Results 61 to 70 of about 41,789 (173)

Cumulative effects of lifelong systemic excess growth hormone on postcranial skeletal morphology in adult mice

Journal of Anatomy, EarlyView.
Our μCT‐based pilot study reveals size and shape disparity in the adult postcranial skeleton of growth‐hormone model (bGH) mice relative to wild‐type mice. bGH mice have larger and more sexually dimorphic bones, with a systemic radiodensity increase in bony sesamoids and associated, but typically uncalcified, soft tissues.
Joseph R. Groenke, Huanhuan Liu, Grace Lach, Abhishek Wajpe, Darlene Berryman, John J. Kopchick, Shouan Zhu, Patrick M. O'Connor   +7 more
wiley   +1 more source

Heterotopic Ossification After an Achilles Tendon Rupture Cannot Be Prevented by Early Functional Rehabilitation: A Cohort Study

, 2020
Background Tendon loading might play a role in the development of heterotopic ossification after Achilles tendon ruptures. Early heavy loading on a healing tendon in animals has been shown to prolong the proinflammatory response, and inflammatory cells ...
Couppe, Christian, Eliasson, Pernilla T.,, Svensson, Rene B., Pernilla Eliasson, René B. Svensson, Agergaard, Anne-Sofie,, Magnusson, S. Peter,, Susan Warming, Anne-Sofie Agergaard, S. Peter Magnusson, Eliasson, Pernilla, Michael R. Krogsgaard, Warming, Susan,, Couppe, Christian,, Krogsgaard, Michael R., Svensson, Rene B.,, Magnusson, S. Peter, Eliasson, Pernilla T., Kjaer, Michael,, Michael Kjaer, Kjaer, Michael, Krogsgaard, Michael R.,, Christian Couppé, Warming, Susan, Agergaard, Anne Sofie, Agergaard, Anne-Sofie   +25 more
core   +1 more source

Effect of Keeping Caspar Retractor During Prestige LP Cervical Disc Implantation on Intra‐ and Postoperative Outcomes

Orthopaedic Surgery, EarlyView.
This study evaluated the effect of retaining the Caspar retractor during Prestige LP implantation in cervical disc arthroplasty (CDA). Although the manufacturer recommends removal, removal caused vertebral instability during endplate drilling/cutting. Retaining the retractor reduced angle fluctuations, implantation time, and fluoroscopy usage, though ...
Xiaoqiang Zhao, Xiao Yang, Minghe Yao, Kangkang Huang, Tingkui Wu, Shihao Chen, Yi Deng, Hao Liu, Beiyu Wang   +8 more
wiley   +1 more source

An unusual complication after syndesmotic injury: retrotibial heterotopic ossification

, 2009
A 27-year-old male patient sustained an isolated syndesmotic injury in the right ankle following a fall. His complaints subsided gradually within the first six weeks of conservative treatment.
Akman, Senol, Uludag, Serkan, Seyahi, Aksel, Demirhan, Mehmet   +3 more
core   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Clinical Aspects and Current Therapeutic Approaches for FOP

Biomedicines, 2020
Fibrodysplasia ossificans progressiva (FOP) is an extremely rare heritable disorder of connective tissues characterized by progressive heterotopic ossification in various skeletal sites.
Hiroshi Kitoh
doaj   +1 more source

A Systematic Review of Complications Following Elective Foot and Ankle Surgery

Journal of Foot and Ankle Research, Volume 19, Issue 4, December 2026.
ABSTRACT Introduction Complications following elective foot and ankle surgery are a significant source of morbidity and may impair recovery. Evidence is often procedure specific, limiting a broader understanding. This review aimed to synthesize complication profiles, risk factors, and mitigation strategies across elective procedures.
Lia Spencer, Connor Phillips, Sifat Alam, Kit Ferguson, Richard Feinn, Douglas McHugh, Ewan Kannegieter   +6 more
wiley   +1 more source

Interorgan communication in neurogenic heterotopic ossification: the role of brain-derived extracellular vesicles

Bone Research
Brain-derived extracellular vesicles participate in interorgan communication after traumatic brain injury by transporting pathogens to initiate secondary injury. Inflammasome-related proteins encapsulated in brain-derived extracellular vesicles can cross
Weicheng Lu, Jianfei Yan, Chenyu Wang, Wenpin Qin, Xiaoxiao Han, Zixuan Qin, Yu Wei, Haoqing Xu, Jialu Gao, Changhe Gao, Tao Ye, Franklin R. Tay, Lina Niu, Kai Jiao   +13 more
doaj   +1 more source

Nerve Growth Factor is Sufficient to Cause Multiple Osteoarthritis‐Relevant Pathologic Features in Naïve Murine Knee Joints

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2246-2260, November 2026.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped because of side effects in the joints. Knowledge about the biologic effects of NGF on joint tissues is limited. Therefore, we explored the effects
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Wound breakdown reconstructed by reverse lateral arm flap after excision of heterotopic ossification of the elbow following severe burn injury: A case report

Burns Open, 2017
We report the case of a wound complication that was reconstructed by reverse lateral arm flap after excision of heterotopic ossification (HO) of the elbow in a patient with severe burns.
Akihiro Hirakawa, Yoshiyuki Ohno, Shingo Komura, Haruhiko Akiyama   +3 more
doaj   +1 more source