Results 71 to 80 of about 131,552 (309)

A Biomimetic Lubricant Captures Hyaluronic Acid In Situ to Regenerate Cartilage: From Bench to Bedside

Advanced Science, EarlyView.
(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin, Zijian Yan, Jiayi Chen, Xiaochao Wang, Ruibin Lin, Yunqi Fu, Zhaoying Lv, Bohui Wu, Xuewei Cao, Renjian Xie, Ming Dong, Chenxiao Zheng, Li Ren   +12 more
wiley   +1 more source

Do β-adrenoreceptor blocking drugs associate with reduced risk of symptomatic osteoarthritis and total joint replacement in the general population? A primary care-based, prospective cohort study using the Clinical Practice Research Datalink

BMJ Open, 2019
Introduction To investigate if β-adrenoreceptor blocking drug (β-blocker) prescription reduces the risk of knee or hip osteoarthritis, total joint replacement and analgesic prescription.Setting Primary care.Methods and analysis This is a cohort study ...
Mamas A Mamas, Christian Mallen, Abhishek Abhishek, Michael Doherty, Nick Townsend, Weiya Zhang, Georgina Nakafero, Matthew Grainge, Ana Valdes   +8 more
doaj   +1 more source

Laser‐Induced Periodic Phase‐Transition of 2D‐MoTe2 Nanograting Template for Frequency‐Shift Digital‐SERS Immunoassay of Autoimmune Disease

Advanced Science, EarlyView.
A protocol of fs‐laser‐induced periodic phase‐transition of 2D‐MoTe2 template, inducing AuNPs@1T’‐MoTe2 nanograting, is developed. The labeled AuNPs@1T’‐MoTe2 substrate conjugated with specialized immunoglobulin G demonstrates an unexpectedly high discrimination accuracy close to unity for serological diagnosis of rheumatoid arthritis by frequency ...
Yao Yao, Lulu Cao, Xiaolin Sun, Qiang Wang, Zhiyang Xu, Tianrui Zhai, Yan Zhao, Yijian Jiang, Zhanguo Li, Yinzhou Yan   +9 more
wiley   +1 more source

Does bariatric surgery prior to total hip or knee arthroplasty reduce post-operative complications and improve clinical outcomes for obese patients? Systematic review and meta-analysis. [PDF]

, 2016
AIMS: Our aim was to determine whether, based on the current literature, bariatric surgery prior to total hip (THA) or total knee arthroplasty (TKA) reduces the complication rates and improves the outcome following arthroplasty in obese patients. METHODS:
Aboelmagd, T, Hing, CB, MacGregor, A, Smith, TO   +3 more
core   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Physical Activity Minimum Threshold Predicting Improved Function in Adults With Lower‐Extremity Symptoms [PDF]

, 2017
Objective To identify an evidence‐based minimum physical activity threshold to predict improved or sustained high function for adults with lower‐extremity joint symptoms.
Ainsworth, Barbara, Chang, Rowland W., Dunlop, Dorothy D., Ehrlich-Jones, Linda S., Gilbert, Abigail L., Lee, Jungwha, Pellegrini, Christine A., Pinto, Daniel, Semanik, Pamela A., Song, Jing   +9 more
core   +1 more source

Chondrocalcinosis is common in the absence of knee involvement [PDF]

, 2012
Introduction: We aimed to describe the distribution of radiographic chondrocalcinosis (CC) and to examine whether metacarpophalangeal joint (MCPJ) calcification and CC at other joints occurs in the absence of knee involvement.
Abhishek, Abhishek, Doherty, Michael, Doherty, Sally A., Maciewicz, Rose A., Muir, Kenneth, Zhang, Weiya   +5 more
core   +3 more sources

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

An update on joint-specific outcome measures in total hip replacement

Rheumatology, 2020
This is the latest review of joint-specific tools used to evaluate patients undergoing total hip replacement (THR) surgery, which is an effective treatment for end-stage osteoarthritis.
Łukasz Pulik, Krzysztof Romaniuk, Kaja Jaśkiewicz, Paweł Wojtyński, Paweł Łęgosz, Paweł Małdyk   +5 more
doaj   +1 more source

Association between circulating 25-hydroxyvitamin D concentrations and hip replacement for osteoarthritis: a prospective cohort study

BMC Musculoskeletal Disorders, 2021
Background To examine the association between circulating 25(OH)D concentrations and incidence of total hip replacement for osteoarthritis in a prospective cohort study.
Sultana Monira Hussain, Yuanyuan Wang, Alicia K. Heath, Graham G. Giles, Dallas R. English, Darryl W. Eyles, Elizabeth J. Williamson, Stephen E. Graves, Anita E. Wluka, Flavia M. Cicuttini   +9 more
doaj   +1 more source