Results 61 to 70 of about 3,319 (171)

Brown Tumors Mimicking Skeletal Metastases: A Diagnostic Pitfall in Primary Hyperparathyroidism. [PDF]

Clin Case Rep
ABSTRACT Brown tumors are rare but important manifestations of primary hyperparathyroidism (PHPT). These benign, fibrotic, and erosive bony lesions result from localized rapid osteoclastic activity driven by excessive parathyroid hormone levels. Although brown tumors are considered one of the most pathognomonic signs of PHPT, they are infrequently ...
Akbar U, Ahmad O, Sajjad F, Saeed K, Dawar U, Shah MS, Afridi A, Kamil KA.   +7 more
europepmc   +2 more sources

Unusual body weight loss due to primary hyperparathyroidism: A case study with literature review

Heliyon
Brown tumors (osteitis fibrosa cystica) are rare pathognomonic signs that occur in patients with primary hyperparathyroidism (PHPT). Brown tumors can exist in multiple bones and can easily be misdiagnosed as a metastatic tumor or multiple myeloma.
Yan-Yu Lin, Shuen-Fu Weng, Ting-Teng Yang, Yi-Wei Lee, Ju-Han Liu, Yu-Shan Hsieh   +5 more
doaj   +1 more source

A 60-year-old man with chronic renal failure and a costal mass: a case report and review of the literature

Journal of Medical Case Reports, 2009
Introduction Brown tumors are a rare focal manifestation of osteitis fibrosa cystica, which results from hyperparathyroidism. Chronic kidney failure may lead to secondary or tertiary hyperparathyroidism and thus to osteitis fibrosa cystica and brown ...
Campuzano-Zuluaga Germán, Velasco-Pérez William, Marín-Zuluaga Juan Ignacio   +2 more
doaj   +1 more source

Multiple brown tumors—Forgotten pathology in times of calcimimetics: A case report and literature review

SAGE Open Medical Case Reports, 2021
Multiple brown tumors represent a rare variant of osteitis fibrosa cystica. Brown tumors are associated with primary, secondary, or tertiary hyperparathyroidism. Brown tumors have been reported in patients with chronic kidney disease resulting in mineral
José Carlos De La Flor Merino, Pablo Justo, Juan J. Domínguez, Ana Gómez-Berrocal, Antonio E. Seva, Alexander Marschall, Miguel Rodeles   +6 more
doaj   +1 more source

Multiple bone fractures with a hidden aetiology-A case report

Journal of Pathology of Nepal, 2022
A patient presented with fracture of multiple bones, on investigations, showed primary hyperparathyroidism due to an adenoma in the inferior parathyroid gland. The bones showed typical changes of hyperparathyroidism in the form of osteitis fibrosa.
P. Sankaran Jayalakshmy, Sreelekshmi K. Thunoli, Asiq N. Siddeeque   +2 more
doaj   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

LONG-LASTING ADVANCED PRIMARY HYPERPARATHYROIDISM ASSOCIETED WITH END-STAGE RENAL FAILURE IN A DIABETIC PATIENT [PDF]

Acta Medica Iranica, 2004
In this report we explain a case of primary hyperparathyroidism in a 45 years old diabetic woman that was initially presented with recurrent nephrolithiasis of more than 10 years duration leading to right complete and left partial nephrectomy and ...
H. Nasri A. Baradaran
doaj   +1 more source

Primary Hyperparathyroidism With Brown Tumor—A Case Mistaken as Non‐Ossifying Fibroma Resolved by Biochemical and Radiological Correlation

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Primary hyperparathyroidism (PHPT) is uncommon in the pediatric population and rarely presents with overt skeletal complications such as brown tumors. This case study describes a 16‐year‐old female who initially presented with abdominal pain and was subsequently found to have severe hypercalcemia (serum calcium 16.4 mg/dL) and markedly ...
Dosti Regmi, Uma Bhatta, Madhur Bhattarai, Saurav Jha, Akriti Baral   +4 more
wiley   +1 more source

Management of adynamic bone disease in chronic kidney disease: A brief review

Journal of Clinical & Translational Endocrinology, 2016
The Kidney Disease: Improving Global Outcomes (KDIGO) work group released recommendations in 2006 to define the bone-related pathology associated with chronic kidney disease as renal osteodystrophy.
Swathi K. Sista, Seth M. Arum
doaj   +1 more source

Severe Hypercalcemia and Confusion in a Middle‐Aged Male: The Hidden Diagnosis of Parathyroid Carcinoma

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Parathyroid cancer (PC) is one of the rarest causes of primary hyperparathyroidism (PHPT), typically exhibiting an indolent course but presenting with more severe symptoms compared to its benign counterparts. The diagnosis is most often made postoperatively through histopathological examination; however, certain clinical and biochemical features may ...
Helena Fahmi, Mahmoud Karaki, Fatima Yasmin, Layal Akl, Paola Atallah, Osamu Isozaki   +5 more
wiley   +1 more source