Results 51 to 60 of about 82,057 (154)

Pediococcus acidilactici PA53 Supplementation Improves Stool Form and Modulates Gut Microbiota and Inflammatory Responses in Adults With Functional Constipation: A Randomized, Double‐Blind, Placebo‐Controlled Trial

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
In this randomized, double‐blind, placebo‐controlled trial, 8‐week supplementation with Pediococcus acidilactici PA53 significantly improved stool form in adults with functional constipation. PA53 supplementation was associated with changes in inflammatory markers and gut microbiota, including increased Pediococcus abundance.
Yuhan Xia   +5 more
wiley   +1 more source

Modern and promising ways of bowel preparation for instrumental research

open access: yesАмбулаторная хирургия, 2021
A review is presented to summarize data on intestinal preparation approaches and methods for research. The historical background and main stages in the development of the intestinal lavage method are highlighted, and traditional and modern methods of ...
E. V. Kanner   +4 more
doaj   +1 more source

Use of laxatives in institutions for the mentally retarded

open access: yes, 1999
Objective: To study, in institutionalized mentally retarded patients, the prevalence of regular laxative use, and to identify its correlates. Methods: Twenty-one of the 22 institutions for the mentally retarded in Flanders (Belgium) provided the setting ...
De Bacquer, Dirk   +3 more
core   +1 more source

Mechanisms of chronic constipation in children and correction

open access: yesМедицинский совет, 2013
Chronic constipations represent a heterogeneous group of disorders. They may be a manifestation of irritable bowel syndrome, congenital anomalies (Hirschsprung's disease), or they may be functional, further subdivided into normal or slow transit.
E. A. Kornienko
doaj   +1 more source

Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent Klebsiella pneumoniae

open access: yesiMeta, Volume 5, Issue 5, October 2026.
Transient exposure to ampicillin results in restructuring of microbiota to favor oxygen‐tolerant bacteria, whereas osmotic laxative perturbation preserves Bacteriodota. Ampicillin‐ but not laxative‐exposed environment favors establishment of rmpA phase variants that lost hypermucoviscosity but short‐chain fatty acids present in the laxative‐exposed gut
Carey Lim   +9 more
wiley   +1 more source

Use of over-the-counter laxatives by community-dwelling adults to treat and prevent constipation: a national cross-sectional study.

open access: yes, 2020
PURPOSE:Constipation is commonly self-managed with over-the-counter laxatives. The study aim was to explore laxative choice, healthcare professional recommendations in laxative selection, and laxative effectiveness when laxatives are used for treatment ...
Williams, KA   +3 more
core   +1 more source

Chronic Constipation: Current Treatment Options

open access: yesCanadian Journal of Gastroenterology, 2011
Chronic constipation is a common functional gastrointestinal disorder that affects patients of all ages. In 2007, a consensus group of 10 Canadian gastroenterologists developed a set of recommendations pertaining to the management of chronic constipation
Louis Wing Cheong Liu
doaj   +1 more source

Gastrointestinal adverse effects of GLP‐1 receptor agonists and dual GIP/GLP‐1 receptor agonists: A narrative expert review of approved therapies, oral formulations, and pipeline agents

open access: yesNutrition in Clinical Practice, Volume 41, Issue 5, Page 1318-1333, October 2026.
Abstract Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1 receptor agonists have transformed the management of type 2 diabetes and obesity. Gastrointestinal (GI) adverse events are the most common limitation of these therapies and a leading cause of discontinuation ...
Vikash Singhani   +6 more
wiley   +1 more source

Edible Rose and Roselle: A Critical Review of Nutritional Composition, Safety, and Regulatory Considerations for Product Development

open access: yesJournal of Food Science, Volume 91, Issue 10, October 2026.
ABSTRACT The growing demand for sustainable and health‐promoting products has increased scientific and industrial interest in edible flowers as functional ingredients. Rose (Rosa spp.) and roselle (Hibiscus sabdariffa L.) have gained attention for their traditional use, diverse phytochemical composition, and emerging applications in functional foods ...
Temilola Dada   +2 more
wiley   +1 more source

Tenapanor Beyond Phosphate: Gut Sodium Transport, Stool Transit Time, and Volume Balance in Dialysis Patients

open access: yesHemodialysis International, Volume 30, Issue 4, Page 689-697, October 2026.
ABSTRACT Introduction Tenapanor, a minimally absorbed intestinal NHE3 inhibitor approved for hyperphosphatemia in dialysis, lowers phosphate and reduces intestinal sodium absorption. Its sodium–water signal may have implications beyond phosphate but remains poorly separated from diarrhea‐mediated losses and dialysis prescription artifacts. Methods This
Lucas Maciel de Almeida Corrêa   +8 more
wiley   +1 more source

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