Results 91 to 100 of about 131,552 (309)

Hip osteoarthritis – histopathological aspects

Romanian Journal of Morphology and Embryology
Osteoarthritis is a complex, degenerative disease that can affect all the anatomical structures of the synovial joints. Most frequently, the joints of the hand, hip, and knee are affected, especially in the elderly patients. In our study, we evaluated 27 femoral heads, examining the histopathological changes that occurred in the articular cartilage ...
Paraliov, Anton Tiberiu, Vicaş, Răzvan Marius, Dîrnu, Rodica, Guţă, Natalia, Radu, Lucreţiu, Mogoantă, Laurenţiu, Nicolescu, Laura-Corina   +6 more
openaire   +2 more sources

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova, Alexis Klee, Mina Botros, Victoria L. Hansen, John Reuter, Eliya Tazreena Tashbib, Eloise Fadial, Benjamin F. Ricciardi, Brian Giordano, Chia‐Lung Wu   +9 more
wiley   +1 more source

The Natural History of Femoroacetabular Impingement

Frontiers in Surgery, 2015
Femoroacetabular impingement (FAI) is a clinical syndrome resulting from abnormal hip joint morphology and is a common cause of hip pain in young adults.
Benjamin D. Kuhns, Alexander E. Weber, David M. Levy, Thomas H. Wuerz   +3 more
doaj   +1 more source

Is hip osteoarthritis preventable?

Joint Bone Spine, 2020
Abstract One quarter of 45-year-old adults will develop symptomatic hip osteoarthritis (OA). Therefore, hip OA affects a very significant number of patients and, together with knee OA, is associated with increased cardiovascular mortality. Primary prevention involves the identification and management of its modifiable risk factors. Those that we know
Alice, Courties, Francis, Berenbaum
openaire   +3 more sources

Visual Hypersensitivity as a Transdiagnostic Marker of Surgical Pain Response in Arthritis and Chronic Pain Syndromes

Arthritis &Rheumatology, EarlyView.
Objective Nociplastic pain is pain primarily driven by the central nervous system and, unlike nociceptive pain conditions, is thought to be refractory to peripherally directed therapies. Nociplastic pain is also associated with hypersensitivity to painful and other sensory stimuli (such as visual stimuli). Nonpainful sensory measures have not been well
Noah Waller, Steven E. Harte, Richard E. Harris, Andrew Schrepf, Tristin Smith, Eric Ichesco, Chelsea Kaplan, Flavia Sunzini, Deeba Minhas, Wendy Marder, Sara R. Till, David A. Williams, Chad M. Brummett, Neil Basu, Sawsan As‐Sanie, Daniel J. Clauw   +15 more
wiley   +1 more source

Identification of clinical phenotypes in knee osteoarthritis: a systematic review of the literature [PDF]

, 2016
Background: Knee Osteoarthritis (KOA) is a heterogeneous pathology characterized by a complex and multifactorial nature. It has been hypothesised that these differences are due to the existence of underlying phenotypes representing different mechanisms ...
Allan, R., Dell'Isola, A., Marreiros, S.S.P., Smith, S.L., Steultjens, Martijn   +4 more
core   +3 more sources

Diet-derived circulating antioxidants and risk of knee osteoarthritis, hip osteoarthritis and rheumatoid arthritis: a two-sample Mendelian randomization study. [PDF]

Front Med (Lausanne), 2023
Huang L, Xie Y, Jin T, Wang M, Zeng Z, Zhang L, He W, Mai Y, Lu J, Cen H.   +9 more
europepmc   +1 more source

Tissue‐Specific and Spatially Dependent Metabolic Signatures Perturbed by Injury in Male and Female Mice

Arthritis &Rheumatology, EarlyView.
Objective Osteoarthritis, the leading cause of disability worldwide, disproportionately affects women, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven, Avery H. Welfley, Priyanka P. Brahmachary, Mark Greenwood, Donald F. Smith, Brian Bothner, Ronald K. June   +6 more
wiley   +1 more source

The distance between the femoral nerve and anterior acetabulum is significantly shorter in hip osteoarthritis than in non-osteoarthritis hip. [PDF]

BMC Musculoskelet Disord, 2021
Yoshino K, Hagiwara S, Nakamura J, Horikoshi T, Yokota H, Shimokawa K, Matsumoto K, Shiko Y, Kawasaki Y, Ohtori S.   +9 more
europepmc   +1 more source

Functional Impact of Structural Damage in Psoriatic Arthritis: Insights from a Prospective Cohort Study

Arthritis &Rheumatology, EarlyView.
Objective To examine the association between radiographic structural damage and physical function (PF) in psoriatic arthritis (PsA). Methods Data were analyzed from a large longitudinal PsA cohort. PF was measured using the Health Assessment Questionnaire (HAQ, 0–3) and Short Form‐36 PF subscale (SF‐36, 0–100); radiographic joint damage was measured ...
Pankti Mehta, Shangyi Gao, Virginia Carrizo Abarza, Fadi Kharouf, Daniel Pereira, Richard J. Cook, Dafna D. Gladman, Vinod Chandran, Denis Poddubnyy   +8 more
wiley   +1 more source