Results 51 to 60 of about 270,818 (335)

Osmotic Stress Induced Cell Death in Wheat Is Alleviated by Tauroursodeoxycholic Acid and Involves Endoplasmic Reticulum Stress–Related Gene Expression

Frontiers in Plant Science, 2017
Although, tauroursodeoxycholic acid (TUDCA) has been widely studied in mammalian cells because of its role in inhibiting apoptosis, its effects on plants remain almost unknown, especially in the case of crops such as wheat.
Liting Zhang, Liting Zhang, Liting Zhang, Zeyu Xin, Zeyu Xin, Zeyu Xin, Xing Yu, Xing Yu, Xing Yu, Chao Ma, Weiwei Liang, Weiwei Liang, Weiwei Liang, Meichen Zhu, Meichen Zhu, Meichen Zhu, Qiwei Cheng, Qiwei Cheng, Qiwei Cheng, Zongzhen Li, Zongzhen Li, Zongzhen Li, Yanan Niu, Yongzhe Ren, Yongzhe Ren, Yongzhe Ren, Zhiqiang Wang, Zhiqiang Wang, Zhiqiang Wang, Tongbao Lin, Tongbao Lin, Tongbao Lin   +31 more
doaj   +1 more source

GPR35 prevents osmotic stress induced cell damage. [PDF]

Commun Biol
Abstract GPR35 is an orphan G-protein coupled receptor that has been implicated in the development of cancer. GPR35 regulates the Na+/K+-ATPase’s pump and signalling function. Here we show GPR35’s critical role in ion flux that in turn controls cellular osmotic pressure and Na+-dependent transport in HepG2 and SW480 cells.
Elias JE, Debela M, Sewell GW, Stopforth RJ, Partl H, Heissbauer S, Holland LM, Karlsen TH, Kaser A, Kaneider NC.   +9 more
europepmc   +4 more sources

Stress-structure relation in dense colloidal melt under forward and instantaneous reversal of shear

, 2015
Dense supercooled colloidal melt in forward shear from a quiescent state shows overshoot in shear stress at 10% strain with an unchanged fluid structure at equal stress before and after overshoot.
Bhattacharjee, Amit Kumar
core   +1 more source

TRPV4 Contributes to Resting Membrane Potential in Retinal Müller Cells: Implications in Cell Volume Regulation [PDF]

, 2017
Neural activity alters osmotic gradients favoring cell swelling in retinal Müller cells. This swelling is followed by a regulatory volume decrease (RVD), partially mediated by an efflux of KCl and water. The transient receptor potential channel 4 (TRPV4),
Capurro, Claudia Graciela, Di Giusto, Gisela, Fernández, Juan, Ford, Paula, Kalstein, Maia, Netti, Vanina Alejandra, Pizzoni, Alejandro, Rivarola, Valeria   +7 more
core   +1 more source

From START to FINISH : the influence of osmotic stress on the cell cycle [PDF]

, 2013
Peer reviewedPublisher ...
A Amon, A Bardin, A Ciliberto, A Goldbeter, A Skirycz, Alistair J. P. Brown, C Dahmann, C Epstein, Celso Grebogi, CL Theesfeld, D Lew, D Lew, D McCollum, D Morgan, Despoina Kaloriti, DJ Lew, E Nigg, E Schwob, E Schwob, E Traverso, Elahe Radmaneshfar, F Cross, F Cross, F Stegmeier, F Stegmeier, G Bellí, G Yaakov, H Claeys, H Saito, J Brewster, J Clotet, J McMillan, JL Burton, K Chen, K Chen, KJ Simpson-Lavy, L Dirick, M Adrover, M Alexander, M Barberis, M Barberis, M Barberis, M Gustin, M Mendenhall, M Tyers, M. Carmen Romano, Marco Thiel, Michael C. Gustin, Michael Polymenis, N Grandin, Neil A. R. Gow, P Nash, P Nurse, R Sia, R Sia, R Venta, R Verma, RN Booher, S Chandrasekaran, S Ghaemmaghami, S Jaspersen, S Jensen, S Piatti, T Su, U Surana, V Nguyen, V Reiser, W Zachariae, X Escoté, Z Zi   +69 more
core   +3 more sources

Measuring the force ejecting DNA from phage [PDF]

, 2004
We discuss how a balance can be established between the force acting to eject DNA from viral capsids and the force resisting its entry into a colloidal suspension which mimics the host cell cytoplasm.
Castelnovo, M., Evilevitch, A., Gelbart, W. M., Knobler, C. M.   +3 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Effect of salt and sugar osmotic stress on the viability and morphology of Saccharomyces boulardii [PDF]

, 2016
Changes in the viability, composition and morphology of the probiotic yeast Saccharomyces boulardiiwerefollowed inhyperosmoticYPD broths withNaCland sucrosein concentration ranges from0.2 to 2M. Samples were observedbyscanning (SEM) and transmission (TEM)
Acosta-Garcia, M. C. (M), Avila-Reyes, S. V. (S), Camacho-Diaz, B. H. (B), Hernandez-Sanchez, H. (H), Jimenez-Aparicio, A. R. (A)   +4 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Maize multi-omics reveal leaf water status controlling of differential transcriptomes, proteomes and hormones as mechanisms of age-dependent osmotic stress response in leaves

Stress Biology
Drought-induced osmotic stress severely affects the growth and yield of maize. However, the mechanisms underlying the different responses of young and old maize leaves to osmotic stress remain unclear.
Liangjie Niu, Wenkang Wang, Yingxue Li, Xiaolin Wu, Wei Wang   +4 more
doaj   +1 more source