Results 51 to 60 of about 39,993 (353)

Intra-Articular Injection in Wistar Rats: Standardization and Experimental Validation of a Precise Protocol for Nanomaterial Administration

Nanomaterials
(1) Background: Intra-articular injection is a fundamental technique in preclinical research for evaluating therapeutics and inducing joint disease models in rodents.
Manuel Flores-Sáenz, Belén Chico, Maria C. García Alonso, Celia Clemente de Arriba, Soledad Aguado-Henche   +4 more
doaj   +1 more source

OsteoMacs and Their Role in Early Implant Failure and Osseointegration.

, 2022
Dental implant failure cannot always be explained by clinical risk factors. Recent literature suggests that immune cells are pivotal players in the integration of biomaterials and have a co-relationship within a set of osteal macrophages known as ...
Talib, Huzefa S, Yang, Richard M, Wiedemann, Thomas G, Miron, Richard J   +3 more
core  

Bamboo‐Like Whiskers‐Reinforced Bioceramics Accelerate Large Segmental Bone Regeneration via Dual Modulation of Type‐H Vessels and Osteoinduction

Advanced Science, EarlyView.
The graphical abstract image of bamboo‐like whisker‐reinforced Ca‐P bioceramics accelerating large segmental bone regeneration. ABSTRACT Regenerative repair of segmental bone defect remains a major clinical challenge. The conventional mental implants suffer from mechanical strength mismatch and long‐term foreign bodies presence.
Cong Feng, Haibo Teng, Chuyao Xu, Jiaze He, Keting Liu, Xueying Li, Kai Zhang, Xiangdong Zhu, Xiangfeng Li, Jianguo Xu, Xingdong Zhang   +10 more
wiley   +1 more source

An in vivo evaluation of bone response to three implant surfaces using a rabbit intramedullary rod model

Journal of Orthopaedic Surgery and Research, 2010
Our study was designed to evaluate osseointegration among implants with three surface treatments: plasma-sprayed titanium (P), plasma-sprayed titanium with hydroxyapatite (PHA), and chemical-textured titanium with hydroxyapatite (CHA).
Hermida Juan C, Bergula Arnie, Dimaano Fred, Hawkins Monica, Colwell Clifford W, D'Lima Darryl D   +5 more
doaj   +1 more source

In Vitro and In Vivo Studies of Hydrogenated Titanium Dioxide Nanotubes with Superhydrophilic Surfaces during Early Osseointegration

Cells, 2022
Titanium-based implants are often utilized in oral implantology and craniofacial reconstructions. However, the biological inertness of machined titanium commonly results in unsatisfactory osseointegration.
Caiyun Wang, Shang Gao, Ran Lu, Xin Wang, Su Chen   +4 more
doaj   +1 more source

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

Advanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun, Bo Jia, Jiahui Shi, Shuang Li, Guo Bao, Dong Bian, Kai Chen, Junlong Tan, Xuenan Gu, Yan Guan, Yu Qin, Xinhua Qu, Xiaogang Wang, Yufeng Zheng, Hongtao Yang   +14 more
wiley   +1 more source

Breaking Barriers—The Promise and Challenges of Limb Osseointegration Surgery

Medicina
Limb amputation remains a significant global health issue, affecting millions of individuals annually. A substantial proportion of these patients struggle with the inadequate fit and discomfort of conventional prosthetic sockets, leading to diminished ...
Agnieszka Wnuk-Scardaccione, Jan Bilski
doaj   +1 more source

RADIOGRAPHIC EVALUATION OF OSSEOINTEGRATION OF UNCEMENTED TARGOS® STEMS. A 5-YEAR FOLLOW-UP

Acta Ortopédica Brasileira, 2022
Introduction Total hip arthroplasty is a widespread treatment and is considered the gold standard in cases of hip osteoarthritis, with high rates of success in improving pain and function when well performed.
Helder de Souza Miyahara, Jorge Henrique Narciso, José Guilherme Lollo Correa, José Ricardo Negreiros Vicente, Leandro Ejnisman, Bruno Alves Rudelli, Henrique de Melo Campos Gurgel, Alberto Tesconi Croci   +7 more
doaj   +1 more source

Nanodiamonds as Bioactive Platforms to Modulate Microbial, Mammalian, and Vertebrate Systems

Advanced NanoBiomed Research, EarlyView.
Nanodiamonds (NDs) are biocompatible and antibacterial nanomaterials that support mammalian cell growth while inhibiting bacterial pathogens. NDs showed strong antibacterial activity, with Escherichia coli being more sensitive than Staphylococcus aureus. At 10 mg/mL, both bacteria exhibited ~8% viability.
Aaqil Rifai, Ayushi Priyam, Ahmed Rashed, Gebreselassie Addisu Tilaye, Kamal Poudel, Aaron G. Schultz, Richard J. Williams   +6 more
wiley   +1 more source

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

Advanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei, Yogambha Ramaswamy, Young Jung No   +2 more
wiley   +1 more source