Results 121 to 130 of about 117,397 (279)

Oral osmotic pump drug delivery systems: A narrative review of structural designs, functional mechanisms and emerging applications

Pakistan Journal of Pharmaceutical Sciences
Traditional oral formulations often lead to significant fluctuations in plasma drug concentrations. In contrast, oral osmotic pumps achieve zero-order drug release driven by osmotic pressure, which is largely independent of physiological variables ...
Xintao Qiu, Jing Shu, Yuanyuan Chen, Qing Min, Yuting Bai, Hui Yao, Shuanglin Qin   +6 more
doaj   +1 more source

Wheat can acclimate to seawater by pretreatment with kinetin and spermine through osmotic adjustment and solutes allocation [PDF]

Journal of Stress Physiology & Biochemistry, 2013
A key issue in salt adaptation is the osmotic adjustment, therefore, during ear emergence the effect of exogenous application of kinetin and spermine on osmotic pressure (OP) and solutes allocation (total soluble sugars, total soluble nitrogen, proline ...
Heshmat S. Aldesuquy, Zakaria A. Baka, Berdees M. Mickky   +2 more
doaj  

The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton

Advanced Science, EarlyView.
Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang, Jie Dai, Ting Zhao, Shengjun Zhao, Hongyu Wu, Jiaying Pan, Yupeng Hao, Ke Nie, Li Yu, Yumeng Zhu, Xiangyi Zhao, Kai Huang, Mengke Zhang, Yongyan Zhao, Yaping Jiang, Siyuan Wang, Yiling Pan, Yubing Chen, Yilai Lin, Wanghong Shi, Yayuan Deng, Jin Han, Jie Li, Xuan Long, Junbin Wang, Zhiyuan Zhang, Zegang Han, Zhanfeng Si, Lei Ju, Jun Li, Tianzhen Zhang, Ji Zhou, Xueying Guan   +32 more
wiley   +1 more source

Response of heterologously expressed pressure sensor-actuator-modulator macromolecule to external mechanical stress

Heliyon
Cells from different organs in the body experience a range of mechanical and osmotic pressures that change in various diseases, including neurological, cardiovascular, ophthalmological, and renal diseases.
Subrata Batabyal, Chinenye Idigo, Darryl Narcisse, Adnan Dibas, Samarendra Mohanty   +4 more
doaj   +1 more source

T2T Genome Assembly and Multi‐Omics Data Reveal Terrestrial Adaptation and Mucus Biosynthesis in Tropical Leatherleaf Slug (Laevicaulis alte)

Advanced Science, EarlyView.
A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang, Shaofang He, Zhongkai Wang, Aobo Pang, Xiaoli Sun, Rongchen Liu, Fang Wang, Sisi Chen, Zhijuan Bian, Dongcheng Wei, Liuhan Wu, Siyao Zhao, Qiuting Ji, Yiqi Sun, Niying Sun, Yushinta Fujaya, Boping Tang, Kianann Tan, Daizhen Zhang, Lianfu Chen   +19 more
wiley   +1 more source

Dual Regulation of Ionic Effect on Zostera marina L. Seed Germination and Leaf Differentiation in Low-Salinity Conditions

Plants
Low-salinity conditions are generally used in land-based cultivation to promote the germination and growth of Zostera marina L. and to improve the restoration effect of seagrass beds.
Peilong Li, Yaping Gao, Zengjie Jiang, Linjie Wang, Xiaoli Sun, Jiaqi Wang, Jing Wang, Haidong Sui, Junwei Wang, Yitao Zhang   +9 more
doaj   +1 more source

The osmotic pressure of globin [PDF]

Biochemical Journal, 1932
J, Roche, A, Roche, G S, Adair, M E, Adair   +3 more
openaire   +2 more sources

Targeting the HSPA8‐CMA‐ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer

Advanced Science, EarlyView.
Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An, Ze Gao, Shuo Chen, Liwei Meng, Chen Zhang, Kefan Song, Haochen Cui, Lei Yan, Zhiqing Fang   +8 more
wiley   +1 more source

Water relations of cucumber, tomato, and sweet pepper [PDF]

, 1977
The ever increasing importance of water as a critical resource for agricultural production has encouraged more research on water relations in recent years.
Behboudian, M.H.
core  

Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

Advanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li, Zengnan Wu, Yingrui Zhang, Shulang Chen, Yongning Lin, Shiyu Chen, Tong Xu, Xianli Meng, Yi Zhang, Jin‐Ming Lin   +9 more
wiley   +1 more source