportive Care in Cancer, 2003 It is estimated that one third of the population in Western industrial countries suffers from constipation at least from time to time. Constipation may have somatopathic or functional causes.
Christoph Ostgathe, E Klaschik, F Nauck
exaly +2 more sources
Advances in Therapy, 2022
Linaclotide, a selective agonist of guanylate cyclase C, was highly recommended for the treatment of irritable bowel syndrome with constipation (IBS-C). However, the cost-effectiveness of linaclotide in Chinese is not known, and this study aimed to assess the cost-effectiveness of linaclotide for patients with IBS-C.An economic evaluation was conducted
Dunming, Xiao +4 more
openaire +2 more sources
Linaclotide, a selective agonist of guanylate cyclase C, was highly recommended for the treatment of irritable bowel syndrome with constipation (IBS-C). However, the cost-effectiveness of linaclotide in Chinese is not known, and this study aimed to assess the cost-effectiveness of linaclotide for patients with IBS-C.An economic evaluation was conducted
Dunming, Xiao +4 more
openaire +2 more sources