Augmentation With Pre-Emptive Macrogol-Based Osmotic Laxative Does Not Significantly Improve Standard Bowel Preparation in Unselected Patients: A Randomized Trial [PDF]
Background and Aim The addition of a laxative prior to a standard bowel preparation (BP) has shown variable results in efficacy, safety, and tolerability of the BP.
Jeremy Dwyer, Shara N Ket, John Reynolds
exaly +5 more sources
Osmotic Laxative Versus Stimulant Laxative in the Management of Childhood Functional Constipation
Background and objectives: Constipation within children is an extremely common problem. The objective of this study is to evaluate and compare the efficacy and safety of osmotic and stimulant laxative used to treat functional constipation in children.
Areen Sarteep Fattah +1 more
exaly +5 more sources
An Osmotic Laxative Renders Mice Susceptible to Prolonged Clostridioides difficile Colonization and Hinders Clearance [PDF]
Diarrheal samples from patients taking laxatives are typically rejected for Clostridioides difficileC ...
Sarah Tomkovich +9 more
doaj +4 more sources
Aim: The purpose of the study was to evaluate the efficiency of using the osmotic laxative polyethyleneglycol 4000 (PEG) for treatment of constipation in children.
S. I. Erdes, B. O. Matsukatova
doaj +4 more sources
Efficacy of osmotic laxative polyethylene glycol 4000 in treatment of constipation in pediatrics
Aim of investigation. To evaluate the dynamics of clinical symptoms of constipation at children and parameters of peripheral electrogastroenterography (PEGEG) on treatment with osmotic laxative polyethylene glycol 4000 (PEGs).Material and methods.
S. I. Erdes +3 more
doaj +2 more sources
Patients with severe constipation are treated with combinations of several different laxatives. The purpose of this study is to examine whether the concomitant use of different laxatives enhances the laxative effect, using an osmotic laxative, magnesium sulphate (MgSO₄), and a stimulant laxative, bisacodyl.
Kiyoshi Sugiyama +2 more
exaly +3 more sources
Impact of STIMUlant and Osmotic LAXatives (STIMULAX Trial) on Gastrointestinal Recovery After Colorectal Surgery: Randomized Clinical Trial. [PDF]
Abstract Background Recovery of gastrointestinal (GI) function is often delayed after colorectal surgery. Enhanced recovery protocols (ERPs) recommend routine laxative use, but evidence of benefit is unclear. This study aimed to investigate whether the addition of multimodal laxatives to an ERP
Sergei Bedrikovetski +2 more
exaly +4 more sources
Aim: to assess clinical efficacy of polietilenglicol (macrogol) with molecular weight 4000 kDa in children with chronic constipation. Patients and methods: clinical efficacy was assessed in 30 children aged 2–12 years with chronic constipation.
A. V. Eremeeva
doaj +3 more sources
Prunus domestica as effective and acceptable treatment for stool softening and relief of constipation symptoms [PDF]
Constipation, a worldwide gastrointestinal disorder needs to osmotic and stimulant laxatives. The use of herbal medicines as laxative agents is prevalent in folk and traditional medicines. Prunus L. and especially P.
Mohaddese Mahboubi
doaj +1 more source
BackgroundLaxatives are among the most commonly used pharmacological agents worldwide. Available data indicate a significant potential for clinically relevant drug-drug interactions. We hypothesized that osmotic laxatives may reduce the oral bioavailability of the direct oral anticoagulant dabigatran and thereby its anticoagulant effects.MethodsIn the ...
Bernd Jilma +2 more
exaly +4 more sources

