Results 11 to 20 of about 73,277 (253)

Heterotopic Ossification: Clinical Features, Basic Researches, and Mechanical Stimulations

Frontiers in Cell and Developmental Biology, 2022
Heterotopic ossification (HO) is defined as the occurrence of extraskeletal bone in soft tissue. Although this pathological osteogenesis process involves the participation of osteoblasts and osteoclasts during the formation of bone structures, it differs
Yili Xu, Mei Huang, Wenzhen He, Chen He, Kaixuan Chen, Jing Hou, Min Huang, Yurui Jiao, Ran Liu, Nanyu Zou, Ling Liu, Changjun Li, Changjun Li, Changjun Li   +13 more
doaj   +2 more sources

Use of Acellular Dermal Matrix to Prevent Recurrence of Radioulnar Heterotopic Ossification [PDF]

Plastic and Reconstructive Surgery, Global Open, 2019
Summary:. Radioulnar heterotopic ossification is a rare occurrence found in approximately 2% of all forearm injuries. Treatment is complicated by relatively high recurrence rates.
Daniel J. Gould, MD, PhD, Paymon Rahgozar, MD, Eric S. Nagengast, MD, David A. Kulber, MD   +3 more
doaj   +3 more sources

Heterotopic ossification after patellar tendon repair in a man with trisomy 8 mosaicism: a case report and literature review [PDF]

Journal of Medical Case Reports, 2011
Introduction Heterotopic ossification is the abnormal formation of lamellar bone in soft tissue. Its presence jeopardizes functional outcome, impairs rehabilitation and increases costs due to subsequent surgical interventions.
Chmell Samuel, Chen Austin
doaj   +4 more sources

Heterotopic mesenteric ossification in a child: Case report [PDF]

Iatreia, 2016
The term heterotopic ossification refers to bone formation in normally non-ossifying tissue. It represents a benign, localized, self-limiting and well-circumscribed lesion, and the phenomenon is rather unusual in the immediate vicinity of bones. Likewise,
Herrera-Toro, Natalia, Mejía-Sarasti, Francisco Javier   +1 more
doaj   +5 more sources

Pulmonary Adenocarcinoma with Heterotopic Ossification [PDF]

Journal of Korean Medical Science, 2009
Pulmonary adenocarcinoma is a common malignancy that often involves calcification; however, bone formation in primary lung adenocarcinoma is extremely rare. In ten cases of primary pulmonary adenocarcinoma with heterotopic ossification, we detected immunoreactivity against TGF-beta1, osteopontin, osteocalcin and Runx2 in the fibroblastic stroma and ...
Jhingook Kim, Gou Young Kim, Tae Sung Kim, Joungho Han   +3 more
openaire   +5 more sources

Verteporfin attenuates trauma‐induced heterotopic ossification of Achilles tendon by inhibiting osteogenesis and angiogenesis involving YAP/β‐catenin signaling

The FASEB Journal, 2023
Heterotopic ossification occurs as a pathological ossification condition characterized by ectopic bone formation within soft tissues following trauma. Vascularization has long been established to fuel skeletal ossification during tissue development and ...
Gang Luo, Ziyang Sun, Hang Liu, Zheng Yuan, Wei Wang, B. Tu, Juehong Li, C. Fan   +7 more
semanticscholar   +1 more source

Fibrodysplasia ossificans progressiva: A rare disease with spinal deformity and severe hip dysfunction

Frontiers in Pediatrics, 2022
IntroductionProgressive fibrous dysplasia ossification (FOP) is a rare genetic disease characterized by congenital bone malformations and soft tissue masses that progress to heterotopic ossification.
Dong Sun, Peng Liu, Zhaolin Wang, Jianhu Mu, Jian Cao   +4 more
doaj   +1 more source

Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery

Nature Communications, 2022
Heterotopic ossification is the most disabling feature of fibrodysplasia ossificans progressiva, an ultra-rare genetic disorder for which there is currently no prevention or treatment.
Yeon-Suk Yang, Jung-Min Kim, Jun Xie, Sachin Chaugule, Chujiao Lin, Hong Ma, E. Hsiao, Jaehyoung Hong, H. Chun, E. Shore, F. Kaplan, Guangping Gao, Jae-Hyuck Shim   +12 more
semanticscholar   +1 more source

A self-amplifying loop of YAP and SHH drives formation and expansion of heterotopic ossification

Science Translational Medicine, 2021
A self-amplifying and propagating loop of YAP-SHH is a core molecular mechanism underlying diverse forms of heterotopic ossification. Understanding heterotopic ossification Heterotopic ossification (HO), a condition where bone forms in nonskeletal ...
Qian Cong, Yuchen Liu, Taifeng Zhou, Yaxing Zhou, R. Xu, Caiqi Cheng, Hye Soo Chung, Mei-Jun Yan, Hang Zhou, Zhiheng Liao, Bo Gao, G. Bocobo, T. Covington, Hyeon Ju Song, Peiqiang Su, P. Yu, Yingzi Yang   +16 more
semanticscholar   +1 more source

Impact of Heterotopic Ossification on Functional Recovery in Acute Spinal Cord Injury

Frontiers in Cellular Neuroscience, 2022
Objective: In spinal cord injury (SCI), heterotopic ossification is a frequent secondary complication, commonly associated with limited range of motion of affected joints, which could lead to secondary disability in activities of daily living ...
Steffen Franz, Lukas Rust, Laura Heutehaus, Rüdiger Rupp, Christian Schuld, Norbert Weidner   +5 more
doaj   +1 more source