Results 61 to 70 of about 131,552 (309)

Exploring the causal link among statin drugs and the osteoarthritis risk based on Mendelian randomization research

Frontiers in Genetics
PurposeStatins may have a protective effect against osteoarthritis (including knee osteoarthritis and hip osteoarthritis); however, the link between statins and osteoarthritis risk is incompletely established.
Wenjie Chen, Zhi Sun, Xinhai Xiong, Haitao Tan, Junhao Hu, Chenrui Liu, Cheng Chen   +6 more
doaj   +1 more source

Outcomes of Femoral Neck Fracture Surgery Compared Elective Total Hip Arthroplasty: Evaluation of 340 Patients

Bagcilar Medical Bulletin, 2022
Objective:This study aims to determine the frequency of total hip arthroplasty and hemiarthroplasty in patients with femoral neck fractures (FNF); and to identify whether there is a difference between patients who underwent hip arthroplasty with the ...
İbrahim Eke
doaj   +1 more source

Mild acetabular dysplasia and risk of osteoarthritis of the hip : a case-control study [PDF]

, 2010
Objective To determine whether mild variation in acetabular depth (AD) and shape is a risk factor for osteoarthritis (OA) of the hip. Methods The unaffected contralateral hip of patients with unilateral hip OA was compared with hips of asymptomatic ...
Doherty, Michael, Doherty, Sally A., Jenkins, Wendy D., Maciewicz, Rose A., McWilliams, Daniel F., Muir, Kenneth, Zhang, Weiya   +6 more
core   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Factors associated with upper leg muscle strength in knee osteoarthritis: A scoping review

Journal of Rehabilitation Medicine, 2017
Objective: Muscle weakness is common and strongly related to clinical outcome in patients with knee or hip osteoarthritis. To date, there is no clear overview of the information on factors associated with muscle strength in knee and hip osteoarthritis ...
Arjan H de Zwart, Joost Dekker, Willem Lems, Leo D. Roorda, Martin van der Esch, Marike van der Leeden   +5 more
doaj   +1 more source

Mechanical Overloading‐Induced Nanomineral Crystal Perturbation from the Osteochondral Interface: A Potential Initiator of Osteoarthritis

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Nan Jiang, Rong Ren, Zhan Su, Jiahao Zhou, Pinyin Cao, Sicheng Zhang, Zhen Li, Chao Li, Songsong Zhu   +8 more
wiley   +1 more source

Surgical management of hip osteoarthritis [PDF]

Canadian Medical Association Journal, 2013
Osteoarthritis is a leading cause of pain, disability and health care use among adults. The hip is the second most common large joint affected by osteoarthritis.[1][1]–[3][2] Although research has advanced our knowledge of osteoarthritis, no therapies currently exist that halt progression of ...
Rajiv, Gandhi, Anthony V, Perruccio, Nizar N, Mahomed   +2 more
openaire   +2 more sources

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

The two-year incidence of hip osteoarthritis after arthroscopic hip surgery for femoroacetabular impingement syndrome

BMC Musculoskeletal Disorders, 2019
Background One of the reported goals of hip preservation surgery is to prevent or delay the onset of osteoarthritis. This includes arthroscopic surgery to manage Femoroacetabular Impingement (FAI) Syndrome.
Daniel I. Rhon, Tina A. Greenlee, Charles Dennis Sissel, Michael P. Reiman   +3 more
doaj   +1 more source

Patient Outcomes Following Hip and Knee Joint Replacement Surgery: Role of the Social and Physical Environment in Recovery [PDF]

, 2016
Osteoarthritis is a degenerative joint disease that affects over 27 million Americans (Centers for Disease Control & Prevention, 2014). Joint replacement surgery is often recommended for patients who do not respond to conventional medical treatment. Post-
Sampson, Brittany Anne
core   +1 more source